AU4479989A - Renin-inhibiting dipeptides, a process for the preparation thereof, agents containing these, and the use thereof - Google Patents

Renin-inhibiting dipeptides, a process for the preparation thereof, agents containing these, and the use thereof

Info

Publication number
AU4479989A
AU4479989A AU44799/89A AU4479989A AU4479989A AU 4479989 A AU4479989 A AU 4479989A AU 44799/89 A AU44799/89 A AU 44799/89A AU 4479989 A AU4479989 A AU 4479989A AU 4479989 A AU4479989 A AU 4479989A
Authority
AU
Australia
Prior art keywords
renin
preparation
agents containing
dipeptides
inhibiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU44799/89A
Other versions
AU616072B2 (en
Inventor
Wolfgang Ruger
Dieter Ruppert
Bernward Scholkens
Hansjorg Urbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4479989A publication Critical patent/AU4479989A/en
Application granted granted Critical
Publication of AU616072B2 publication Critical patent/AU616072B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
AU44799/89A 1988-11-19 1989-11-17 Renin-inhibiting dipeptides, a process for the preparation thereof, agents containing these, and the use thereof Expired - Fee Related AU616072B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3839128A DE3839128A1 (en) 1988-11-19 1988-11-19 RENIN-INHIBITING DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
DE3839128 1988-11-19

Publications (2)

Publication Number Publication Date
AU4479989A true AU4479989A (en) 1990-09-13
AU616072B2 AU616072B2 (en) 1991-10-17

Family

ID=6367478

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44799/89A Expired - Fee Related AU616072B2 (en) 1988-11-19 1989-11-17 Renin-inhibiting dipeptides, a process for the preparation thereof, agents containing these, and the use thereof

Country Status (12)

Country Link
EP (1) EP0370383A3 (en)
JP (1) JPH02180897A (en)
KR (1) KR900007869A (en)
AU (1) AU616072B2 (en)
DE (1) DE3839128A1 (en)
DK (1) DK578689A (en)
FI (1) FI895460A0 (en)
HU (1) HU201962B (en)
IL (1) IL92347A0 (en)
NO (1) NO894593L (en)
PT (1) PT92329A (en)
ZA (1) ZA898783B (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
NZ222755A (en) * 1986-12-23 1989-11-28 Warner Lambert Co Renin inhibiting acyl peptide derivatives containing two to four amino acid residues, and pharmaceutical compositions
DE3815913A1 (en) * 1988-05-10 1989-11-23 Sandoz Ag NEW RENINHERMERS, PROCESS FOR THEIR PRODUCTION AND THEIR USE
DE3839559A1 (en) * 1988-11-24 1990-05-31 Hoechst Ag RENIN-INHIBITING AMINODIOL DERIVATIVES

Also Published As

Publication number Publication date
AU616072B2 (en) 1991-10-17
NO894593L (en) 1990-05-21
EP0370383A3 (en) 1991-07-17
DK578689A (en) 1990-05-20
DE3839128A1 (en) 1990-05-31
HUT51650A (en) 1990-05-28
NO894593D0 (en) 1989-11-17
HU201962B (en) 1991-01-28
JPH02180897A (en) 1990-07-13
HU895949D0 (en) 1990-02-28
FI895460A0 (en) 1989-11-16
IL92347A0 (en) 1990-07-26
KR900007869A (en) 1990-06-02
EP0370383A2 (en) 1990-05-30
PT92329A (en) 1990-05-31
ZA898783B (en) 1990-08-29
DK578689D0 (en) 1989-11-17

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