ZA88896B - Pyridine-2,4-and-2,5-dicarboxylic acid amides,processes for their preparation,the use thereof,and medicaments based on these compounds - Google Patents
Pyridine-2,4-and-2,5-dicarboxylic acid amides,processes for their preparation,the use thereof,and medicaments based on these compoundsInfo
- Publication number
- ZA88896B ZA88896B ZA880896A ZA88896A ZA88896B ZA 88896 B ZA88896 B ZA 88896B ZA 880896 A ZA880896 A ZA 880896A ZA 88896 A ZA88896 A ZA 88896A ZA 88896 B ZA88896 B ZA 88896B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridine
- compounds
- processes
- preparation
- dicarboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873703959 DE3703959A1 (de) | 1987-02-10 | 1987-02-10 | Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA88896B true ZA88896B (en) | 1988-08-08 |
Family
ID=6320590
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA880896A ZA88896B (en) | 1987-02-10 | 1988-02-09 | Pyridine-2,4-and-2,5-dicarboxylic acid amides,processes for their preparation,the use thereof,and medicaments based on these compounds |
Country Status (20)
Country | Link |
---|---|
US (1) | US5037839A (pt) |
EP (1) | EP0278453B1 (pt) |
JP (1) | JPH0641450B2 (pt) |
KR (1) | KR960011372B1 (pt) |
AR (1) | AR247732A1 (pt) |
AT (1) | ATE116299T1 (pt) |
AU (1) | AU599746B2 (pt) |
CA (1) | CA1334972C (pt) |
DE (2) | DE3703959A1 (pt) |
DK (1) | DK167804B1 (pt) |
ES (1) | ES2067448T3 (pt) |
FI (1) | FI91525C (pt) |
GR (1) | GR3014958T3 (pt) |
HU (1) | HU205905B (pt) |
IE (1) | IE65348B1 (pt) |
IL (1) | IL85362A (pt) |
NO (1) | NO174420C (pt) |
NZ (1) | NZ223433A (pt) |
PT (1) | PT86736B (pt) |
ZA (1) | ZA88896B (pt) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5519038A (en) * | 1989-07-20 | 1996-05-21 | Hoechst Aktiengesellschaft | N,N'-bis(alkoxyalkyl)-pyridine-2,4-dicarboxylic acid diamines |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5153208A (en) * | 1987-02-10 | 1992-10-06 | Hoechst Aktiengesellschaft | Pyridine-2,4- and -2,5-dicarboxylic acid amides and their medicinal compositions and methods of use |
US5512586A (en) * | 1987-02-10 | 1996-04-30 | Hoechst Aktiengesellschaft | Medicaments based on pyridine-2,4- and 2,5-dicarboxylic acid amides |
DE3707429A1 (de) * | 1987-03-07 | 1988-09-15 | Hoechst Ag | Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
ES2065355T3 (es) * | 1988-08-04 | 1995-02-16 | Hoechst Ag | Procedimiento mejorado para la preparacion de n,n'-bis (alcoxialquil)-diamidas de acidos piridina-2,4-dicarboxilicos. |
DE3924093A1 (de) | 1989-07-20 | 1991-02-07 | Hoechst Ag | N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
DE3928144A1 (de) * | 1989-08-25 | 1991-02-28 | Hoechst Ag | Zyklische pyridin-2,4- und -2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
DE3931432A1 (de) * | 1989-09-21 | 1991-04-04 | Hoechst Ag | Pyrimidin-4,6-dicarbonsaeurediamide, verfahren zu deren herstellung sowie verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
DE3938805A1 (de) * | 1989-11-23 | 1991-05-29 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
ZA91291B (en) * | 1990-01-16 | 1991-09-25 | Hoechst Ag | Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof |
US5260323A (en) * | 1990-06-28 | 1993-11-09 | Hoechst Aktiengesellschaft | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use |
DE4020570A1 (de) | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
DE4031000A1 (de) * | 1990-10-01 | 1992-04-09 | Hoechst Ag | 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
YU9492A (sh) * | 1991-02-05 | 1995-03-27 | Hoechst Ag. | 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje |
TW199147B (pt) * | 1991-03-18 | 1993-02-01 | Hoechst Ag | |
EP0541042A1 (de) * | 1991-11-05 | 1993-05-12 | Hoechst Aktiengesellschaft | Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
EP0548883A1 (de) * | 1991-12-24 | 1993-06-30 | Hoechst Aktiengesellschaft | Substituierte Pyridin-N-oxide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
