ZA877171B - A substance or composition comprising 3'-deoxythymidin-2'-ene(3'-deoxy-2',3'-didehydrothymidine)for use in treating patients infected with retroviruses - Google Patents

A substance or composition comprising 3'-deoxythymidin-2'-ene(3'-deoxy-2',3'-didehydrothymidine)for use in treating patients infected with retroviruses

Info

Publication number
ZA877171B
ZA877171B ZA877171A ZA877171A ZA877171B ZA 877171 B ZA877171 B ZA 877171B ZA 877171 A ZA877171 A ZA 877171A ZA 877171 A ZA877171 A ZA 877171A ZA 877171 B ZA877171 B ZA 877171B
Authority
ZA
South Africa
Prior art keywords
deoxythymidin
didehydrothymidine
deoxy
ene
retroviruses
Prior art date
Application number
ZA877171A
Other languages
English (en)
Inventor
Lin Tai-Shun
H. Prusoff William
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25478432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA877171(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yale University filed Critical Yale University
Publication of ZA877171B publication Critical patent/ZA877171B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA877171A 1986-12-17 1987-09-23 A substance or composition comprising 3'-deoxythymidin-2'-ene(3'-deoxy-2',3'-didehydrothymidine)for use in treating patients infected with retroviruses ZA877171B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/942,666 US4978655A (en) 1986-12-17 1986-12-17 Use of 3'-deoxythymidin-2'-ene (3'deoxy-2',3'-didehydrothymidine) in treating patients infected with retroviruses

Publications (1)

Publication Number Publication Date
ZA877171B true ZA877171B (en) 1988-03-24

Family

ID=25478432

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA877171A ZA877171B (en) 1986-12-17 1987-09-23 A substance or composition comprising 3'-deoxythymidin-2'-ene(3'-deoxy-2',3'-didehydrothymidine)for use in treating patients infected with retroviruses

Country Status (22)

Country Link
US (1) US4978655A (fi)
EP (1) EP0273277B1 (fi)
JP (1) JPH07116041B2 (fi)
KR (1) KR960000433B1 (fi)
AT (1) ATE77554T1 (fi)
AU (1) AU593405B2 (fi)
CA (1) CA1293447C (fi)
DE (1) DE3780016T2 (fi)
DK (1) DK174627B1 (fi)
EG (1) EG19157A (fi)
ES (1) ES2038650T3 (fi)
FI (1) FI875544A (fi)
GR (1) GR3005691T3 (fi)
HK (1) HK55896A (fi)
IE (1) IE60866B1 (fi)
IL (1) IL84790A (fi)
LU (1) LU88822I2 (fi)
NL (1) NL960024I2 (fi)
NZ (1) NZ222935A (fi)
PH (1) PH26380A (fi)
PT (1) PT86346B (fi)
ZA (1) ZA877171B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631370A (en) 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
US5175292A (en) * 1988-01-20 1992-12-29 Regents Of The University Of Minnesota Intermediates for the preparation of dideoxycarbocyclic nucleosides
US6207650B1 (en) 1989-05-15 2001-03-27 Bristol-Myers Squibb Company Antiviral, highly water soluble, stable, crystalline salts of 2′, 3′-dideoxyinosine, 2′, 3′-dideoxy-2′, 3′-didehydrothymidine and 2′, 3′-dideoxy-2′-fluoroinosine
FI95269C (fi) * 1989-05-15 1996-01-10 Squibb Bristol Myers Co 2',3'-dideoksi-inosiinimonohydraatin, 2',3'-dideoksi-2',3'-didehydrot ymidiinimonohydraatin ja 2',3'-dideoksi-2'-fluori-inosiinihemihydraatin antiviraalisia, hyvin vesiliukoisia, stabiileja, kiteisiä suoloja
US5608048A (en) * 1995-06-05 1997-03-04 Bristol-Myers Squibb Company d4 T polymorphic Form 1 process
US5840711A (en) * 1995-06-21 1998-11-24 University Of Kentucky Research Foundation Compositions containing lithium inorganic salts and anti-viral drugs and method of treating viral infections such as acquired immunodeficiency syndrome
CA2189097A1 (en) 1995-11-15 1997-05-16 Pin-Fang Lin Composition and method of treating retroviral infection
US5719132A (en) * 1996-06-27 1998-02-17 Bristol-Myers Squibb Company Compositions and methods of treating HIV with d4T, 5-fluorouracil/tegafur, and uracil
WO2000016625A1 (en) * 1998-09-23 2000-03-30 University Of Kentucky Research Foundation Antiviral drug compositions containing lithium inorganic salts
KR20030011805A (ko) 2000-03-30 2003-02-11 브리스톨-마이어스스퀴브컴파니 스타부딘을 함유하는 서방성 비들렛
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
CA2514466C (en) * 2003-02-19 2015-05-26 Yale University Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections
US20040200730A1 (en) * 2003-04-14 2004-10-14 Kyo Jibiki Hydrometallurgical copper recovery process
EP2258376B1 (en) 2004-07-27 2019-02-27 Gilead Sciences, Inc. Phosphonate analogs of HIV inhibitor compounds
BRPI0617074A2 (pt) * 2005-08-31 2011-07-12 Cipla Ltd composição farmacêutica, uso de lamivudina, nevirapina e stavudina, uso de stavudina, lamivudina e nevirapina, método para tratar uma infecção viral em um humano, método para preparar uma composição farmacêutica, método para preparar uma forma de dosagem unitária farmacêutica bicamadas e método para preparar uma forma de dosagem unitária farmacêutica tri-camadas
KR101687841B1 (ko) 2008-12-09 2016-12-19 길리애드 사이언시즈, 인코포레이티드 톨-유사 수용체의 조절제
US20110223131A1 (en) 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
WO2016001907A1 (en) 2014-07-02 2016-01-07 Prendergast Patrick T Mogroside iv and mogroside v as agonist/stimulator/un-blocking agent for toll-like receptor 4 and adjuvant for use in human/animal vaccine and to stimulate immunity against disease agents.
CA2954056C (en) 2014-07-11 2020-04-28 Gilead Sciences, Inc. Modulators of toll-like receptors for the treatment of hiv
JP2018527366A (ja) 2015-09-15 2018-09-20 ギリアード サイエンシーズ, インコーポレイテッド HIVを処置するためのtoll様レセプターのモジュレーター

