ZA894828B - Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity - Google Patents

Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity

Info

Publication number
ZA894828B
ZA894828B ZA894828A ZA894828A ZA894828B ZA 894828 B ZA894828 B ZA 894828B ZA 894828 A ZA894828 A ZA 894828A ZA 894828 A ZA894828 A ZA 894828A ZA 894828 B ZA894828 B ZA 894828B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical agents
ibuprofen
throat
elimination
burning
Prior art date
Application number
ZA894828A
Other languages
English (en)
Inventor
Mario Carcano
Carcano Mario
Massimo Costa
Costa Massimo
Original Assignee
Aesculapius Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4238447&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA894828(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aesculapius Pharma Sa filed Critical Aesculapius Pharma Sa
Publication of ZA894828B publication Critical patent/ZA894828B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA894828A 1988-07-12 1989-06-26 Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity ZA894828B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2647/88A CH677606A5 (da) 1988-07-12 1988-07-12

Publications (1)

Publication Number Publication Date
ZA894828B true ZA894828B (en) 1990-03-28

Family

ID=4238447

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894828A ZA894828B (en) 1988-07-12 1989-06-26 Process for the preparation of anti-inflammatory pharmaceutical agents with an ibuprofen base,with elimination,in solution,of the bitter taste,burning of the throat and intestinal toxicity

Country Status (11)

Country Link
US (1) US5180590A (da)
EP (1) EP0351353B1 (da)
JP (1) JPH07112973B2 (da)
AT (1) ATE73656T1 (da)
CA (1) CA1336323C (da)
CH (1) CH677606A5 (da)
DE (1) DE68901014D1 (da)
DK (1) DK342989A (da)
ES (1) ES2032681T3 (da)
GR (1) GR3004148T3 (da)
ZA (1) ZA894828B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814337A (en) * 1992-10-07 1998-09-29 Beecham Group Plc Pharmaceutical formulation
US6525214B1 (en) 1991-05-13 2003-02-25 Bernard John Armitage Therapeutic agent
FR2698788B1 (fr) * 1992-12-09 1995-03-03 Union Pharma Scient Appl Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.
GB9316580D0 (en) * 1993-08-10 1993-09-29 Smithkline Beecham Plc Pharmaceutical composition
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
GB9426196D0 (en) * 1994-12-23 1995-02-22 Procter & Gamble Processes of preparing pharmaceutical compositions
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
ES2142601T3 (es) * 1995-07-31 2000-04-16 Gerhard Gergely Comprimido masticable con accion efervescente.
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
NZ333474A (en) 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
US20050176599A1 (en) * 2000-11-09 2005-08-11 Bergquist Catharine J. Controlled delivery system for household products
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
US20080085308A1 (en) * 2004-08-12 2008-04-10 Reckitt Benckiser Healthcare (Uk) Limited Granules Comprising Paracetamol, a Nsaid and a Sugar Alchohol Made by Melt Extrusion
EP1942877A4 (en) * 2005-11-02 2011-09-14 Teikoku Pharma Usa Inc ORGANOLEPTICALLY ACCEPTABLE ORAL DOSAGE FORMS OF IBUPROFEN, MANUFACTURING METHOD AND APPLICATION
EP1905428A1 (de) * 2006-09-26 2008-04-02 Losan Pharma GmbH Ibuprofen-Brausezubereitung mit hoher Lösungsgeschwindigkeit und Verfahren zu deren Herstellung
TR200900881A2 (tr) * 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tadı ve kokusu maskelenmiş stabil farmasötik bileşimler
US20140163109A1 (en) 2012-03-26 2014-06-12 Glatt Ag Taste-masked ibupropen granules
EP2913049B1 (en) 2014-02-27 2016-11-30 Galenicum Health S.L. Stable pharmaceutical compositions
EP3157506B1 (en) * 2014-06-20 2020-08-26 Hermes Arzneimittel GmbH Taste-masked oral pharmaceutical composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE59106B1 (en) * 1985-05-31 1994-01-12 Warner Lambert Co A therapeutic effervescent composition and a method of preparing the same
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
GB8528195D0 (en) * 1985-11-15 1985-12-18 Boots Co Plc Therapeutic compositions
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations

Also Published As

Publication number Publication date
DK342989A (da) 1990-01-13
ES2032681T3 (es) 1993-02-16
JPH0272115A (ja) 1990-03-12
CA1336323C (en) 1995-07-18
EP0351353A1 (en) 1990-01-17
ATE73656T1 (de) 1992-04-15
EP0351353B1 (en) 1992-03-18
GR3004148T3 (da) 1993-03-31
JPH07112973B2 (ja) 1995-12-06
DK342989D0 (da) 1989-07-11
DE68901014D1 (de) 1992-04-23
US5180590A (en) 1993-01-19
CH677606A5 (da) 1991-06-14

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