ZA895969B - Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
ZA895969B
ZA895969B ZA895969A ZA895969A ZA895969B ZA 895969 B ZA895969 B ZA 895969B ZA 895969 A ZA895969 A ZA 895969A ZA 895969 A ZA895969 A ZA 895969A ZA 895969 B ZA895969 B ZA 895969B
Authority
ZA
South Africa
Prior art keywords
processes
pharmaceutical compositions
alkoxy
compositions containing
preparation
Prior art date
Application number
ZA895969A
Other languages
English (en)
Inventor
Julian Aranda
Johannes Hartenstein
Reinhard Reck
Christopher Schaechtele
Claus Rudolph
Hartmut Osswald
Guenter Weinheimer
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of ZA895969B publication Critical patent/ZA895969B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
ZA895969A 1988-08-06 1989-08-04 Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing them ZA895969B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3826846A DE3826846A1 (de) 1988-08-06 1988-08-06 Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA895969B true ZA895969B (en) 1990-05-30

Family

ID=6360419

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895969A ZA895969B (en) 1988-08-06 1989-08-04 Alkoxy-4(1h)-pyridone derivatives,processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (18)

Country Link
US (2) US5185352A (zh)
EP (2) EP0354495A1 (zh)
JP (1) JP2878361B2 (zh)
KR (1) KR920006779B1 (zh)
CN (1) CN1040193A (zh)
AT (1) ATE188469T1 (zh)
AU (1) AU627766B2 (zh)
CA (1) CA1340608C (zh)
DD (1) DD284003A5 (zh)
DE (2) DE3826846A1 (zh)
DK (1) DK174097B1 (zh)
ES (1) ES2144391T3 (zh)
GR (1) GR3033072T3 (zh)
HU (1) HUT56545A (zh)
NO (1) NO177785C (zh)
PT (1) PT91351B (zh)
WO (1) WO1990001477A1 (zh)
ZA (1) ZA895969B (zh)

Families Citing this family (30)