TW352384B (en) * | 1992-03-24 | 1999-02-11 | Hoechst Ag | Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals |
EP0567997A1 (de) * | 1992-04-30 | 1993-11-03 | Hoechst Aktiengesellschaft | 4- oder 5-(Sulf)imido- und (Sulfon)amidopyridine, sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US5789426A (en) * | 1995-01-20 | 1998-08-04 | Cornell Research Foundation, Inc. | Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation |
US6046219A (en) * | 1995-01-20 | 2000-04-04 | Cornell Research Foundation, Inc. | Method for the treatment of conditions mediated by collagen formation together with cell proliferation by application of inhibitors of protein hydroxylation |
FR2766187B1 (fr) * | 1997-07-17 | 2000-06-02 | Rhone Poulenc Rorer Sa | Derives de pyrazine, leur preparation et les medicaments les contenant |
JP2003522093A (ja) * | 1997-10-24 | 2003-07-22 | ファイブロゲン インコーポレイテッド | フェナントロリン誘導体 |
EP1932834B1 (en) * | 2006-12-11 | 2011-04-27 | The Genetics Company, Inc. | Aromatic 1,4-DI-Carboxylamides and their use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2852519A (en) * | 1954-12-27 | 1958-09-16 | Phillips Petroleum Co | Method for producing esters of heterocyclic nitrogen carboxylic acids |
JPS49277A (pt) * | 1972-04-18 | 1974-01-05 | ||
DE2803592A1 (de) * | 1978-01-27 | 1979-08-02 | Scott Eugene J Van | Therapeutisches mittel |
DE3174885D1 (en) * | 1981-02-03 | 1986-07-31 | Ici Plc | Process for the extraction of metal values and novel metal extractants |
DE3432094A1 (de) * | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase |
EP0198202B1 (en) * | 1985-03-09 | 1991-07-17 | Mitsubishi Corporation | Novel n-cyclohexyl-polycarboxamide compound and derivatives thereof, processes for preparing them, and use of them in preparation of host-guest complexes |
GB8702890D0 (en) * | 1987-02-10 | 1987-03-18 | Zyma Sa | Heterocyclic compounds |
ES2065355T3 (es) * | 1988-08-04 | 1995-02-16 | Hoechst Ag | Procedimiento mejorado para la preparacion de n,n'-bis (alcoxialquil)-diamidas de acidos piridina-2,4-dicarboxilicos. |
-
1987
- 1987-02-10 DE DE19873703959 patent/DE3703959A1/de not_active Withdrawn
-
1988
- 1988-02-08 ES ES88101792T patent/ES2067448T3/es not_active Expired - Lifetime
- 1988-02-08 AR AR88310031A patent/AR247732A1/es active
- 1988-02-08 AT AT88101792T patent/ATE116299T1/de not_active IP Right Cessation
- 1988-02-08 DE DE3852554T patent/DE3852554D1/de not_active Expired - Fee Related
- 1988-02-08 IL IL8536288A patent/IL85362A/en not_active IP Right Cessation
- 1988-02-08 EP EP88101792A patent/EP0278453B1/de not_active Expired - Lifetime
- 1988-02-08 FI FI880556A patent/FI91525C/fi not_active IP Right Cessation
- 1988-02-08 NZ NZ223433A patent/NZ223433A/xx unknown
- 1988-02-09 PT PT86736A patent/PT86736B/pt not_active IP Right Cessation
- 1988-02-09 NO NO880558A patent/NO174420C/no not_active IP Right Cessation
- 1988-02-09 JP JP63026723A patent/JPH0641450B2/ja not_active Expired - Lifetime
- 1988-02-09 AU AU11452/88A patent/AU599746B2/en not_active Ceased
- 1988-02-09 CA CA000558496A patent/CA1334972C/en not_active Expired - Fee Related
- 1988-02-09 ZA ZA880896A patent/ZA88896B/xx unknown
- 1988-02-09 KR KR1019880001200A patent/KR960011372B1/ko not_active IP Right Cessation
- 1988-02-09 IE IE35288A patent/IE65348B1/en not_active IP Right Cessation
- 1988-02-09 DK DK065988A patent/DK167804B1/da not_active IP Right Cessation
- 1988-02-10 HU HU88609A patent/HU205905B/hu not_active IP Right Cessation
-
1989
- 1989-11-13 US US07/434,402 patent/US5037839A/en not_active Expired - Fee Related
-
1995
- 1995-02-03 GR GR950400026T patent/GR3014958T3/el unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5519038A (en) * | 1989-07-20 | 1996-05-21 | Hoechst Aktiengesellschaft | N,N'-bis(alkoxyalkyl)-pyridine-2,4-dicarboxylic acid diamines |
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