ZA881953B - Concentrated stable fluorochemical aqueous emulsions - Google Patents

Concentrated stable fluorochemical aqueous emulsions

Info

Publication number
ZA881953B
ZA881953B ZA881953A ZA881953A ZA881953B ZA 881953 B ZA881953 B ZA 881953B ZA 881953 A ZA881953 A ZA 881953A ZA 881953 A ZA881953 A ZA 881953A ZA 881953 B ZA881953 B ZA 881953B
Authority
ZA
South Africa
Prior art keywords
aqueous emulsions
concentrated stable
stable fluorochemical
fluorochemical aqueous
concentrated
Prior art date
Application number
ZA881953A
Other languages
English (en)
Inventor
Frank Kenneth Schweighardt
Kenneth Schweighardt Frank
Charles Randall Kayhart
Randall Kayhart Charles
Original Assignee
Air Prod & Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Air Prod & Chem filed Critical Air Prod & Chem
Publication of ZA881953B publication Critical patent/ZA881953B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Colloid Chemistry (AREA)
ZA881953A 1987-03-20 1988-03-18 Concentrated stable fluorochemical aqueous emulsions ZA881953B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/028,521 US4895876A (en) 1987-03-20 1987-03-20 Concentrated stable fluorochemical aqueous emulsions containing triglycerides

Publications (1)

Publication Number Publication Date
ZA881953B true ZA881953B (en) 1989-11-29

Family

ID=21843917

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881953A ZA881953B (en) 1987-03-20 1988-03-18 Concentrated stable fluorochemical aqueous emulsions

Country Status (10)

Country Link
US (1) US4895876A (de)
EP (1) EP0282949B1 (de)
JP (1) JPS63264521A (de)
KR (1) KR900006830B1 (de)
BR (1) BR8801157A (de)
CA (1) CA1312011C (de)
DE (1) DE3871195D1 (de)
ES (1) ES2032887T3 (de)
MX (1) MX169411B (de)
ZA (1) ZA881953B (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US4781676A (en) * 1987-02-20 1988-11-01 Air Products And Chemicals, Inc. Interstitial administration of perfluorochemical emulsions for reoxygenation of hypoxic tumor cells
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
JPH0372423A (ja) * 1989-05-26 1991-03-27 Green Cross Corp:The パーフルオロカーボン化合物含有乳化製剤
EP0440925A1 (de) * 1989-12-13 1991-08-14 The Green Cross Corporation Aufbewahrungsflüssigkeit und Aufbewahrungsverfahren für innere Organe
US20020150539A1 (en) * 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
CA2050212C (en) * 1990-09-03 1997-09-30 Andrew M. Murray Hair treatment composition
US5205290A (en) 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US5146014A (en) * 1991-07-02 1992-09-08 Air Products And Chemicals, Inc. Perfluoroethyldimethyl cyclohexane
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
WO1993002653A1 (en) * 1991-08-08 1993-02-18 Segel Leigh D Fluorocarbon blood substitute
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
EP0605477B2 (de) * 1991-09-17 2007-06-20 GE Healthcare AS Gasförmige ultraschallkontrastmittel
US5304325A (en) * 1991-11-13 1994-04-19 Hemagen/Pfc Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
AU667847B2 (en) * 1991-11-14 1996-04-18 Alliance Pharmaceutical Corporation Method and apparatus for partial liquid ventilation using fluorocarbons
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
GB9204509D0 (en) * 1992-03-02 1992-04-15 Unilever Plc Hair care composition
US5628930A (en) * 1992-10-27 1997-05-13 Alliance Pharmaceutical Corp. Stabilization of fluorocarbon emulsions
US5595687A (en) 1992-10-30 1997-01-21 Thomas Jefferson University Emulsion stability
US5420359A (en) * 1992-12-11 1995-05-30 Minnesota Mining And Manufacturing Company Chlorofluoroether compositions and preparation thereof
CA2154590C (en) * 1993-01-25 2001-06-12 Steven C. Quay Phase shift colloids as ultrasound contrast agents
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
US5635538A (en) * 1993-03-16 1997-06-03 Alliance Pharmaceutical Corp. Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
US5969004A (en) * 1993-10-15 1999-10-19 The Gillette Company Aqueous inks
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US6521211B1 (en) * 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US5726209A (en) * 1995-06-07 1998-03-10 Alliance Pharmaceutical Corp. Liquid fluorocarbon emulsion as a vascular nitric oxide reservoir
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
US5837221A (en) * 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US20050019266A1 (en) * 1997-05-06 2005-01-27 Unger Evan C. Novel targeted compositions for diagnostic and therapeutic use
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
ES2305368T3 (es) * 2002-05-10 2008-11-01 THE PROCTER & GAMBLE COMPANY Tisu estampado en relieve que tiene fibras superficiales sueltas y metodo para su produccion.
GB0319500D0 (en) * 2003-08-19 2003-09-17 Resolution Chemicals Ltd Particle-size reduction apparatus,and use thereof
US8012457B2 (en) * 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
WO2007059431A1 (en) 2005-11-14 2007-05-24 The Trustees Of Columbia University In The City Of New York Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs
WO2014160989A2 (en) * 2013-03-28 2014-10-02 The Trustees Of Columbia University In The City Of New York Reperfusion with omega-3 glycerides promotes donor organ protection for transplantation
CN101443272A (zh) * 2006-05-15 2009-05-27 弗吉尼亚联邦大学 用于受控和持续产生并输送过氧化物的方法和组合物
US8410181B2 (en) 2006-09-19 2013-04-02 The Trustees Of Columbia University In The City Of New York Omega-3 diglyceride emulsions
US8618056B2 (en) 2007-12-22 2013-12-31 Cuthbert O. Simpkins Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
WO2010008594A1 (en) * 2008-07-18 2010-01-21 Oxygen Biotherapeutics, Inc. Method of treating traumatic brain injury
US20100144597A1 (en) * 2008-12-10 2010-06-10 Ward Kevin R Novel combinatorial approaches to enhancing oxygen transport to tissues
CA2756685C (en) * 2009-04-15 2019-12-24 Oxygen Biotherapeutics, Inc. Emulsions of perfluorocarbons
MX2012010769A (es) * 2010-03-19 2013-02-27 Oxygen Biotherapeutics Inc Formulaciones perfluorocarbonadas oftalmicas en forma de crema.
CN103491976B (zh) * 2011-01-14 2015-04-01 卡思伯特·O·辛普金斯 用于处理与缺乏血液供给、休克和神经损伤相关的疾病的方法和组合物
US20120196270A1 (en) * 2011-02-02 2012-08-02 Sangart, Inc. Methods for preserving an organ for transplantation using a hemoglobin-carbon monoxide complex
WO2024046999A1 (de) 2022-08-31 2024-03-07 Johann Wolfgang Goethe-Universität Frankfurt am Main Lecithin-modifizierte nanoskalierte sauerstoffträger (lenox)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5331209B2 (de) * 1973-10-05 1978-09-01
US4105798A (en) * 1976-07-19 1978-08-08 Sun Ventures, Inc. Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
JPS5331208A (en) * 1976-09-02 1978-03-24 Matsushita Electric Ind Co Ltd Lubricator for closed compressor and the like
JPS5924132B2 (ja) * 1980-12-02 1984-06-07 株式会社 林原生物化学研究所 栄養補給用乳剤の製法
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
US4443480A (en) * 1982-04-12 1984-04-17 Children's Hospital Medical Center Artificial blood and other gas transport agents
US4497829A (en) * 1982-07-27 1985-02-05 The University Of Pennsylvania Process for preparing perfluorochemical emulsion artificial blood
US4397870A (en) * 1982-07-27 1983-08-09 The University Of Pennsylvania Process for prolonging retention of emulsion particles in the bloodstream
US4423077A (en) * 1982-07-27 1983-12-27 The University Of Pennsylvania Perfluorochemical emulsion artificial blood
JPS6033367A (ja) * 1983-08-04 1985-02-20 Nec Corp アルミニウムのドライエッチング方法
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
SE8505048L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Nutritionsemulsion med syretransporterande egenskaper
ES2054658T3 (es) * 1986-01-24 1994-08-16 Childrens Hosp Medical Center Metodo para la preparacion de una emulsion fisiologicamente aceptable.
US4781676A (en) * 1987-02-20 1988-11-01 Air Products And Chemicals, Inc. Interstitial administration of perfluorochemical emulsions for reoxygenation of hypoxic tumor cells
US4866096A (en) * 1987-03-20 1989-09-12 Air Products And Chemicals, Inc. Stable fluorochemical aqueous emulsions

