ZA886336B - Novel benzimidazole derivatives - Google Patents

Novel benzimidazole derivatives

Info

Publication number
ZA886336B
ZA886336B ZA886336A ZA886336A ZA886336B ZA 886336 B ZA886336 B ZA 886336B ZA 886336 A ZA886336 A ZA 886336A ZA 886336 A ZA886336 A ZA 886336A ZA 886336 B ZA886336 B ZA 886336B
Authority
ZA
South Africa
Prior art keywords
benzimidazole derivatives
novel benzimidazole
novel
addn
substd
Prior art date
Application number
ZA886336A
Other languages
English (en)
Inventor
Klaus Schoellkopf
Schoellkopf Klaus
Helmut Wachtel
Wachtel Helmut
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA886336B publication Critical patent/ZA886336B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
ZA886336A 1987-08-25 1988-08-25 Novel benzimidazole derivatives ZA886336B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873728695 DE3728695A1 (de) 1987-08-25 1987-08-25 Neue benzimidazol-derivate

Publications (1)

Publication Number Publication Date
ZA886336B true ZA886336B (en) 1989-04-26

Family

ID=6334659

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886336A ZA886336B (en) 1987-08-25 1988-08-25 Novel benzimidazole derivatives

Country Status (17)

Country Link
US (1) US4925854A (no)
EP (1) EP0304789B1 (no)
JP (1) JP2818170B2 (no)
AT (1) ATE86982T1 (no)
AU (1) AU615939B2 (no)
CA (1) CA1330440C (no)
DD (1) DD274215A5 (no)
DE (2) DE3728695A1 (no)
DK (1) DK169701B1 (no)
ES (1) ES2054752T3 (no)
FI (1) FI99013C (no)
HU (1) HU201746B (no)
IE (1) IE63283B1 (no)
IL (1) IL87561A (no)
NO (1) NO170852C (no)
PT (1) PT88326B (no)
ZA (1) ZA886336B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
US5371102A (en) * 1992-03-11 1994-12-06 University Of Hawaii Compositions and methods of inhibiting thyroid activity
IL113472A0 (en) 1994-04-29 1995-07-31 Lilly Co Eli Non-peptidyl tachykinin receptor antogonists
US5565454A (en) * 1995-05-31 1996-10-15 Ergo Science, Incorporated Method for preventing intervention-associated stenosis and other symptoms associated with stenosis of blood vessels following non-bypass, invasive interventions
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) * 1995-12-23 1996-02-28 Astra Pharma Prod Pharmaceutically active compounds
WO2004032861A2 (en) * 2002-10-11 2004-04-22 Bristol-Myers Squibb Company Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
SG11201402551YA (en) 2011-12-16 2014-08-28 Colgate Palmolive Co Color changing compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3813409A (en) * 1972-07-31 1974-05-28 Squibb & Sons Inc Benzimidazolinone compounds
DE3042481A1 (de) * 1980-11-11 1982-06-16 A. Nattermann & Cie GmbH, 5000 Köln (omega)-(2-oxo-benzazolinyl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4367337A (en) * 1981-01-05 1983-01-04 The Sherwin-Williams Company Process for conversion of benzimidazolones to benzotriazoles
DE3586123D1 (de) * 1984-08-15 1992-07-02 Schering Ag Neue dopamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
US4554287A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones

Also Published As

Publication number Publication date
FI883930A0 (fi) 1988-08-25
AU2149888A (en) 1989-03-02
NO170852B (no) 1992-09-07
JP2818170B2 (ja) 1998-10-30
DK474288A (da) 1989-02-26
IE882552L (en) 1989-02-25
IL87561A0 (en) 1989-01-31
US4925854A (en) 1990-05-15
HUT49589A (en) 1989-10-30
PT88326B (pt) 1995-03-31
NO170852C (no) 1992-12-16
IE63283B1 (en) 1995-04-05
NO883776D0 (no) 1988-08-24
DD274215A5 (de) 1989-12-13
ATE86982T1 (de) 1993-04-15
DE3879322D1 (de) 1993-04-22
FI99013C (fi) 1997-09-25
EP0304789A3 (en) 1989-10-04
DK474288D0 (da) 1988-08-25
CA1330440C (en) 1994-06-28
FI883930A (fi) 1989-02-26
DK169701B1 (da) 1995-01-16
EP0304789A2 (de) 1989-03-01
HU201746B (en) 1990-12-28
JPS6468359A (en) 1989-03-14
AU615939B2 (en) 1991-10-17
NO883776L (no) 1989-02-27
FI99013B (fi) 1997-06-13
ES2054752T3 (es) 1994-08-16
PT88326A (pt) 1989-06-30
DE3728695A1 (de) 1989-03-09
IL87561A (en) 1993-02-21
EP0304789B1 (de) 1993-03-17

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