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US4822786A (en) * 1986-07-01 1989-04-18 Kaken Pharmaceutical Co., Ltd. Cephalosporin compounds, and antibacterial agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
FR2687674B1 (fr) * 1992-02-07 1995-05-19 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
US5674883A (en) * 1992-02-07 1997-10-07 Roussel Uclaf Derivatives of pyridone, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them
DE4243321A1 (de) * 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
US6046219A (en) * 1995-01-20 2000-04-04 Cornell Research Foundation, Inc. Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
JP2002531511A (ja) * 1998-12-07 2002-09-24 エコスマート テクノロジーズ，インコーポレーテッド シグナル伝達調節物質と天然植物精油を用いた癌治療薬配合物および方法
US6716838B1 (en) 1999-05-19 2004-04-06 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents
US6653316B1 (en) 1999-05-19 2003-11-25 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
US6906068B1 (en) 1999-05-19 2005-06-14 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl 1,2,4 - triazinones useful as anticoagulants
US6664255B1 (en) 1999-05-19 2003-12-16 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade
US6867217B1 (en) 1999-05-19 2005-03-15 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade
US6750342B1 (en) 1999-05-19 2004-06-15 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyrimidinones useful for selective inhibition of the coagulation cascade
US7015230B1 (en) 1999-05-19 2006-03-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl uracils useful for selective inhibition of the coagulation cascade
WO2001068605A1 (en) 2000-03-13 2001-09-20 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
US20020022604A1 (en) 2000-04-05 2002-02-21 South Michael S. Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade
EP1268428A2 (en) 2000-04-05 2003-01-02 Pharmacia Corporation Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade
US7015223B1 (en) 2000-11-20 2006-03-21 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl 1,2,4-triazinones useful for selective inhibition of the coagulation cascade
US7119094B1 (en) 2000-11-20 2006-10-10 Warner-Lambert Company Substituted polycyclic aryl and heteroarpyl pyrazinones useful for selective inhibition of the coagulation cascade
WO2002042272A2 (en) 2000-11-20 2002-05-30 Pharmacia Corporation Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade
EP1438292A1 (en) 2001-10-03 2004-07-21 Pharmacia Corporation 6-membered heterocyclic compounds useful for selective inhibition of the coagulation cascade
BR0213099A (pt) 2001-10-03 2004-10-19 Pharmacia Corp Compostos policìclicos de 5 membros substituìdos úteis para inibição seletiva da cascata de coagulação
UY30986A1 (es) 2007-03-28 2008-09-02 Apotex Technologies Inc Derivados fluorinados de deferiprona
UA102254C2 (ru) 2008-04-25 2013-06-25 Апотекс Технолоджис Инк. Жидкий состав для деферипрона с приятным вкусом
MX345942B (es) * 2009-05-01 2017-02-27 Adare Pharmaceuticals Inc Composiciones de tabletas que se desintegran oralmente que comprenden combinaciones de farmacos en dosis alta y baja.
ES2524342T3 (es) 2009-07-03 2014-12-05 Apotex Technologies Inc. Derivados fluorados de 3-hidroxipiridin-4-unos
DK3287443T3 (da) 2015-04-24 2022-02-07 Shionogi & Co 6-leddet heterocyklisk derivat og farmaceutisk sammensætning, som omfatter dette
JP6692113B2 (ja) * 2016-10-21 2020-05-13 塩野義製薬株式会社 ６員複素環誘導体を含有する医薬組成物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA554715A (en) * 1958-03-18 Boesch Roger Ethers and thioethers and processes for their preparation
US2965641A (en) * 1959-07-06 1960-12-20 Searle & Co Derivatives of 1-(2-aminoethyl)-5-alkoxy-4-pyridones
CA978958A (en) * 1971-10-04 1975-12-02 Haydn W.R. Williams Substituted pyranones and -pyridones and process of manufacture
JPS59110675A (ja) * 1982-12-16 1984-06-26 Ss Pharmaceut Co Ltd ピリジン誘導体及びその製造方法
JPS59110674A (ja) * 1982-12-16 1984-06-26 Ss Pharmaceut Co Ltd ピリジン誘導体及びその製造法
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
US4822786A (en) * 1986-07-01 1989-04-18 Kaken Pharmaceutical Co., Ltd. Cephalosporin compounds, and antibacterial agents
DE3826846A1 (de) * 1988-08-06 1990-02-08 Goedecke Ag Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
JP2878361B2 (ja) 1999-04-05
PT91351B (pt) 1997-01-31
DK11391D0 (da) 1991-01-23
CA1340608C (en) 1999-06-22
ATE188469T1 (de) 2000-01-15
GR3033072T3 (en) 2000-08-31
AU4048989A (en) 1990-03-05
DK174097B1 (da) 2002-06-10
HU894581D0 (en) 1991-07-29
DE3826846A1 (de) 1990-02-08
NO177785B (no) 1995-08-14
WO1990001477A1 (de) 1990-02-22
CN1040193A (zh) 1990-03-07
DK11391A (da) 1991-01-23
NO910444D0 (no) 1991-02-05
NO910444L (no) 1991-02-05
HUT56545A (en) 1991-09-30
EP0427765A1 (de) 1991-05-22
KR900701755A (ko) 1990-12-04
EP0354495A1 (de) 1990-02-14
KR920006779B1 (ko) 1992-08-17
US5322844A (en) 1994-06-21
JPH04500958A (ja) 1992-02-20
ES2144391T3 (es) 2000-06-16
PT91351A (pt) 1990-03-08
DE58909865D1 (de) 2000-02-10
EP0427765B1 (de) 2000-01-05
NO177785C (no) 1995-11-22
AU627766B2 (en) 1992-09-03
DD284003A5 (de) 1990-10-31
US5185352A (en) 1993-02-09

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