ZA898783B - Renin-inhibiting dipeptides,a process for the preparation thereof,agents containing these,and the use thereof - Google Patents

Renin-inhibiting dipeptides,a process for the preparation thereof,agents containing these,and the use thereof

Info

Publication number
ZA898783B
ZA898783B ZA898783A ZA898783A ZA898783B ZA 898783 B ZA898783 B ZA 898783B ZA 898783 A ZA898783 A ZA 898783A ZA 898783 A ZA898783 A ZA 898783A ZA 898783 B ZA898783 B ZA 898783B
Authority
ZA
South Africa
Prior art keywords
renin
preparation
agents containing
dipeptides
inhibiting
Prior art date
Application number
ZA898783A
Other languages
English (en)
Inventor
Wolfgang Rueger
Rueger Wolfgang
Hansjoerg Urbach
Urbach Hansjoerg
Dieter Ruppert
Ruppert Dieter
Bernward Schoelkens
Schoelkens Bernward
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA898783B publication Critical patent/ZA898783B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
ZA898783A 1988-11-19 1989-11-17 Renin-inhibiting dipeptides,a process for the preparation thereof,agents containing these,and the use thereof ZA898783B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839128A DE3839128A1 (de) 1988-11-19 1988-11-19 Renin-hemmende dipeptide, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung

Publications (1)

Publication Number Publication Date
ZA898783B true ZA898783B (en) 1990-08-29

Family

ID=6367478

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA898783A ZA898783B (en) 1988-11-19 1989-11-17 Renin-inhibiting dipeptides,a process for the preparation thereof,agents containing these,and the use thereof

Country Status (12)

Country Link
EP (1) EP0370383A3 (xx)
JP (1) JPH02180897A (xx)
KR (1) KR900007869A (xx)
AU (1) AU616072B2 (xx)
DE (1) DE3839128A1 (xx)
DK (1) DK578689A (xx)
FI (1) FI895460A0 (xx)
HU (1) HU201962B (xx)
IL (1) IL92347A0 (xx)
NO (1) NO894593L (xx)
PT (1) PT92329A (xx)
ZA (1) ZA898783B (xx)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
NZ222755A (en) * 1986-12-23 1989-11-28 Warner Lambert Co Renin inhibiting acyl peptide derivatives containing two to four amino acid residues, and pharmaceutical compositions
DE3815913A1 (de) * 1988-05-10 1989-11-23 Sandoz Ag Neue reninhemmer, verfahren zu deren herstellung und deren verwendung
DE3839559A1 (de) * 1988-11-24 1990-05-31 Hoechst Ag Renin-hemmende aminodiol-derivate

Also Published As

Publication number Publication date
NO894593L (no) 1990-05-21
AU616072B2 (en) 1991-10-17
HU201962B (en) 1991-01-28
JPH02180897A (ja) 1990-07-13
DK578689A (da) 1990-05-20
FI895460A0 (fi) 1989-11-16
NO894593D0 (no) 1989-11-17
DE3839128A1 (de) 1990-05-31
HUT51650A (en) 1990-05-28
IL92347A0 (en) 1990-07-26
PT92329A (pt) 1990-05-31
AU4479989A (en) 1990-09-13
HU895949D0 (en) 1990-02-28
EP0370383A3 (de) 1991-07-17
KR900007869A (ko) 1990-06-02
EP0370383A2 (de) 1990-05-30
DK578689D0 (da) 1989-11-17

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