ZA895797B - Memory enhancing-r-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamides - Google Patents
Memory enhancing-r-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamidesInfo
- Publication number
- ZA895797B ZA895797B ZA895797A ZA895797A ZA895797B ZA 895797 B ZA895797 B ZA 895797B ZA 895797 A ZA895797 A ZA 895797A ZA 895797 A ZA895797 A ZA 895797A ZA 895797 B ZA895797 B ZA 895797B
- Authority
- ZA
- South Africa
- Prior art keywords
- thiobenzamides
- benzamides
- azabicyclo
- oct
- memory enhancing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88402041A EP0353371A1 (en) | 1988-08-04 | 1988-08-04 | Memory enhancing-R-N-(1-azabicyclo[2.2.2] oct-3-yl) benzamides and thiobenzamides |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA895797B true ZA895797B (en) | 1991-03-27 |
Family
ID=8200414
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA895797A ZA895797B (en) | 1988-08-04 | 1989-07-28 | Memory enhancing-r-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamides |
Country Status (10)
Country | Link |
---|---|
US (1) | US5017580A (xx) |
EP (1) | EP0353371A1 (xx) |
JP (1) | JPH02256616A (xx) |
KR (1) | KR900002778A (xx) |
AU (1) | AU624402B2 (xx) |
CA (1) | CA1333154C (xx) |
DK (1) | DK381889A (xx) |
PH (1) | PH25427A (xx) |
PT (1) | PT91346B (xx) |
ZA (1) | ZA895797B (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3878235T2 (de) * | 1988-08-04 | 1993-06-03 | Synthelabo | Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide. |
EP0527249B1 (en) * | 1991-08-09 | 1997-12-17 | Nec Corporation | Carrier recovery apparatus for digital satellite communication system |
US5273972A (en) * | 1992-03-26 | 1993-12-28 | A. H. Robins Company, Incorporated | [(2-diakylaminomethyl)-3-quinuclidinyl]-benzamides and benzoates |
US5723103A (en) * | 1994-12-09 | 1998-03-03 | Vanderbilt University | Substituted benzamides and radioligand analogs and methods of use |
US6486172B2 (en) | 2000-08-18 | 2002-11-26 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
WO2002016356A2 (en) * | 2000-08-18 | 2002-02-28 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
US6492385B2 (en) | 2000-08-18 | 2002-12-10 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
AU2001282874A1 (en) | 2000-08-18 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands) |
US6500840B2 (en) | 2000-08-21 | 2002-12-31 | Pharmacia & Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
AU2001284646A1 (en) | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
PE20021019A1 (es) * | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
WO2003018586A1 (en) * | 2001-08-24 | 2003-03-06 | Pharmacia & Upjohn Company | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease |
JP2005510482A (ja) * | 2001-10-16 | 2005-04-21 | アストラゼネカ・アクチエボラーグ | 線維筋痛症候群の治療方法 |
BR0214031A (pt) * | 2001-11-08 | 2004-10-19 | Upjohn Co | Compostos de heteroarila azabicìclico substituìdos para o tratamento de doenças |
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
BR0307714A (pt) * | 2002-02-15 | 2005-02-09 | Upjohn Co | Benzoilamidas substituìdas com azabiciclo e tioamidas para tratamento de distúrbios relacionados ao cns |
BR0307874A (pt) * | 2002-02-20 | 2004-12-28 | Upjohn Co | Atividade de compostos azabicìclicos com receptor de acetilcolina nicotìnica alfa7 |
WO2004013137A1 (en) | 2002-08-01 | 2004-02-12 | Pharmacia & Upjohn Company Llc | 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity |
GB0310867D0 (en) | 2003-05-12 | 2003-06-18 | Novartis Ag | Organic compounds |
US8435762B2 (en) | 2008-10-09 | 2013-05-07 | Howard Hughes Medical Institute | Chimeric ligand-gated ion channels and methods of use thereof |
EP2540297B1 (en) | 2008-11-19 | 2015-04-08 | Forum Pharmaceuticals Inc. | Treatment of Cognitive Disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof |
CN105837566B (zh) | 2010-05-17 | 2018-02-06 | 富瑞姆制药公司 | (R)‑7‑氯‑N‑(奎宁环‑3‑基)苯并[b]噻吩‑2‑甲酰胺盐酸盐单水合物的晶型 |
EP2846796A4 (en) | 2012-05-08 | 2015-10-21 | Forum Pharmaceuticals Inc | METHODS OF MAINTAINING, PROCESSING OR ENHANCING COGNITIVE FUNCTION |
CN104418851A (zh) * | 2013-09-02 | 2015-03-18 | 上海龙翔生物医药开发有限公司 | 奎宁环衍生物的制备方法及纯化方法 |
US10370369B2 (en) * | 2015-03-31 | 2019-08-06 | Yuki Gosei Kogyo Co. Ltd. | Acid addition salt of 3-aminoquinuclidine which does not exhibit deliquescence |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4605652A (en) * | 1985-02-04 | 1986-08-12 | A. H. Robins Company, Inc. | Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes |
DE3878235T2 (de) * | 1988-08-04 | 1993-06-03 | Synthelabo | Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.)oct-3-yl)benzamide und thiobenzamide. |
-
1988
- 1988-08-04 EP EP88402041A patent/EP0353371A1/en not_active Withdrawn
-
1989
- 1989-07-28 ZA ZA895797A patent/ZA895797B/xx unknown
- 1989-08-01 AU AU39174/89A patent/AU624402B2/en not_active Ceased
- 1989-08-01 PH PH39033A patent/PH25427A/en unknown
- 1989-08-02 PT PT91346A patent/PT91346B/pt not_active IP Right Cessation
- 1989-08-03 US US07/389,309 patent/US5017580A/en not_active Expired - Fee Related
- 1989-08-03 DK DK381889A patent/DK381889A/da not_active Application Discontinuation
- 1989-08-04 CA CA000607650A patent/CA1333154C/en not_active Expired - Fee Related
- 1989-08-04 JP JP1202710A patent/JPH02256616A/ja active Pending
- 1989-08-04 KR KR1019890011229A patent/KR900002778A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DK381889D0 (da) | 1989-08-03 |
PT91346A (pt) | 1990-03-08 |
PT91346B (pt) | 1995-07-03 |
EP0353371A1 (en) | 1990-02-07 |
JPH02256616A (ja) | 1990-10-17 |
CA1333154C (en) | 1994-11-22 |
DK381889A (da) | 1990-02-05 |
AU624402B2 (en) | 1992-06-11 |
US5017580A (en) | 1991-05-21 |
AU3917489A (en) | 1990-02-08 |
KR900002778A (ko) | 1990-03-23 |
PH25427A (en) | 1991-07-01 |
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