ZA882526B - Benzazepine derivatives - Google Patents

Benzazepine derivatives

Info

Publication number
ZA882526B
ZA882526B ZA882526A ZA882526A ZA882526B ZA 882526 B ZA882526 B ZA 882526B ZA 882526 A ZA882526 A ZA 882526A ZA 882526 A ZA882526 A ZA 882526A ZA 882526 B ZA882526 B ZA 882526B
Authority
ZA
South Africa
Prior art keywords
benzazepine derivatives
benzazepine
derivatives
Prior art date
Application number
ZA882526A
Other languages
English (en)
Inventor
David Mack Floyd
Mack Floyd David
John Krapcho
Krapcho John
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ZA882526B publication Critical patent/ZA882526B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA882526A 1987-04-24 1988-04-11 Benzazepine derivatives ZA882526B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/042,187 US4748239A (en) 1985-06-12 1987-04-24 Benzazepine derivatives

Publications (1)

Publication Number Publication Date
ZA882526B true ZA882526B (en) 1988-11-30

Family

ID=21920521

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA882526A ZA882526B (en) 1987-04-24 1988-04-11 Benzazepine derivatives

Country Status (17)

Country Link
US (1) US4748239A (da)
EP (1) EP0289241A1 (da)
JP (1) JPS63280070A (da)
KR (1) KR890016015A (da)
CN (1) CN88102422A (da)
AU (1) AU603654B2 (da)
CA (1) CA1302409C (da)
DD (1) DD268688A5 (da)
DK (1) DK223588A (da)
FI (1) FI881902A (da)
HU (1) HU199125B (da)
IL (1) IL86081A0 (da)
NO (1) NO881762L (da)
NZ (1) NZ224165A (da)
PT (1) PT87309B (da)
YU (1) YU81588A (da)
ZA (1) ZA882526B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774239A (en) * 1987-08-26 1988-09-27 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4871731A (en) * 1987-10-07 1989-10-03 Marion Laboratories, Inc. Captopril and diltiazem composition and the like
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
IL90189A0 (en) * 1988-06-01 1989-12-15 Squibb & Sons Inc Pharmaceutical compositions containing a benzazepine-type calcium channel blocker
DE3990664T1 (de) * 1988-06-20 1991-04-25 Squibb & Sons Inc Benzazepin- und benzothiazepin-derivate
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US4965356A (en) * 1988-11-23 1990-10-23 E. R. Squibb & Sons, Inc. Resolution process for benzazepine intermediates
US4885364A (en) * 1988-11-23 1989-12-05 E. R. Squibb & Sons, Inc. Resolution process for benzazepine intermediates
US4952692A (en) * 1989-04-04 1990-08-28 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4946840A (en) * 1989-04-06 1990-08-07 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US5559017A (en) * 1989-08-09 1996-09-24 E. R. Squibb & Sons, Inc. Microbial reduction of benzazepines and benzothiazepine derivatives
US6277844B1 (en) 1998-09-14 2001-08-21 Sydney Spector Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
CN102942558B (zh) * 2012-05-18 2014-04-16 天津药物研究院 一种苯并氮杂卓衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) * 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3312691A (en) * 1963-08-23 1967-04-04 Ciba Geigy Corp 2, 3, 4, 5-tetrahydro-1-benzazepin-2-ones
US3330823A (en) * 1964-12-16 1967-07-11 Squibb & Sons Inc N-amino-loweralkylene-benzo-lactams
US3395150A (en) * 1965-02-26 1968-07-30 Squibb & Sons Inc Benzothiazepine carboxamides and derivatives thereof
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
CA1271747C (en) * 1985-06-12 1990-07-17 BENZAZEPINE DERIVATIVES

Also Published As

Publication number Publication date
EP0289241A1 (en) 1988-11-02
DK223588D0 (da) 1988-04-22
FI881902A (fi) 1988-10-25
JPS63280070A (ja) 1988-11-17
NO881762L (no) 1988-10-25
NO881762D0 (no) 1988-04-22
IL86081A0 (en) 1988-09-30
HU199125B (en) 1990-01-29
YU81588A (en) 1990-04-30
KR890016015A (ko) 1989-11-28
CA1302409C (en) 1992-06-02
AU603654B2 (en) 1990-11-22
US4748239A (en) 1988-05-31
PT87309A (pt) 1988-05-01
AU1455288A (en) 1988-10-27
NZ224165A (en) 1990-04-26
HUT47252A (en) 1989-02-28
FI881902A0 (fi) 1988-04-22
CN88102422A (zh) 1988-12-07
PT87309B (pt) 1992-08-31
DK223588A (da) 1988-10-25
DD268688A5 (de) 1989-06-07

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