ZA891761B - Alkoxy-and alkylamino-carbonylalkylphospholipids,a process for their preparation and their use as medicaments - Google Patents

Alkoxy-and alkylamino-carbonylalkylphospholipids,a process for their preparation and their use as medicaments

Info

Publication number
ZA891761B
ZA891761B ZA891761A ZA891761A ZA891761B ZA 891761 B ZA891761 B ZA 891761B ZA 891761 A ZA891761 A ZA 891761A ZA 891761 A ZA891761 A ZA 891761A ZA 891761 B ZA891761 B ZA 891761B
Authority
ZA
South Africa
Prior art keywords
carbonylalkylphospholipids
medicaments
alkylamino
alkoxy
preparation
Prior art date
Application number
ZA891761A
Other languages
English (en)
Inventor
Nicolas J Hrib
J Hrib Nicolas
Kirk David Shoger
David Shoger Kirk
John Joseph Tegeler
Joseph Tegeler John
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of ZA891761B publication Critical patent/ZA891761B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
    • C07F9/6544—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533—Six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA891761A 1988-03-10 1989-03-08 Alkoxy-and alkylamino-carbonylalkylphospholipids,a process for their preparation and their use as medicaments ZA891761B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/166,285 US4888328A (en) 1988-03-10 1988-03-10 Alkoxycarbonylalkylphospholipids and alkylaminocarbonylalkylphospholipids

Publications (1)

Publication Number Publication Date
ZA891761B true ZA891761B (en) 1990-04-25

Family

ID=22602614

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891761A ZA891761B (en) 1988-03-10 1989-03-08 Alkoxy-and alkylamino-carbonylalkylphospholipids,a process for their preparation and their use as medicaments

Country Status (8)

Country Link
US (1) US4888328A (ja)
EP (1) EP0332129A2 (ja)
JP (1) JPH024793A (ja)
KR (1) KR890014566A (ja)
AU (1) AU3113489A (ja)
DK (1) DK114589A (ja)
PT (1) PT89966A (ja)
ZA (1) ZA891761B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030733A (en) * 1987-07-23 1991-07-09 Hoechst-Roussel Pharmaceticals Incorporated Hydroxy-, alkoxy- and benzyloxy-substituted phospholipids
GB9004881D0 (en) * 1990-03-05 1990-05-02 Biocompatibles Ltd Method of improving the ocular of synthetic polymers haemo and biocompatibility
DE69126440T2 (de) * 1990-11-05 1997-09-18 Biocompatibles Ltd Phosphorsäureester und ihre verwendung zur herstellung biokompatibler oberflächen
US5661138A (en) * 1996-10-03 1997-08-26 Clarion Pharmaceutical, Inc. (o-Acyl-p-N-acylamino-phenyl)-O-phosphoethanolamines
ES2618482T3 (es) 2007-08-10 2017-06-21 Basil Rigas Compuestos antiinflamatorios y usos de los mismos

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2009342C3 (de) * 1970-02-27 1980-12-18 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verwendung von Glycerin-alkyläther-(l)-phosphorsäure-(3)-monocholinestern
US4119714A (en) * 1970-02-27 1978-10-10 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. Glycerin-alkylether-(1)-phosphoric acid-(3)-monocholine esters as enhancers of the natural resistance of the mammalian organism against non-carcinogenic pathogens
DE2009341C3 (de) * 1970-02-27 1979-06-21 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen 3-Octadecyloxy-propanol-(l)-phosphorsäure-monocholinester und Verfahren zu dessen Herstellung
US4163748A (en) * 1973-09-06 1979-08-07 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Propane-1,3-diol phosphatides and method of preparing the same
US4159988A (en) * 1974-08-06 1979-07-03 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Synthetic phospholipids, a process for their manufacture and their use
DE2619686C2 (de) * 1976-05-04 1986-08-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verwendung eines Lysolecithins zur Tumorbehandlung
DE2619715A1 (de) * 1976-05-04 1977-11-24 Max Planck Gesellschaft Tumor-antigen und verfahren zu dessen herstellung
DD138216A1 (de) * 1978-08-03 1979-10-17 Hans Brachwitz Verfahren zur herstellung von fluoranaloga der 1-und 2-0-alkyl-bzw.1-und 2-0-acyl-glycero-3-phosphocholine
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
US4551532A (en) * 1980-05-08 1985-11-05 Takeda Chemical Industries, Ltd. Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity
DE3127503A1 (de) * 1981-07-11 1983-02-17 Boehringer Mannheim Gmbh, 6800 Mannheim Neue phospholipide, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
AU3113489A (en) 1989-09-14
KR890014566A (ko) 1989-10-24
US4888328A (en) 1989-12-19
JPH024793A (ja) 1990-01-09
DK114589A (da) 1989-09-11
DK114589D0 (da) 1989-03-09
PT89966A (pt) 1989-11-10
EP0332129A2 (en) 1989-09-13

