ZA897551B - Substituted aromatic compounds having an action on the central nervous system - Google Patents
Substituted aromatic compounds having an action on the central nervous systemInfo
- Publication number
- ZA897551B ZA897551B ZA897551A ZA897551A ZA897551B ZA 897551 B ZA897551 B ZA 897551B ZA 897551 A ZA897551 A ZA 897551A ZA 897551 A ZA897551 A ZA 897551A ZA 897551 B ZA897551 B ZA 897551B
- Authority
- ZA
- South Africa
- Prior art keywords
- action
- nervous system
- central nervous
- aromatic compounds
- substituted aromatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Eye Examination Apparatus (AREA)
- Radio Relay Systems (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8802470 | 1988-10-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA897551B true ZA897551B (en) | 1990-07-25 |
Family
ID=19853017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA897551A ZA897551B (en) | 1988-10-10 | 1989-10-04 | Substituted aromatic compounds having an action on the central nervous system |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5051424A (enExample) |
| EP (1) | EP0365064B1 (enExample) |
| JP (1) | JPH02134374A (enExample) |
| KR (1) | KR900006308A (enExample) |
| AT (1) | ATE81651T1 (enExample) |
| AU (1) | AU621408B2 (enExample) |
| CA (1) | CA2000060A1 (enExample) |
| DE (1) | DE68903263T2 (enExample) |
| DK (1) | DK498889A (enExample) |
| ES (1) | ES2052890T3 (enExample) |
| FI (1) | FI894783A7 (enExample) |
| GR (1) | GR3006821T3 (enExample) |
| IE (1) | IE893129L (enExample) |
| NZ (1) | NZ230934A (enExample) |
| PT (1) | PT91932B (enExample) |
| ZA (1) | ZA897551B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0598123A4 (en) * | 1991-07-19 | 1995-02-15 | Zeria Pharm Co Ltd | PIPERAZINE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THEM. |
| GB9119932D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| ES2162792T3 (es) * | 1991-09-18 | 2002-01-16 | Glaxo Group Ltd | Derivados de benzanilida como antagonistas de 5-ht1d. |
| GB9119920D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| JP2768008B2 (ja) * | 1991-10-04 | 1998-06-25 | 大正製薬株式会社 | アルコキシフェニルアルキルアミン誘導体 |
| US5486526A (en) * | 1992-04-01 | 1996-01-23 | The University Of Toledo | Histamine H3 -receptor antagonists and therapeutic uses thereof |
| EP0566189A1 (en) * | 1992-04-13 | 1993-10-20 | Akzo N.V. | Psychotropic piperazine derivative |
| DE69426771T2 (de) * | 1993-06-25 | 2001-06-13 | Pola Chemical Industries, Inc. | Dopaminreinkorporationshemmer zur behandlung des parkinsonschen syndroms |
| WO2013086496A2 (en) * | 2011-12-09 | 2013-06-13 | Research Triangle Institute | 1-substituted 4-arylpiperazine as kappa opioid receptor antagonists |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE564238A (enExample) * | ||||
| DE1137733B (de) * | 1954-06-05 | 1962-10-11 | Chem Fab Promonta G M B H | Verfahren zur Herstellung von Aryl- und Thienylmethylphenylalkylaminen |
| US2927924A (en) * | 1958-04-03 | 1960-03-08 | Lilly Co Eli | Novel phenethyl-substituted piperazines |
| IL48319A0 (en) * | 1974-10-26 | 1975-12-31 | Merck Patent Gmbh | Araliphatic nitrogen compounds and a process for their preparation |
| US3997540A (en) * | 1975-07-21 | 1976-12-14 | Burroughs Wellcome Co. | O [(O-piperazinocarbonyl-phenyl)-thio]-benzoates |
| US4562201A (en) * | 1982-07-26 | 1985-12-31 | American Hospital Supply Corporation | Aminomethyl benzanilides |
| HU196194B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing new 1-4 disubstituted piperazines and pharmaceuticals comprising the compounds |
| HU196195B (en) * | 1986-04-28 | 1988-10-28 | Richter Gedeon Vegyeszet | Process for producing 1,4-disubstituted piperazine derivatives and pharmaceuticals comprising the compounds |
| GB8713061D0 (en) * | 1987-06-04 | 1987-07-08 | Beecham Group Plc | Compounds |
-
1989
- 1989-09-28 ES ES89202429T patent/ES2052890T3/es not_active Expired - Lifetime
- 1989-09-28 AT AT89202429T patent/ATE81651T1/de not_active IP Right Cessation
- 1989-09-28 DE DE8989202429T patent/DE68903263T2/de not_active Expired - Fee Related
- 1989-09-28 EP EP89202429A patent/EP0365064B1/en not_active Expired - Lifetime
- 1989-09-29 IE IE893129A patent/IE893129L/xx unknown
- 1989-10-02 CA CA002000060A patent/CA2000060A1/en not_active Abandoned
- 1989-10-04 ZA ZA897551A patent/ZA897551B/xx unknown
- 1989-10-06 NZ NZ230934A patent/NZ230934A/xx unknown
- 1989-10-09 FI FI894783A patent/FI894783A7/fi not_active Application Discontinuation
- 1989-10-09 AU AU42713/89A patent/AU621408B2/en not_active Ceased
- 1989-10-09 PT PT91932A patent/PT91932B/pt not_active IP Right Cessation
- 1989-10-09 DK DK498889A patent/DK498889A/da unknown
- 1989-10-09 JP JP1263799A patent/JPH02134374A/ja active Pending
- 1989-10-10 KR KR1019890014475A patent/KR900006308A/ko not_active Withdrawn
- 1989-10-16 US US07/422,311 patent/US5051424A/en not_active Expired - Fee Related
-
1993
- 1993-01-19 GR GR930400077T patent/GR3006821T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0365064A1 (en) | 1990-04-25 |
| DE68903263T2 (de) | 1993-05-19 |
| FI894783L (fi) | 1990-04-11 |
| PT91932A (pt) | 1990-04-30 |
| FI894783A0 (fi) | 1989-10-09 |
| AU4271389A (en) | 1990-04-12 |
| ES2052890T3 (es) | 1994-07-16 |
| US5051424A (en) | 1991-09-24 |
| EP0365064B1 (en) | 1992-10-21 |
| ATE81651T1 (de) | 1992-11-15 |
| FI894783A7 (fi) | 1990-04-11 |
| NZ230934A (en) | 1990-10-26 |
| DK498889A (da) | 1990-04-11 |
| KR900006308A (ko) | 1990-05-07 |
| GR3006821T3 (enExample) | 1993-06-30 |
| DK498889D0 (da) | 1989-10-09 |
| DE68903263D1 (de) | 1992-11-26 |
| IE893129L (en) | 1990-04-10 |
| JPH02134374A (ja) | 1990-05-23 |
| CA2000060A1 (en) | 1990-04-10 |
| PT91932B (pt) | 1995-05-31 |
| AU621408B2 (en) | 1992-03-12 |
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