ZA899689B - Method of manufacturing lactulose - Google Patents
Method of manufacturing lactuloseInfo
- Publication number
- ZA899689B ZA899689B ZA899689A ZA899689A ZA899689B ZA 899689 B ZA899689 B ZA 899689B ZA 899689 A ZA899689 A ZA 899689A ZA 899689 A ZA899689 A ZA 899689A ZA 899689 B ZA899689 B ZA 899689B
- Authority
- ZA
- South Africa
- Prior art keywords
- solution
- ion exchanger
- sodium ions
- lactulose
- boric acid
- Prior art date
Links
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 title abstract 3
- 229960000511 lactulose Drugs 0.000 title abstract 3
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000000243 solution Substances 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 3
- 239000004327 boric acid Substances 0.000 abstract 3
- 239000012084 conversion product Substances 0.000 abstract 3
- 150000002500 ions Chemical class 0.000 abstract 3
- 229910001415 sodium ion Inorganic materials 0.000 abstract 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 229910021538 borax Inorganic materials 0.000 abstract 2
- 239000008101 lactose Substances 0.000 abstract 2
- 239000004328 sodium tetraborate Substances 0.000 abstract 2
- 235000010339 sodium tetraborate Nutrition 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000909 electrodialysis Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3843022 | 1988-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA899689B true ZA899689B (en) | 1990-09-26 |
Family
ID=6369721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA899689A ZA899689B (en) | 1988-12-21 | 1989-12-18 | Method of manufacturing lactulose |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5071530A (xx) |
| EP (1) | EP0375046B1 (xx) |
| JP (1) | JPH07119231B2 (xx) |
| CN (1) | CN1036406C (xx) |
| AT (1) | ATE104306T1 (xx) |
| AU (1) | AU615600B2 (xx) |
| CA (1) | CA2005859C (xx) |
| DE (1) | DE68914621T2 (xx) |
| DK (1) | DK641089A (xx) |
| ES (1) | ES2050789T3 (xx) |
| IE (1) | IE62815B1 (xx) |
| IL (1) | IL92755A (xx) |
| NZ (1) | NZ231830A (xx) |
| ZA (1) | ZA899689B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK170977B1 (da) * | 1988-04-28 | 1996-04-09 | Duphar Int Res | Fremgangsmåde til fremstilling af lactulose |
| CA2153362A1 (en) * | 1994-07-11 | 1996-01-12 | Hendrik Pluim | Process for the separation of lactulose |
| EP0692542A1 (en) * | 1994-07-11 | 1996-01-17 | Duphar International Research B.V | Process for the separation of lactulose |
| KR20080053708A (ko) | 2006-12-11 | 2008-06-16 | 씨제이제일제당 (주) | 높은 전환율의 갈락토스 이성화 반응을 이용한 타가토스의제조방법 |
| CN101182563B (zh) * | 2007-11-02 | 2011-06-22 | 江南大学 | 一种用共固定化乳糖酶和葡萄糖异构酶制备乳果糖的方法 |
| CN101182508B (zh) * | 2007-11-02 | 2010-11-10 | 江南大学 | 一种乳糖酶和葡萄糖异构酶的共固定化方法 |
| KR100964091B1 (ko) | 2008-01-28 | 2010-06-16 | 씨제이제일제당 (주) | 대두 올리고당을 이용한 타가토스의 제조 방법 |
| CN102503992A (zh) * | 2011-09-20 | 2012-06-20 | 江苏汉斯通药业有限公司 | 乳果糖浓溶液的制备方法 |
| CN104766821A (zh) * | 2014-01-02 | 2015-07-08 | 大族激光科技产业集团股份有限公司 | 一种裂片装置及裂片方法 |
| CN104059110A (zh) * | 2014-06-11 | 2014-09-24 | 江苏汉斯通药业有限公司 | 乳果糖浓溶液的生产工艺 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3546206A (en) * | 1967-09-20 | 1970-12-08 | Kraftco Corp | Method of making lactulose |
| US3505309A (en) * | 1967-09-25 | 1970-04-07 | Research Corp | Process for lactulose |
| AT315775B (de) * | 1970-10-16 | 1974-06-10 | Ennser Zuckerfabriks Ag | Verfahren zur Entfernung von Nichtzuckerstoffen aus technischen Zuckerlösungen |
