ZA884272B - Leukotriene antagonists - Google Patents

Leukotriene antagonists

Info

Publication number
ZA884272B
ZA884272B ZA884272A ZA884272A ZA884272B ZA 884272 B ZA884272 B ZA 884272B ZA 884272 A ZA884272 A ZA 884272A ZA 884272 A ZA884272 A ZA 884272A ZA 884272 B ZA884272 B ZA 884272B
Authority
ZA
South Africa
Prior art keywords
alkyl
alkoxy
leukotriene antagonists
cor3
optionally substituted
Prior art date
Application number
ZA884272A
Other languages
English (en)
Inventor
James Simpson Frazee
Simpson Frazee James
John Gerald Gleason
Gerald Gleason John
Ralph Floyd Hall
Floyd Hall Ralph
Original Assignee
Shmithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shmithkline Beckman Corp filed Critical Shmithkline Beckman Corp
Publication of ZA884272B publication Critical patent/ZA884272B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
ZA884272A 1987-06-24 1988-06-15 Leukotriene antagonists ZA884272B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6658887A 1987-06-24 1987-06-24

Publications (1)

Publication Number Publication Date
ZA884272B true ZA884272B (en) 1989-06-28

Family

ID=22070455

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA884272A ZA884272B (en) 1987-06-24 1988-06-15 Leukotriene antagonists

Country Status (14)

Country Link
EP (1) EP0296732B1 (hu)
JP (1) JPS6434955A (hu)
CN (1) CN1030074A (hu)
AT (1) ATE68176T1 (hu)
AU (1) AU620037B2 (hu)
CA (1) CA1334200C (hu)
DE (1) DE3865373D1 (hu)
DK (1) DK327088A (hu)
FI (1) FI882866A (hu)
HU (1) HU201521B (hu)
NO (1) NO882607L (hu)
NZ (1) NZ225021A (hu)
PT (1) PT87615B (hu)
ZA (1) ZA884272B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4937253A (en) * 1985-04-19 1990-06-26 Smithkline Beecham Corporation Ester prodrugs
US4954513A (en) * 1988-12-23 1990-09-04 Smithkline Beecham Corporation Leukotriene antagonists
DE3905518A1 (de) * 1989-02-23 1990-10-11 Bayer Ag Substituierte phenoxyphenylpropionsaeure-derivate
CA2018437A1 (en) * 1989-06-14 1990-12-14 James Simpson Frazee Leukotriene antagonists
ATE96149T1 (de) * 1989-07-27 1993-11-15 Bayer Ag Arylalkensaeurederivate als leukotrienantagonisten.
US5266713A (en) * 1989-07-27 1993-11-30 Miles Inc. Aryl alkenoic acid derivatives as leukotriene antagonists
WO1991018889A1 (en) * 1990-06-06 1991-12-12 Smithkline Beecham Corporation Leukotriene antagonists
EP0541706B1 (en) * 1990-08-01 1995-09-13 Smithkline Beecham Corporation Process and intermediate for the preparation of 2-hydroxy-3-sulfido-3-phenyl propanoic acids
DE19943634A1 (de) 1999-09-13 2001-04-12 Bayer Ag Neuartige Dicarbonsäurederivate mit pharmazeutischen Eigenschaften

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874792A (en) * 1985-04-19 1989-10-17 Smithkline Beckman Corporation Thiophenyl Alkanoic acids useful as leukotriene antagonists
ATE90330T1 (de) * 1985-04-19 1993-06-15 Smithkline Beecham Corp Zwischenprodukte fuer die herstellung von leukotrien-antagonisten.

Also Published As

Publication number Publication date
NZ225021A (en) 1991-02-26
CN1030074A (zh) 1989-01-04
PT87615B (pt) 1992-09-30
DE3865373D1 (de) 1991-11-14
AU620037B2 (en) 1992-02-13
JPS6434955A (en) 1989-02-06
AU1759588A (en) 1989-01-05
PT87615A (pt) 1988-06-01
NO882607D0 (no) 1988-06-14
EP0296732A1 (en) 1988-12-28
FI882866A (fi) 1988-12-25
ATE68176T1 (de) 1991-10-15
FI882866A0 (fi) 1988-06-15
HU201521B (en) 1990-11-28
DK327088A (da) 1988-12-25
EP0296732B1 (en) 1991-10-09
DK327088D0 (da) 1988-06-15
NO882607L (no) 1988-12-27
CA1334200C (en) 1995-01-31
HUT47242A (en) 1989-02-28

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