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322747A (en) * 1965-04-01 1967-05-30 Merck & Co Inc Thionocarbonate nucleosides
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
JPS5943550B2 (ja) * 1975-08-29 1984-10-23 田辺製薬株式会社 不飽和ヌクレオシドの製法
DE3515870A1 (de) * 1985-05-03 1986-11-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 5-fluortoluol-2,4-disulfochlorid
US4710492A (en) * 1986-06-23 1987-12-01 Yale University 3'-azido-2',3'-dideoxy-5-halouridine and its use in treating patients infected with retroviruses
NL8700089A (nl) * 1987-01-15 1988-08-01 Stichting Rega V Z W Therapeutische toepassing van dideoxythymidine en dideoxythymidineen.
DE3806633A1 (de) * 1987-09-01 1989-03-09 Bayer Ag Antivirales mittel
JP2648329B2 (ja) * 1987-09-18 1997-08-27 エフ・ホフマン−ラ ロシュ アーゲー エイズの予防または治療用医薬組成物
SE8704298D0 (sv) * 1987-11-03 1987-11-03 Astra Ab Compounds for use in therapy
JPH0227782A (ja) * 1988-07-15 1990-01-30 Hikari Gijutsu Kenkyu Kaihatsu Kk 半導体発光素子
JPH0438727A (ja) * 1990-06-04 1992-02-07 Sharp Corp 光学式ピックアップ装置の対物レンズ塵埃付着防止機構

Also Published As

Publication number Publication date
PT86346A (en) 1988-01-01
IE60866B1 (en) 1994-08-24
KR960000433B1 (ko) 1996-01-06
NL960024I2 (nl) 1997-06-02
JPH07116041B2 (ja) 1995-12-13
EP0273277B1 (en) 1992-06-24
FI875544A (fi) 1988-06-18
DK557087D0 (da) 1987-10-23
FI875544A0 (fi) 1987-12-16
EP0273277A2 (en) 1988-07-06
EP0273277A3 (en) 1989-09-13
KR880007079A (ko) 1988-08-26
IL84790A0 (en) 1988-05-31
PT86346B (pt) 1990-11-07
US4978655A (en) 1990-12-18
IL84790A (en) 1993-03-15
NZ222935A (en) 1990-09-26
DE3780016T2 (de) 1992-12-24
ES2038650T3 (es) 1993-08-01
IE873245L (en) 1988-06-17
GR3005691T3 (fi) 1993-06-07
AU8090087A (en) 1988-06-23
PH26380A (en) 1992-06-01
EG19157A (en) 1994-09-29
LU88822I2 (fr) 1997-01-06
ATE77554T1 (de) 1992-07-15
DK174627B1 (da) 2003-07-28
DK557087A (da) 1988-06-18
DE3780016D1 (de) 1992-07-30
CA1293447C (en) 1991-12-24
JPS63215632A (ja) 1988-09-08
HK55896A (en) 1996-04-03
NL960024I1 (nl) 1996-12-02
AU593405B2 (en) 1990-02-08

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