| US3850905A (en) * | 1972-10-30 | 1974-11-26 | Kraftco Corp | Conversion of aldose sugars to ketose sugars |
| US4004587A (en) * | 1975-06-13 | 1977-01-25 | Baxter Travenol Laboratories, Inc. | Parenteral liquid administration set with non-air blocking filter |
| US4226977A (en) * | 1976-05-27 | 1980-10-07 | Uop Inc. | Process for separating a ketose from an aldose by selective adsorption |
| IT1099668B (it) * | 1978-09-29 | 1985-09-28 | Molteni L & C Dei Filli Alitti | Processo per la produzione di lattulosio |
| US4273922A (en) * | 1980-03-21 | 1981-06-16 | The United States Of America As Represented By The Secretary Of Agriculture | Ketose sugars from aldose sugars |
| US4394178A (en) * | 1981-12-10 | 1983-07-19 | Union Carbide Corporation | Bulk lactulose/lactose separation by selective adsorption on zeolitic molecular sieves |
| US4536221A (en) * | 1982-12-17 | 1985-08-20 | Sirac Spa | Process for preparing lactulose from lactose, in the form of a syrup or a crystalline product |
| HU190624B (en) * | 1983-03-23 | 1986-09-29 | Biogal Gyogyszergyar,Hu | Process for production of 4-o-b-d-galactopiranosile-d-fructofuranose suitable for medical purpuses |
| IT1163540B (it) * | 1983-06-20 | 1987-04-08 | Sirac Srl | Procedimento per la purificazione dello sciroppo di lattulosio |
| IT1206140B (it) * | 1984-03-22 | 1989-04-14 | Sirac Srl | Procedimento per la purificazione di lattulosio. |
| CA1321583C (en) * | 1988-09-01 | 1993-08-24 | Eiki Deya | Production process of high-purity lactulose syrup |
-
1989
- 1989-12-14 DE DE68914621T patent/DE68914621T2/de not_active Expired - Lifetime
- 1989-12-14 AT AT89203208T patent/ATE104306T1/de not_active IP Right Cessation
- 1989-12-14 ES ES89203208T patent/ES2050789T3/es not_active Expired - Lifetime
- 1989-12-14 EP EP89203208A patent/EP0375046B1/en not_active Expired - Lifetime
- 1989-12-18 DK DK641089A patent/DK641089A/da not_active Application Discontinuation
- 1989-12-18 ZA ZA899689A patent/ZA899689B/xx unknown
- 1989-12-18 CA CA002005859A patent/CA2005859C/en not_active Expired - Fee Related
- 1989-12-18 NZ NZ231830A patent/NZ231830A/xx unknown
- 1989-12-18 US US07/451,782 patent/US5071530A/en not_active Expired - Fee Related
- 1989-12-18 IL IL9275589A patent/IL92755A/en unknown
- 1989-12-19 IE IE408589A patent/IE62815B1/en not_active IP Right Cessation
- 1989-12-20 JP JP1328595A patent/JPH07119231B2/ja not_active Expired - Lifetime
- 1989-12-21 AU AU47166/89A patent/AU615600B2/en not_active Ceased
-
1990
- 1990-06-20 CN CN90103099A patent/CN1036406C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IL92755A0 (en) | 1990-09-17 |
| CA2005859C (en) | 1999-11-23 |
| IL92755A (en) | 1994-11-11 |
| EP0375046B1 (en) | 1994-04-13 |
| IE894085L (en) | 1990-06-21 |
| ES2050789T3 (es) | 1994-06-01 |
| NZ231830A (en) | 1991-02-26 |
| ATE104306T1 (de) | 1994-04-15 |
| IE62815B1 (en) | 1995-03-08 |
| CA2005859A1 (en) | 1990-06-21 |
| JPH07119231B2 (ja) | 1995-12-20 |
| CN1057485A (zh) | 1992-01-01 |
| AU4716689A (en) | 1990-06-28 |
| DE68914621T2 (de) | 1994-07-21 |
| CN1036406C (zh) | 1997-11-12 |
| US5071530A (en) | 1991-12-10 |
| DE68914621D1 (de) | 1994-05-19 |
| AU615600B2 (en) | 1991-10-03 |
| DK641089A (da) | 1990-06-22 |
| DK641089D0 (da) | 1989-12-18 |
| EP0375046A1 (en) | 1990-06-27 |
| JPH02300195A (ja) | 1990-12-12 |
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