Similar Documents

Publication Publication Date Title
ZA907174B (en) 3-(1-substituted-4-piperazinyl)-1h-indazoles,a process for their preparation and their use as medicaments
ZA904997B (en) Heteroarylamino-and heteroaryloxypridinamines and related compounds,a process for their preparation and their use as medicaments
ZA898858B (en) New quinuclidines,their use as medicaments and processes for their preparation
ZA881865B (en) Substituted 9-amino-tetrahydroacridines and related compounds,a process for their preparation and their use as medicaments
IL94320A0 (en) N-heteroaryl-4-quinolinamines,a process for their preparation and their use as medicaments
DE3662104D1 (en) 4'-demethyl-4-epipodophyllotoxin derivatives, a process for their preparation and their use as medicaments
IL83152A0 (en) 7-acyloxy-6-aminoacyloxypolyoxylabdanes,a process for their preparation,and their use as medicaments
IL71856A0 (en) Dibenzodiazepin derivatives,a process for their preparation and their use as medicaments
ZA89154B (en) Pyrazol-and indazolpyridin amines,a process for their preparation and their use as medicaments
ZA891761B (en) Alkoxy-and alkylamino-carbonylalkylphospholipids,a process for their preparation and their use as medicaments
IL96782A0 (en) Aminopyridinylmethanols and aminomethylpyridinamines and related compounds,a process for their preparation and their use as medicaments
ZA893374B (en) Hydrazinocarbonyloxylabdanes,a process for their preparation and their use as medicaments
ZA856775B (en) Histargin-related compounds,a process for their preparation and their use as medicaments
ZA905045B (en) Phenoxypyridinamines and related compounds,a process for their preparation and their use as medicaments
ZA898638B (en) 1-aminoalkyl-3-oxysubstituted-4-aryl-1,3,4,5-tetrahydro-2h-1 3-benzodiazepine-2-ones,a process for their preparation and their use as medicaments
ZA866444B (en) Spergualin-related compounds,a process for their preparation and their use as medicaments
ZA855584B (en) New combination product,a process for its preparation and its use as a medicament
PT81880A (en) (1,2,4-oxadiazol-3-yl)-arymethanones a process for their preparation and their use as medicaments
IL84987A0 (en) Nitrohaloalkoxybenzenes,a process for their preparation,and their use
NZ220805A (en) Cytorhodin s derivatives,a process for their preparation and their use as medicaments
ZA888194B (en) New acyllabdane derivatives,a process for their preparation,and their use as medicaments
IL94221A0 (en) Tetrahydroisoquino(2,1,c)(1,3)-benzodiazepines,a process for their preparation and their use as medicaments
IL96771A0 (en) Thienobenzoxepin-and naphthothiophene-derivatives,a process and intermediates for their preparation and their use as medicaments
ZA9010328B (en) Aminopyridinylmethanols and aminomethylpyridinamines and related compounds,a process for their preparation and their use as medicaments
PT82446A (en) (aminoalkylthio) hydroxybenzoxepins a process for their preparation and their use as medicaments