ZA897533B - Use of basic nitro-phenyl-dihydorpyridine amides as medicaments,new compounds and processes for their preparation via new intermediates - Google Patents

Use of basic nitro-phenyl-dihydorpyridine amides as medicaments,new compounds and processes for their preparation via new intermediates

Info

Publication number
ZA897533B
ZA897533B ZA897533A ZA897533A ZA897533B ZA 897533 B ZA897533 B ZA 897533B ZA 897533 A ZA897533 A ZA 897533A ZA 897533 A ZA897533 A ZA 897533A ZA 897533 B ZA897533 B ZA 897533B
Authority
ZA
South Africa
Prior art keywords
dihydorpyridine
medicaments
amides
phenyl
processes
Prior art date
Application number
ZA897533A
Other languages
English (en)
Inventor
Juergen Stoltefuss
Stoltefuss Juergen
Eckhard Schwenner
Schwenner Eckhard
Rainer Gross
Gross Rainer
Siegbert Hebisch
Hebisch Siegbert
Matthias Schramm
Schramm Matthias
Martin Bechem
Bechem Martin
Claudia Hirth
Hirth Claudia
Johannes-Peter Stasch
Stasch Johannes-Peter
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA897533B publication Critical patent/ZA897533B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA897533A 1988-10-05 1989-10-04 Use of basic nitro-phenyl-dihydorpyridine amides as medicaments,new compounds and processes for their preparation via new intermediates ZA897533B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3833893A DE3833893A1 (de) 1988-10-05 1988-10-05 Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte

Publications (1)

Publication Number Publication Date
ZA897533B true ZA897533B (en) 1990-06-27

Family

ID=6364450

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897533A ZA897533B (en) 1988-10-05 1989-10-04 Use of basic nitro-phenyl-dihydorpyridine amides as medicaments,new compounds and processes for their preparation via new intermediates

Country Status (16)

Country Link
US (1) US5051433A (ja)
EP (1) EP0362635A1 (ja)
JP (1) JPH02169573A (ja)
KR (1) KR900006290A (ja)
CN (1) CN1041586A (ja)
AU (1) AU616057B2 (ja)
CA (1) CA2000080A1 (ja)
DE (1) DE3833893A1 (ja)
DK (1) DK489689A (ja)
FI (1) FI894678A (ja)
HU (1) HUT52054A (ja)
IL (1) IL91864A0 (ja)
NO (1) NO893757L (ja)
NZ (1) NZ230866A (ja)
PT (1) PT91883A (ja)
ZA (1) ZA897533B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3833892A1 (de) * 1988-10-05 1990-04-12 Bayer Ag Basische 4-aryl-dhp-amide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5571827A (en) * 1990-03-13 1996-11-05 Sepracor Inc. Methods and compositions for treating hypertension, angina and other disorders using optically pure s(-) nitrendipine
NL9001752A (nl) * 1990-08-02 1992-03-02 Cedona Pharm Bv Nieuwe 1,4-dihydropyridinederivaten.
AU5568300A (en) * 1999-06-23 2001-01-09 Ajinomoto Co., Inc. Novel dihydropyridine derivative
CN108928895A (zh) * 2018-08-13 2018-12-04 浙江迪萧环保科技有限公司 一种邻位双卤代羧酸的双极膜电渗析环化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
NO854021L (no) * 1984-10-26 1986-04-28 Bayer Ag 1,4-dihydropyridin-hydroksyaminer og fremgangsmaate til fremstilling derav.
EP0191724A3 (de) * 1985-01-15 1986-12-03 Sandoz Ag 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
DK8602336A (ja) * 1985-05-21 1986-11-22
JPS62174050A (ja) * 1985-10-21 1987-07-30 Nippon Shoji Kk ３−アミノカルボニル−１，４−ジヒドロピリジン−５−カルボン酸誘導体、その製法および医薬組成物
DE3601397A1 (de) * 1986-01-18 1987-07-23 Bayer Ag Substituierte 1,4-dihydropyridin-3-carbonsaeurepiperazide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JPS63208574A (ja) * 1987-02-24 1988-08-30 Sanwa Kagaku Kenkyusho Co Ltd １，４−ジヒドロピリジン誘導体及びその塩、これらの製法並びに該化合物を有効成分とする循環器系作用薬
DE3833892A1 (de) * 1988-10-05 1990-04-12 Bayer Ag Basische 4-aryl-dhp-amide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
AU4261189A (en) 1990-04-26
AU616057B2 (en) 1991-10-17
JPH02169573A (ja) 1990-06-29
CN1041586A (zh) 1990-04-25
HUT52054A (en) 1990-06-28
NO893757L (no) 1990-04-06
PT91883A (pt) 1990-04-30
KR900006290A (ko) 1990-05-07
US5051433A (en) 1991-09-24
CA2000080A1 (en) 1990-04-05
DK489689D0 (da) 1989-10-04
IL91864A0 (en) 1990-06-10
FI894678A0 (fi) 1989-10-03
NO893757D0 (no) 1989-09-21
NZ230866A (en) 1991-09-25
DE3833893A1 (de) 1990-04-12
HU895228D0 (en) 1990-01-28
EP0362635A1 (de) 1990-04-11
FI894678A (fi) 1990-04-06
DK489689A (da) 1990-04-06

