ZA875378B - Purified fetal thymidine kinase - Google Patents
Purified fetal thymidine kinaseInfo
- Publication number
- ZA875378B ZA875378B ZA875378A ZA875378A ZA875378B ZA 875378 B ZA875378 B ZA 875378B ZA 875378 A ZA875378 A ZA 875378A ZA 875378 A ZA875378 A ZA 875378A ZA 875378 B ZA875378 B ZA 875378B
- Authority
- ZA
- South Africa
- Prior art keywords
- purified
- thymidine kinase
- thymidine
- purified fetal
- relates
- Prior art date
Links
- 102000006601 Thymidine Kinase Human genes 0.000 title abstract 2
- 108020004440 Thymidine kinase Proteins 0.000 title abstract 2
- 230000001605 fetal effect Effects 0.000 title 1
- IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940104230 thymidine Drugs 0.000 abstract 2
- DWRXFEITVBNRMK-UHFFFAOYSA-N Beta-D-1-Arabinofuranosylthymine Natural products O=C1NC(=O)C(C)=CN1C1C(O)C(O)C(CO)O1 DWRXFEITVBNRMK-UHFFFAOYSA-N 0.000 abstract 1
- IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
- C12N9/1211—Thymidine kinase (2.7.1.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8611101A FR2602242B1 (fr) | 1986-07-31 | 1986-07-31 | Thymidine kinase de type foetal purifiee |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA875378B true ZA875378B (en) | 1988-01-29 |
Family
ID=9337917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA875378A ZA875378B (en) | 1986-07-31 | 1987-07-22 | Purified fetal thymidine kinase |
Country Status (14)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69432645T2 (de) * | 1993-08-06 | 2004-04-08 | Brigham Young University Technology Transfer Office, Provo | Monoklonale antikörper gegen isozyme der thymidinkinase |
| SE9401380D0 (sv) * | 1994-04-22 | 1994-04-22 | Sven Skog | Ny celltillväxt-relaterad peptid och användning därav |
| CN1301821A (zh) * | 1999-12-27 | 2001-07-04 | 上海博德基因开发有限公司 | 一种新的多肽——胸腺嘧啶核苷酸激酶11和编码这种多肽的多核苷酸 |
| US7311906B2 (en) | 2004-04-30 | 2007-12-25 | Brigham Young University | Anti-viral activity of an anti-thymidine kinase monoclonal antibody |
| US7837998B2 (en) | 2004-05-21 | 2010-11-23 | Nathaniel Lallatin | Anti-cancer activity of an anti-thymidine kinase monoclonal antibody |
| US8551486B2 (en) | 2004-05-21 | 2013-10-08 | Savoy Pharmaceuticals, Inc. | Monoclonal antibodies to human thymidine kinase to treat cancer |
| US9267948B2 (en) | 2009-12-30 | 2016-02-23 | Brigham Young University | Compositions and methods for cancer management using antibodies binding to nucleotide salvage pathway enzymes and complexes thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2028588A1 (de) * | 1970-06-10 | 1971-12-16 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur Gewinnung von Thymidin-Kinase |
-
1986
- 1986-07-31 FR FR8611101A patent/FR2602242B1/fr not_active Expired
-
1987
- 1987-07-22 ZA ZA875378A patent/ZA875378B/xx unknown
- 1987-07-24 DE DE8787401729T patent/DE3774025D1/de not_active Expired - Lifetime
- 1987-07-24 AT AT87401729T patent/ATE68821T1/de not_active IP Right Cessation
- 1987-07-24 AU AU76075/87A patent/AU594486B2/en not_active Ceased
- 1987-07-24 EP EP87401729A patent/EP0255431B1/fr not_active Expired - Lifetime
- 1987-07-24 DK DK387387A patent/DK387387A/da not_active Application Discontinuation
- 1987-07-24 ES ES198787401729T patent/ES2038681T3/es not_active Expired - Lifetime
- 1987-07-27 PT PT85406A patent/PT85406B/pt not_active IP Right Cessation
- 1987-07-29 NZ NZ221246A patent/NZ221246A/en unknown
- 1987-07-30 IE IE206487A patent/IE61237B1/en not_active IP Right Cessation
- 1987-07-30 JP JP62193612A patent/JPS6359886A/ja active Granted
- 1987-07-30 CN CN198787105215A patent/CN87105215A/zh active Pending
-
1991
- 1991-12-20 GR GR91402114T patent/GR3003416T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3774025D1 (de) | 1991-11-28 |
| DK387387D0 (da) | 1987-07-24 |
| EP0255431B1 (fr) | 1991-10-23 |
| FR2602242A1 (fr) | 1988-02-05 |
| CN87105215A (zh) | 1988-02-24 |
| IE872064L (en) | 1988-01-31 |
| AU594486B2 (en) | 1990-03-08 |
| AU7607587A (en) | 1988-02-04 |
| NZ221246A (en) | 1991-05-28 |
| IE61237B1 (en) | 1994-10-19 |
| PT85406A (fr) | 1987-08-01 |
| JPS6359886A (ja) | 1988-03-15 |
| ATE68821T1 (de) | 1991-11-15 |
| PT85406B (pt) | 1990-04-30 |
| GR3003416T3 (en) | 1993-02-17 |
| DK387387A (da) | 1988-02-01 |
| FR2602242B1 (fr) | 1989-05-26 |
| ES2038681T3 (es) | 1993-08-01 |
| JPH0438392B2 (enrdf_load_stackoverflow) | 1992-06-24 |
| EP0255431A1 (fr) | 1988-02-03 |
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