ZA899451B - Catanospermine esters in the inhibition of tumor metastasis - Google Patents

Catanospermine esters in the inhibition of tumor metastasis

Info

Publication number
ZA899451B
ZA899451B ZA899451A ZA899451A ZA899451B ZA 899451 B ZA899451 B ZA 899451B ZA 899451 A ZA899451 A ZA 899451A ZA 899451 A ZA899451 A ZA 899451A ZA 899451 B ZA899451 B ZA 899451B
Authority
ZA
South Africa
Prior art keywords
inhibition
esters
catanospermine
tumor metastasis
administration
Prior art date
Application number
ZA899451A
Other languages
English (en)
Inventor
Sai Prasad Sunkara
Prasad Sunkara Sai
Paul Saiho Liu
Saiho Liu Paul
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA899451B publication Critical patent/ZA899451B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA899451A 1988-12-15 1989-12-11 Catanospermine esters in the inhibition of tumor metastasis ZA899451B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/284,510 US4952585A (en) 1988-12-15 1988-12-15 Castanospermine esters in the inhibition of tumor metastasis

Publications (1)

Publication Number Publication Date
ZA899451B true ZA899451B (en) 1990-09-26

Family

ID=23090466

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA899451A ZA899451B (en) 1988-12-15 1989-12-11 Catanospermine esters in the inhibition of tumor metastasis

Country Status (12)

Country Link
US (1) US4952585A (fr)
EP (1) EP0373663B1 (fr)
JP (1) JP2963476B2 (fr)
KR (1) KR0135278B1 (fr)
AT (1) ATE96320T1 (fr)
AU (1) AU621431B2 (fr)
DE (1) DE68910287T2 (fr)
DK (1) DK634689A (fr)
ES (1) ES2061912T3 (fr)
IE (1) IE62014B1 (fr)
PH (1) PH26024A (fr)
ZA (1) ZA899451B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US4970317A (en) * 1989-08-08 1990-11-13 Merrell Dow Pharmaceuticals Inc. Process for the preparation of castanospermine esters
ES2212292T3 (es) * 1997-05-22 2004-07-16 Aventis Pharmaceuticals Inc. Procedimiento para preparar 6-0-monoesteres de castanospermina.
US5959111A (en) * 1997-05-22 1999-09-28 Hoechst Marion Roussel, Inc. Process for preparing 6-0-monoesters of castanospermine
US6013459A (en) * 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
KR20090040906A (ko) * 2006-08-02 2009-04-27 유나이티드 세러퓨틱스 코오포레이션 바이러스 감염의 리포솜 치료
KR20100127842A (ko) * 2008-03-26 2010-12-06 유니버시티 오브 옥스퍼드 소포체 표적화 리포좀
US8226684B2 (en) * 2008-12-22 2012-07-24 Ethicon, Inc. Surgical sutures having collapsible tissue anchoring protrusions and methods therefor
CN102427804A (zh) * 2009-03-27 2012-04-25 牛津大学之校长及学者 降低胆固醇水平的脂质体
US20190046497A1 (en) * 2016-02-14 2019-02-14 Yeda Research And Development Co., Ltd. Methods of modulating protein exocytosis and uses of same in therapy
WO2018059214A1 (fr) 2016-09-29 2018-04-05 广州君赫生物科技有限公司 Composés affectant la synthèse de saicar, et applications
EP3613731A4 (fr) 2017-04-20 2021-01-13 Geneheal Biotechnology Co., Ltd. Applications de la spermidine et de son dérivé
AU2018253671B2 (en) 2017-04-20 2020-08-20 Geneheal Biotechnology Co., Ltd. Applications of spermine and its derivative in preparation of antitumor drug

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792558A (en) * 1987-05-29 1988-12-20 Merrell Dow Pharmaceuticals Inc. Castanospermine for inhibiting tumor metastasis
CA1315276C (fr) * 1987-07-02 1993-03-30 Paul S. Liu Esters et glucosides de castanospermine
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
AU618838B2 (en) * 1988-08-10 1992-01-09 Praxis Pharmaceuticals, Inc. Use of castanospermine as an anti-inflammatory and immunosuppressant agent

Also Published As

Publication number Publication date
DK634689A (da) 1990-06-16
AU4670789A (en) 1990-06-21
IE62014B1 (en) 1994-12-14
ES2061912T3 (es) 1994-12-16
DK634689D0 (da) 1989-12-14
KR910011256A (ko) 1991-08-07
AU621431B2 (en) 1992-03-12
EP0373663B1 (fr) 1993-10-27
US4952585A (en) 1990-08-28
DE68910287T2 (de) 1994-03-10
DE68910287D1 (de) 1993-12-02
JP2963476B2 (ja) 1999-10-18
PH26024A (en) 1992-01-24
KR0135278B1 (ko) 1998-04-23
EP0373663A2 (fr) 1990-06-20
ATE96320T1 (de) 1993-11-15
EP0373663A3 (en) 1990-09-12
JPH02212427A (ja) 1990-08-23
IE894009L (en) 1990-06-15

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