Similar Documents

Publication Publication Date Title
HUT55014A (en) Process for producing substituted, with imidazol-ring-condensed six-member-heterocyclic compounds of angiotensine-ii-antagonistic activity and pharmaceutical compositions containing them
PH23341A (en) Morphinane derivatives,pharmaceutical composition containing said compounds and method of use thereof
GR860849B (en) 4-demethyl -4- epipodophyllotoxin derivatives process for their preparation and their use as medicaments
ZA868065B (en) Antihypertensive thieno-isoxazoles and-pyrazoles,a process and intermediates for their preparation and their use as medicaments
ZA901765B (en) Derivatives of thieno-triazolo-diazepine,a preparation process of the same and therapeutic compositions containing them
EP0264091A3 (en) 3-propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use
ZA862747B (en) Intermediates for the production of epipodophyilotoxin and related compounds and processes for the preparation and use thereof
ZA903305B (en) Thieno-triazolo-diazepine derivatives,a preparation process of the same and therapeutic compositions containing them
EP0315316A3 (en) Imidazole derivatives, process and intermediates for their preparation, pharmaceutical compositions containing them and their pharmaceutical use
EP0424848A3 (en) Aminopyridinylaminophenols and related compounds, a process and intermediates for their preparation and their use as medicaments
ZA865328B (en) Oxa-thia and d1-azabicycloalkane derivatives;process for their preparation and their use as pharmaceuticals
EP0216127A3 (en) 6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones, process for their preparation, their use as medicines, pharmaceutical compositions and intermediates
ZA897533B (en) Use of basic nitro-phenyl-dihydorpyridine amides as medicaments,new compounds and processes for their preparation via new intermediates
GR862249B (en) Dihydropyridin-2-hydroxyamine process for their preparation and their use as medicaments
AR242206A1 (es) Procedimiento para la preparacion de derivados de acido 3-desmetil-mevalonico, preparados farmaceuticos en base a los mismos,y productos intermediarios para uso exclusivo.
PT86470A (en) Novel carbamoyloxylabdanes intermediates and a process for the preparation thereof and their use as medicaments
ZA869126B (en) N-(pyrrol-1-yl)pyridinamines,a process for their preparation and their use as medicaments
ZA891413B (en) Derivatives of 1-arylsulfonyl-2-pyrrolidinone,process for their preparation and intermediates thus obtained,their use as medicaments and compositions containing them
DE3664635D1 (en) 7-hydroxyguanine compounds, process for preparing said compounds, pharmaceutical composition, and use thereof
EP0329563A3 (en) Benzocyclohexane and benzocycloheptane derivatives and their salts, process and intermediates for their preparation, their use as medicines and compositions containing them
ZA878659B (en) 12-halogenated forskolin derivatives,intermediates and a process for the preparation thereof and their use as medicaments
LTIP1719A (en) New bronchospasmolytic compounds, process for their preparation and pharmaceutical preparations containing them
GR861039B (en) Ethanobenzazepines process and intermediates for their preparation and their use as medicaments
PT80276B (en) Substituted 1-aminoalkylamino-4-aryloxypiperidines a process for their preparation intermediates thereof and their use as medicaments
ZA866905B (en) New catechol derivatives,a process of preparation thereof,and therapeutical compositions containing the same