ZA881383B - 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid derivatives,processes for preparing them and the pharmaceutical compositions which contain them - Google Patents

2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid derivatives,processes for preparing them and the pharmaceutical compositions which contain them

Info

Publication number
ZA881383B
ZA881383B ZA881383A ZA881383A ZA881383B ZA 881383 B ZA881383 B ZA 881383B ZA 881383 A ZA881383 A ZA 881383A ZA 881383 A ZA881383 A ZA 881383A ZA 881383 B ZA881383 B ZA 881383B
Authority
ZA
South Africa
Prior art keywords
radical
carbon atoms
denotes
linear
optionally substituted
Prior art date
Application number
ZA881383A
Other languages
English (en)
Inventor
Gilbert Lavielle
Lavielle Gilbert
Jean Lepagnol
Lepagnol Jean
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of ZA881383B publication Critical patent/ZA881383B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA881383A 1987-02-27 1988-02-26 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid derivatives,processes for preparing them and the pharmaceutical compositions which contain them ZA881383B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8702630A FR2611713B1 (fr) 1987-02-27 1987-02-27 Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA881383B true ZA881383B (en) 1988-12-28

Family

ID=9348401

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA881383A ZA881383B (en) 1987-02-27 1988-02-26 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid derivatives,processes for preparing them and the pharmaceutical compositions which contain them

Country Status (16)

Country Link
US (2) US4859700A (da)
EP (1) EP0282390B1 (da)
JP (1) JPS63227582A (da)
AT (1) ATE63309T1 (da)
AU (1) AU598345B2 (da)
CA (1) CA1313871C (da)
DE (1) DE3862660D1 (da)
DK (1) DK167063B1 (da)
ES (1) ES2009553A6 (da)
FR (1) FR2611713B1 (da)
GR (1) GR1000125B (da)
IE (1) IE60500B1 (da)
NZ (1) NZ223663A (da)
OA (1) OA08813A (da)
PT (1) PT86851B (da)
ZA (1) ZA881383B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0370560B1 (en) * 1988-11-24 1994-01-12 Akzo Nobel N.V. Pharmaceutical composition containing 1-[mono- or bis (trifluoromethyl)-2-pyridinyl] piperazines
GB9205049D0 (en) * 1992-03-09 1992-04-22 Ici Plc Polycyclic dyes
US6207665B1 (en) 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
EP1303502A2 (en) * 2000-07-06 2003-04-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Tetrahydrobenzothiazole analogues as neuroprotective agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2513698A (en) * 1945-03-09 1950-07-04 Abbott Lab 2 (3) benxofuranone derivatives and methods of making them
GB1173312A (en) * 1966-03-17 1969-12-10 Kefalas As Heterocyclic Compounds
GB2044272B (en) * 1979-02-05 1983-03-16 Sandoz Ltd Stabilising polymers
US4514415A (en) * 1981-10-28 1985-04-30 Ciba Geigy Corporation Benzofuran-2(3H)-ones used as anti-inflammatory agents
US4663347A (en) * 1983-10-31 1987-05-05 Merck Frosst Canada, Inc. Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
GB8426424D0 (en) * 1984-10-19 1984-11-28 Biorex Laboratories Ltd Chalcone derivatives
FR2593504B1 (fr) * 1986-01-30 1988-12-09 Ile De France Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques

Also Published As

Publication number Publication date
GR1000125B (el) 1991-07-31
FR2611713B1 (fr) 1990-11-30
EP0282390A1 (fr) 1988-09-14
NZ223663A (en) 1990-01-29
FR2611713A1 (fr) 1988-09-09
EP0282390B1 (fr) 1991-05-08
IE60500B1 (en) 1994-07-27
US4885299A (en) 1989-12-05
DK104388A (da) 1988-08-28
ES2009553A6 (es) 1989-10-01
OA08813A (fr) 1989-03-31
JPH0558633B2 (da) 1993-08-27
JPS63227582A (ja) 1988-09-21
DK104388D0 (da) 1988-02-26
AU1234488A (en) 1988-09-01
ATE63309T1 (de) 1991-05-15
GR880100111A (en) 1988-12-16
DK167063B1 (da) 1993-08-23
US4859700A (en) 1989-08-22
AU598345B2 (en) 1990-06-21
PT86851B (pt) 1992-05-29
PT86851A (pt) 1988-03-01
CA1313871C (fr) 1993-02-23
DE3862660D1 (de) 1991-06-13
IE880528L (en) 1988-08-27

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