ZA888089B - Tetrahydro-furo and-thieno/2,3-c/piridines - Google Patents

Tetrahydro-furo and-thieno/2,3-c/piridines

Info

Publication number
ZA888089B
ZA888089B ZA888089A ZA888089A ZA888089B ZA 888089 B ZA888089 B ZA 888089B ZA 888089 A ZA888089 A ZA 888089A ZA 888089 A ZA888089 A ZA 888089A ZA 888089 B ZA888089 B ZA 888089B
Authority
ZA
South Africa
Prior art keywords
piridines
furo
thieno
tetrahydro
Prior art date
Application number
ZA888089A
Other languages
English (en)
Inventor
Albrecht Harreus
Harreus Albrecht
Karl-Heinz Weber
Weber Karl-Heinz
Gerhard Walther
Walther Gerhard
Werner Stransky
Stransky Werner
Franz Josef Kuhn
Josef Kuhn Franz
Guenther Schingnitz
Schingnitz Guenther
Helmut Ensinger
Ensinger Helmut
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA888089B publication Critical patent/ZA888089B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA888089A 1987-10-29 1988-10-28 Tetrahydro-furo and-thieno/2,3-c/piridines ZA888089B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873736664 DE3736664A1 (de) 1987-10-29 1987-10-29 Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA888089B true ZA888089B (en) 1990-07-25

Family

ID=6339349

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA888089A ZA888089B (en) 1987-10-29 1988-10-28 Tetrahydro-furo and-thieno/2,3-c/piridines

Country Status (17)

Country Link
EP (1) EP0314154A3 (xx)
JP (1) JPH01157983A (xx)
KR (1) KR890006650A (xx)
AU (1) AU2443588A (xx)
CS (1) CS273193B2 (xx)
DD (1) DD283395A5 (xx)
DE (1) DE3736664A1 (xx)
DK (1) DK603588A (xx)
FI (1) FI884947A (xx)
HU (1) HU201553B (xx)
IL (1) IL88184A0 (xx)
NO (1) NO884835L (xx)
PL (1) PL275555A1 (xx)
PT (1) PT88899B (xx)
SU (1) SU1657064A3 (xx)
YU (1) YU201288A (xx)
ZA (1) ZA888089B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
US5272148A (en) * 1992-09-09 1993-12-21 Hoechst-Roussel Pharmaceuticals Incorporated Heteroarenylpiperazines
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
AU2003217747A1 (en) * 2002-02-26 2003-09-09 North Shore-Long Island Jewish Research Insitute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
EP1734941A2 (en) 2004-03-25 2006-12-27 The Feinstein Institute for Medical Research Neural tourniquet
EP1833559B1 (en) 2004-12-27 2010-11-24 The Feinstein Institute for Medical Research Treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US8391970B2 (en) 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
WO2009146030A1 (en) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
CN102215909B (zh) 2008-11-18 2014-09-10 赛博恩特医疗器械公司 优化用于消炎刺激的电极放置的装置和方法
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8788034B2 (en) 2011-05-09 2014-07-22 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
CN102573986B (zh) 2009-06-09 2016-01-20 赛博恩特医疗器械公司 用于无导线刺激器的具有袋部的神经封套
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
EP3636314B1 (en) 2009-12-23 2021-09-08 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US11406833B2 (en) 2015-02-03 2022-08-09 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
WO2017127758A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
CN114904142A (zh) 2016-01-20 2022-08-16 赛博恩特医疗器械公司 迷走神经刺激的控制
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
KR20230012585A (ko) 2020-05-21 2023-01-26 더 파인스타인 인스티튜츠 포 메디칼 리서치 미주 신경 자극을 위한 시스템들 및 방법들

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2315274A1 (fr) * 1975-06-27 1977-01-21 Parcor Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications
FR2317303A1 (fr) * 1975-07-09 1977-02-04 Parcor Procede de preparation de derives de la tetrahydrothieno (3,2-c) et (2,3-c) pyridine

Also Published As

Publication number Publication date
CS273193B2 (en) 1991-03-12
DE3736664A1 (de) 1989-05-11
HUT50824A (en) 1990-03-28
AU2443588A (en) 1989-07-13
CS712688A2 (en) 1990-06-13
IL88184A0 (en) 1989-06-30
NO884835L (no) 1989-05-02
HU201553B (en) 1990-11-28
DK603588D0 (da) 1988-10-28
FI884947A0 (fi) 1988-10-27
EP0314154A2 (de) 1989-05-03
KR890006650A (ko) 1989-06-15
JPH01157983A (ja) 1989-06-21
YU201288A (en) 1990-08-31
SU1657064A3 (ru) 1991-06-15
DK603588A (da) 1989-04-30
PT88899B (pt) 1993-01-29
NO884835D0 (no) 1988-10-28
DD283395A5 (de) 1990-10-10
FI884947A (fi) 1989-04-30
EP0314154A3 (de) 1990-12-05
PL275555A1 (en) 1989-05-02

Similar Documents

Publication Publication Date Title
ZA888089B (en) Tetrahydro-furo and-thieno/2,3-c/piridines
GR3001763T3 (en) Cycloalkano(1,2-b)indole-sulfonamides
ZA884603B (en) 2,5-dihydropyrroles
ZA889710B (en) 4-aralkyl-5-substituted-1,2,4-triazole-5-thiols
KR970009590B1 (en) 1.2.3.4.-tetrahydro -5-nitropyrimidine derivatives
EP0316843A3 (en) 1,2,3,4-tetrahydro-5-nitropyrimidine derivatives
EP0217214B1 (en) 2,4-dioxopyrrolo(2,3-c)pyrroles
IL83679A0 (en) 2,4,6-trihydroxy-s-triazine derivatives
ZA889251B (en) 8,9-annelated-beta-carbolines and 8,9-annelated-3,4-dihydro-beta-carbolines
GR3000539T3 (en) 3,4-dihydro-2h-pyrans
JPS6450861A (en) 3,5-dialkyl-1-arylpyrazoles
CS569987A1 (en) Zpusob vyroby 2 naftylamin 6,8 disulfonove kyseliny
JPS6434951A (en) Vermicide based on 2,3-diaminomaleonitrile derivative
CS22787A1 (en) Zpusob pripravy 2,6-dialkoxybenzonitrilu
ZA871249B (en) Cycloalkano(1,2-b)-indole-sulphonamides
IE871771L (en) 1,4-piperazines
IE872988L (en) 2,6-diamino-3-halobenzylpyridines
IE871970L (en) 2,7-methanobenzoxazonines
CS770787A1 (en) Sposob pripravy 2,2 dibenzotiazolyldisulfidu
CS689087A1 (en) Zpusob vyroby 2,5 dichloranilin 4 sulfonove kyseliny
CS569887A1 (en) Zpusob izolace 2 naftol 6,8 disulfonove kyseliny
CS161787A1 (en) N oxidy 2,2,5 trimetyl 3 alkyloxazolidinov
GB8712993D0 (en) 1,2-alkylidene-3-phosphoryl-glycerol derivatives
ZA884493B (en) 2,2-dimethylchroman-3-o 1 derivatives
CS438087A1 (en) Zpusob pripravy 2 methyl 7,8 oktadecinu