Also Published As

Publication number Publication date
EP0282949B1 (de) 1992-05-20
EP0282949A3 (en) 1989-08-09
MX169411B (es) 1993-07-02
KR900006830B1 (ko) 1990-09-22
EP0282949A2 (de) 1988-09-21
KR880010755A (ko) 1988-10-24
CA1312011C (en) 1992-12-29
DE3871195D1 (de) 1992-06-25
BR8801157A (pt) 1988-10-18
US4895876A (en) 1990-01-23
ES2032887T3 (es) 1993-03-01
JPS63264521A (ja) 1988-11-01

Similar Documents

Publication Publication Date Title
ZA881953B (en) Concentrated stable fluorochemical aqueous emulsions
EP0282948A3 (en) Stable fluorocarbon aqueous emulsions
GB2209759B (en) Aqueous dispersions
GB2209758B (en) Aqueous dispersions
GB8821515D0 (en) Aqueous dispersions
GB8721536D0 (en) Aqueous dispersions
GB8725378D0 (en) Aqueous suspensions
NZ226927A (en) Stable aqueous microemulsion cleaners
EP0302701A3 (en) Microbicidal microemulsion
JPS6454051A (en) Polyacrylonitrile emulsion
IL83380A0 (en) Stable aqueous cisplatin solutions
GR3002388T3 (en) Stable aqueous suspension concentrate composition
GB8721537D0 (en) Aqueous dispersions
GB8711275D0 (en) Aqueous solution
JPS6460688A (en) Aqueous arylfluorophosphite suspension
GB8417811D0 (en) Aqueous solution
PL262649A1 (en) Aqueous emulsion based pesticide
GB2149665B (en) Stabilized aqueous pesticidal suspension concentrate
JPS6443511A (en) Aqueous synthetic dispersion
GB8503253D0 (en) Aqueous formulations
GB8614482D0 (en) Body member
GB8812332D0 (en) Aqueous halogenite compositions
GB8715851D0 (en) Reference point
GB8721535D0 (en) Aqueous dispersions
GB8721534D0 (en) Aqueous dispersions