AU3951389A - The use of alpha-amino boronicacid derivatives for the prophylaxis and treatment of virus diseases - Google Patents

The use of alpha-amino boronicacid derivatives for the prophylaxis and treatment of virus diseases

Info

Publication number
AU3951389A
AU3951389A AU39513/89A AU3951389A AU3951389A AU 3951389 A AU3951389 A AU 3951389A AU 39513/89 A AU39513/89 A AU 39513/89A AU 3951389 A AU3951389 A AU 3951389A AU 3951389 A AU3951389 A AU 3951389A
Authority
AU
Australia
Prior art keywords
boronicacid
prophylaxis
alpha
derivatives
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU39513/89A
Inventor
Heinz-Werner Kleemann
Wolfgang Konig
Karin Molling
Arnold Paessens
Dieter Ruppert
Hansjorg Urbach
Irvin Winkler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU3951389A publication Critical patent/AU3951389A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/553—Renin inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU39513/89A 1988-08-12 1989-08-11 The use of alpha-amino boronicacid derivatives for the prophylaxis and treatment of virus diseases Abandoned AU3951389A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3827340A DE3827340A1 (en) 1988-08-12 1988-08-12 USE OF (ALPHA) -AMINOBORONIC ACID DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF VIRUS DISEASES
DE3827340 1988-08-12

Publications (1)

Publication Number Publication Date
AU3951389A true AU3951389A (en) 1990-03-29

Family

ID=6360676

Family Applications (1)

Application Number Title Priority Date Filing Date
AU39513/89A Abandoned AU3951389A (en) 1988-08-12 1989-08-11 The use of alpha-amino boronicacid derivatives for the prophylaxis and treatment of virus diseases

Country Status (10)

Country Link
EP (1) EP0354522A1 (en)
JP (1) JPH0291023A (en)
KR (1) KR900002766A (en)
AU (1) AU3951389A (en)
DE (1) DE3827340A1 (en)
DK (1) DK395789A (en)
IL (1) IL91276A0 (en)
NO (1) NO893240L (en)
PT (1) PT91426A (en)
ZA (1) ZA896150B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU608379B2 (en) * 1987-11-05 1991-03-28 Hoechst Aktiengesellschaft Renin inhibitors
AU635800B2 (en) * 1989-12-14 1993-04-01 Chevron Research And Technology Company Fungicidal imidazole diphenylaliphaticboranes
AU643312B2 (en) * 1990-08-13 1993-11-11 Novartis Ag Improvements in or relating to organic chemistry
AU666294B2 (en) * 1990-11-14 1996-02-08 Axis Biochemicals Asa Labelling agents comprising boronic acid conjugates
US8859504B2 (en) 2008-06-17 2014-10-14 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US11241448B2 (en) 2014-05-20 2022-02-08 Millennium Pharmaceuticals, Inc. Methods for cancer therapy

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142056A (en) * 1989-05-23 1992-08-25 Abbott Laboratories Retroviral protease inhibiting compounds
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
DE4126485A1 (en) * 1991-08-10 1993-02-11 Bayer Ag TRIFLUOROMETHYL-CONTAINING PSEUDOPEPTIDE
US5693617A (en) * 1994-03-15 1997-12-02 Proscript, Inc. Inhibitors of the 26s proteolytic complex and the 20s proteasome contained therein
US6083903A (en) * 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
DE4441483C1 (en) * 1994-11-22 1996-04-04 Gsf Forschungszentrum Umwelt Use of bio-assimilated boron cpds.
US7223745B2 (en) 2003-08-14 2007-05-29 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7576206B2 (en) 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7468383B2 (en) 2005-02-11 2008-12-23 Cephalon, Inc. Proteasome inhibitors and methods of using the same
US7442830B1 (en) 2007-08-06 2008-10-28 Millenium Pharmaceuticals, Inc. Proteasome inhibitors
US7838673B2 (en) 2007-10-16 2010-11-23 Millennium Pharmaceuticals, Inc. Proteasome inhibitors
AR075090A1 (en) 2008-09-29 2011-03-09 Millennium Pharm Inc ACID DERIVATIVES 1-AMINO-2-CYCLLOBUTILETILBORONICO PROTEOSOMA INHIBITORS, USEFUL AS ANTI-BANKER AGENTS, AND PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM.
EP2516449A1 (en) 2009-12-22 2012-10-31 Cephalon, Inc. Proteasome inhibitors and processes for their preparation, purification and use
US9359398B2 (en) * 2010-03-01 2016-06-07 Onyx Therapeutics, Inc. Compounds for immunoproteasome inhibition
US8513218B2 (en) 2010-03-31 2013-08-20 Millennium Pharmaceuticals, Inc. Derivatives of 1-amino-2-cyclopropylethylboronic acid
CN103483363B (en) * 2012-06-13 2016-12-21 上海赛迦化工产品有限公司 Multifarious chiral aminoboronic acid and its preparation method and application
CN103396426B (en) * 2013-07-12 2016-09-28 上海工程技术大学 Chirality boronic acid derivatives and its preparation method and application
CN103408572B (en) * 2013-07-12 2015-12-02 上海工程技术大学 Chiral aminoboronic acid derivative and its preparation method and application
JP7164521B2 (en) 2016-06-21 2022-11-01 オリオン・オフサルモロジー・エルエルシー carbocyclic prolinamide derivatives
EP4257191A3 (en) 2016-06-21 2023-11-22 Orion Ophthalmology LLC Heterocyclic prolinamide derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4537773A (en) * 1983-12-05 1985-08-27 E. I. Du Pont De Nemours And Company α-Aminoboronic acid derivatives
US4499082A (en) * 1983-12-05 1985-02-12 E. I. Du Pont De Nemours And Company α-Aminoboronic acid peptides
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
EP0315574A3 (en) * 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin inhibitors

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU608379B2 (en) * 1987-11-05 1991-03-28 Hoechst Aktiengesellschaft Renin inhibitors
AU635800B2 (en) * 1989-12-14 1993-04-01 Chevron Research And Technology Company Fungicidal imidazole diphenylaliphaticboranes
AU643312B2 (en) * 1990-08-13 1993-11-11 Novartis Ag Improvements in or relating to organic chemistry
AU666294B2 (en) * 1990-11-14 1996-02-08 Axis Biochemicals Asa Labelling agents comprising boronic acid conjugates
US8859504B2 (en) 2008-06-17 2014-10-14 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US9175018B2 (en) 2008-06-17 2015-11-03 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US9175017B2 (en) 2008-06-17 2015-11-03 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US10526351B2 (en) 2008-06-17 2020-01-07 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US10604538B2 (en) 2008-06-17 2020-03-31 Millenium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US11485746B2 (en) 2008-06-17 2022-11-01 Millennium Pharmaceuticals, Inc. Boronate ester compounds and pharmaceutical compositions thereof
US11241448B2 (en) 2014-05-20 2022-02-08 Millennium Pharmaceuticals, Inc. Methods for cancer therapy

Also Published As

Publication number Publication date
KR900002766A (en) 1990-03-31
JPH0291023A (en) 1990-03-30
ZA896150B (en) 1991-01-30
DE3827340A1 (en) 1990-02-15
EP0354522A1 (en) 1990-02-14
IL91276A0 (en) 1990-03-19
DK395789D0 (en) 1989-08-11
DK395789A (en) 1990-02-13
NO893240L (en) 1990-03-27
NO893240D0 (en) 1989-08-11
PT91426A (en) 1990-03-08

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