ZA896150B - The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseases - Google Patents
The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseasesInfo
- Publication number
- ZA896150B ZA896150B ZA896150A ZA896150A ZA896150B ZA 896150 B ZA896150 B ZA 896150B ZA 896150 A ZA896150 A ZA 896150A ZA 896150 A ZA896150 A ZA 896150A ZA 896150 B ZA896150 B ZA 896150B
- Authority
- ZA
- South Africa
- Prior art keywords
- prophylaxis
- alpha
- treatment
- acid derivatives
- boronic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/553—Renin inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3827340A DE3827340A1 (de) | 1988-08-12 | 1988-08-12 | Verwendung von (alpha)-aminoboronsaeure-derivaten zur prophylaxe und behandlung von viruserkrankungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA896150B true ZA896150B (en) | 1991-01-30 |
Family
ID=6360676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA896150A ZA896150B (en) | 1988-08-12 | 1989-08-11 | The use of alpha-amino boronic acid derivatives for the prophylaxis and treatment of virus diseases |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0354522A1 (xx) |
JP (1) | JPH0291023A (xx) |
KR (1) | KR900002766A (xx) |
AU (1) | AU3951389A (xx) |
DE (1) | DE3827340A1 (xx) |
DK (1) | DK395789A (xx) |
IL (1) | IL91276A0 (xx) |
NO (1) | NO893240L (xx) |
PT (1) | PT91426A (xx) |
ZA (1) | ZA896150B (xx) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5142056A (en) * | 1989-05-23 | 1992-08-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
EP0315574A3 (de) * | 1987-11-05 | 1990-08-22 | Hoechst Aktiengesellschaft | Renin-Inhibitoren |
US4983589A (en) * | 1989-12-14 | 1991-01-08 | Chevron Research And Technology Company | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof |
GB9017694D0 (en) * | 1990-08-13 | 1990-09-26 | Sandoz Ltd | Improvements in or relating to organic chemistry |
GB9024775D0 (en) * | 1990-11-14 | 1991-01-02 | Axis Research | Chemical compounds |
US5554728A (en) * | 1991-07-23 | 1996-09-10 | Nexstar Pharmaceuticals, Inc. | Lipid conjugates of therapeutic peptides and protease inhibitors |
DE4126485A1 (de) * | 1991-08-10 | 1993-02-11 | Bayer Ag | Trifluormethyl-haltige pseudopeptide |
US5693617A (en) * | 1994-03-15 | 1997-12-02 | Proscript, Inc. | Inhibitors of the 26s proteolytic complex and the 20s proteasome contained therein |
US6083903A (en) | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
DE4441483C1 (de) * | 1994-11-22 | 1996-04-04 | Gsf Forschungszentrum Umwelt | Verwendung von bio-assimilierbaren Borverbindungen |
US7576206B2 (en) | 2003-08-14 | 2009-08-18 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
US7223745B2 (en) | 2003-08-14 | 2007-05-29 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
US7468383B2 (en) | 2005-02-11 | 2008-12-23 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
US7442830B1 (en) | 2007-08-06 | 2008-10-28 | Millenium Pharmaceuticals, Inc. | Proteasome inhibitors |
US7838673B2 (en) | 2007-10-16 | 2010-11-23 | Millennium Pharmaceuticals, Inc. | Proteasome inhibitors |
SG194349A1 (en) | 2008-06-17 | 2013-11-29 | Millennium Pharm Inc | Boronate ester compounds and pharmaceutical compositions thereof |
AR075090A1 (es) | 2008-09-29 | 2011-03-09 | Millennium Pharm Inc | Derivados de acido 1-amino-2-ciclobutiletilboronico inhibidores de proteosoma,utiles como agentes anticancerigenos, y composiciones farmaceuticas que los comprenden. |
CA2785300A1 (en) | 2009-12-22 | 2011-07-21 | Cephalon, Inc. | Proteasome inhibitors and processes for their preparation, purification and use |
MA34133B1 (fr) * | 2010-03-01 | 2013-04-03 | Onyx Therapeutics Inc | Composes pour inhibiteurs de l'immunoproteasome |
NZ602622A (en) | 2010-03-31 | 2015-01-30 | Millennium Pharm Inc | Derivatives of 1-amino-2-cyclopropylethylboronic acid |
CN103483363B (zh) * | 2012-06-13 | 2016-12-21 | 上海赛迦化工产品有限公司 | 多样性的手性氨基硼酸及其制备方法和应用 |
CN103408572B (zh) * | 2013-07-12 | 2015-12-02 | 上海工程技术大学 | 手性氨基硼酸衍生物及其制备方法和应用 |
CN103396426B (zh) * | 2013-07-12 | 2016-09-28 | 上海工程技术大学 | 手性硼酸衍生物及其制备方法和应用 |
JP2017524652A (ja) | 2014-05-20 | 2017-08-31 | ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. | 一次癌療法後に使用するためのホウ素含有プロテアソーム阻害剤 |
DK3472149T3 (da) | 2016-06-21 | 2023-11-27 | Orion Ophthalmology LLC | Heterocykliske prolinamidderivater |
JP7164521B2 (ja) | 2016-06-21 | 2022-11-01 | オリオン・オフサルモロジー・エルエルシー | 炭素環式プロリンアミド誘導体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4537773A (en) * | 1983-12-05 | 1985-08-27 | E. I. Du Pont De Nemours And Company | α-Aminoboronic acid derivatives |
US4499082A (en) * | 1983-12-05 | 1985-02-12 | E. I. Du Pont De Nemours And Company | α-Aminoboronic acid peptides |
US5187157A (en) * | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
EP0315574A3 (de) * | 1987-11-05 | 1990-08-22 | Hoechst Aktiengesellschaft | Renin-Inhibitoren |
-
1988
- 1988-08-12 DE DE3827340A patent/DE3827340A1/de not_active Withdrawn
-
1989
- 1989-08-08 EP EP89114601A patent/EP0354522A1/de not_active Withdrawn
- 1989-08-10 IL IL91276A patent/IL91276A0/xx unknown
- 1989-08-10 PT PT91426A patent/PT91426A/pt unknown
- 1989-08-11 AU AU39513/89A patent/AU3951389A/en not_active Abandoned
- 1989-08-11 DK DK395789A patent/DK395789A/da not_active Application Discontinuation
- 1989-08-11 NO NO89893240A patent/NO893240L/no unknown
- 1989-08-11 ZA ZA896150A patent/ZA896150B/xx unknown
- 1989-08-11 JP JP1207061A patent/JPH0291023A/ja active Pending
- 1989-08-12 KR KR1019890011499A patent/KR900002766A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE3827340A1 (de) | 1990-02-15 |
DK395789A (da) | 1990-02-13 |
NO893240D0 (no) | 1989-08-11 |
KR900002766A (ko) | 1990-03-31 |
PT91426A (pt) | 1990-03-08 |
AU3951389A (en) | 1990-03-29 |
IL91276A0 (en) | 1990-03-19 |
NO893240L (no) | 1990-03-27 |
DK395789D0 (da) | 1989-08-11 |
EP0354522A1 (de) | 1990-02-14 |
JPH0291023A (ja) | 1990-03-30 |
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