ZA898775B - Cyclopropyl-substituted azolylmethylcarbinols,processes for their preparation and their use as medicaments - Google Patents

Cyclopropyl-substituted azolylmethylcarbinols,processes for their preparation and their use as medicaments

Info

Publication number
ZA898775B
ZA898775B ZA898775A ZA898775A ZA898775B ZA 898775 B ZA898775 B ZA 898775B ZA 898775 A ZA898775 A ZA 898775A ZA 898775 A ZA898775 A ZA 898775A ZA 898775 B ZA898775 B ZA 898775B
Authority
ZA
South Africa
Prior art keywords
medicaments
cyclopropyl
preparation
processes
azolylmethylcarbinols
Prior art date
Application number
ZA898775A
Other languages
English (en)
Inventor
Burkhard Fugmann
Fugmann Burkhard
Manfred Plempel
Plempel Manfred
Klaus Stroech
Stroech Klaus
Karl Heinz Buechel
Heinz Buechel Karl
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA898775B publication Critical patent/ZA898775B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/45—Carboxylic acid nitriles having cyano groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA898775A 1988-11-19 1989-11-17 Cyclopropyl-substituted azolylmethylcarbinols,processes for their preparation and their use as medicaments ZA898775B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839170A DE3839170A1 (de) 1988-11-19 1988-11-19 Cyclopropyl-substituierte azolylmethylcarbinole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA898775B true ZA898775B (en) 1990-08-29

Family

ID=6367500

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA898775A ZA898775B (en) 1988-11-19 1989-11-17 Cyclopropyl-substituted azolylmethylcarbinols,processes for their preparation and their use as medicaments

Country Status (9)

Country Link
US (1) US5059615A (fr)
EP (1) EP0370300B1 (fr)
JP (1) JP2839161B2 (fr)
KR (1) KR0128662B1 (fr)
AT (1) ATE103907T1 (fr)
CA (1) CA2003213C (fr)
DE (2) DE3839170A1 (fr)
ES (1) ES2052863T3 (fr)
ZA (1) ZA898775B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4206529A1 (de) * 1992-03-02 1993-09-09 Bayer Ag Azolylmethyl-cyclopropyl-derivate
CN105164111B (zh) * 2012-12-19 2018-11-20 巴斯夫欧洲公司 取代[1,2,4]三唑及其作为杀真菌剂的用途
AR100743A1 (es) * 2014-06-06 2016-10-26 Basf Se Compuestos de [1,2,4]triazol sustituido
JP2017523967A (ja) * 2014-07-18 2017-08-24 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 植物の非生物的なストレスに対する活性剤としての置換されているビニルシアノシクロアルカノール類、アルキニルシアノシクロアルカノール類、ビニルシアノヘテロシクロアルカノール類及びアルキニルシアノヘテロシクロアルカノール類
AR101214A1 (es) 2014-07-22 2016-11-30 Bayer Cropscience Ag Ciano-cicloalquilpenta-2,4-dienos, ciano-cicloalquilpent-2-en-4-inas, ciano-heterociclilpenta-2,4-dienos y ciano-heterociclilpent-2-en-4-inas sustituidos como principios activos contra el estrés abiótico de plantas
HUE044642T2 (hu) 2015-01-22 2019-11-28 Sanofi Aventis Deutschland Eljárás 2-[4-(ciklopropánkarbonil)fenil]-2-metil-propánnitril elõállítására
KR20180100313A (ko) * 2015-11-17 2018-09-10 다우 아그로사이언시즈 엘엘씨 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-히드록시-3-(1h-1,2,4-트리아졸-1-일)프로필)피리딘-3-일)옥시)벤조니트릴 및 제조방법
JP6898340B2 (ja) * 2015-11-17 2021-07-07 コルテバ アグリサイエンス エルエルシー ４−（（６−（２−（２，４−ジフルオロフェニル）−１，１−ジフルオロ−２−ヒドロキシ−３−（１ｈ−１，２，４−トリアゾール−１−イル）プロピル）ピリジン−３−イル）オキシ）ベンゾニトリル及び調製方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0106515B1 (fr) * 1982-09-30 1988-12-28 Pfizer Limited Dérivés du triazole comme agents antifongiques
EP0180850A3 (fr) * 1984-11-02 1987-05-27 Bayer Ag Dérivés d'azolylméthyl-cyclopropyl-carbinols antimycotiques
US4859232A (en) * 1986-12-05 1989-08-22 Monsanto Company Substituted-aryl cyclopropanecarbonitriles and derivatives thereof as herbicide antidotes
DE3732385A1 (de) * 1987-09-25 1989-04-06 Bayer Ag Hydroxyalkylcyclopropyl1-1,2,4-triazolyl- oder -imidazolyl-derivate und ihre verwendung als antimykotische mittel
JP2681648B2 (ja) * 1988-03-29 1997-11-26 富山化学工業株式会社 新規な２−アゾリル−１−シクロプロピルエタノール誘導体およびその塩

Also Published As

Publication number Publication date
JPH02243673A (ja) 1990-09-27
DE58907399D1 (de) 1994-05-11
CA2003213A1 (fr) 1990-05-19
JP2839161B2 (ja) 1998-12-16
US5059615A (en) 1991-10-22
ATE103907T1 (de) 1994-04-15
ES2052863T3 (es) 1994-07-16
KR900007816A (ko) 1990-06-02
EP0370300A3 (fr) 1991-07-03
DE3839170A1 (de) 1990-05-31
EP0370300A2 (fr) 1990-05-30
CA2003213C (fr) 1999-08-03
EP0370300B1 (fr) 1994-04-06
KR0128662B1 (ko) 1998-04-04

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