ZA871077B - Tetracyclic quinazolinones - Google Patents

Tetracyclic quinazolinones

Info

Publication number
ZA871077B
ZA871077B ZA871077A ZA871077A ZA871077B ZA 871077 B ZA871077 B ZA 871077B ZA 871077 A ZA871077 A ZA 871077A ZA 871077 A ZA871077 A ZA 871077A ZA 871077 B ZA871077 B ZA 871077B
Authority
ZA
South Africa
Prior art keywords
quinazolinones
tetracyclic
tetracyclic quinazolinones
Prior art date
Application number
ZA871077A
Other languages
English (en)
Inventor
Goetz Eduard Hardtmann
Eduard Hardtmann Goetz
William Joseph Houlihan
Joseph Houlihan William
Rudolf Karl Andreas Giger
Karl Andreas Giger Rudolf
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA871077B publication Critical patent/ZA871077B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA871077A 1986-02-13 1987-02-13 Tetracyclic quinazolinones ZA871077B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/829,594 US4760065A (en) 1986-02-13 1986-02-13 Trifluoromethyl substituted tetracyclic quinazolin-ones having tranquilizing activity

Publications (1)

Publication Number Publication Date
ZA871077B true ZA871077B (en) 1988-09-28

Family

ID=25254954

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA871077A ZA871077B (en) 1986-02-13 1987-02-13 Tetracyclic quinazolinones

Country Status (22)

Country Link
US (1) US4760065A (ja)
JP (1) JPS62223183A (ja)
KR (1) KR870007900A (ja)
AT (1) AT390062B (ja)
AU (1) AU597936B2 (ja)
BE (1) BE1002099A3 (ja)
CH (1) CH671019A5 (ja)
DE (1) DE3702943A1 (ja)
DK (1) DK69787A (ja)
ES (1) ES2004215A6 (ja)
FI (1) FI870510A (ja)
FR (1) FR2601013A1 (ja)
GB (1) GB2186574B (ja)
GR (1) GR870232B (ja)
HU (1) HU198932B (ja)
IL (1) IL81536A0 (ja)
IT (1) IT1216790B (ja)
LU (1) LU86769A1 (ja)
NL (1) NL8700233A (ja)
NZ (1) NZ219242A (ja)
SE (1) SE8700566L (ja)
ZA (1) ZA871077B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2113115A1 (en) * 1991-07-29 1993-02-18 Vlad E. Gregor Quinazoline derivatives as acetylcholinesterase inhibitors
US6133002A (en) 1997-09-25 2000-10-17 Dsm N.V. Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives
EP2447239A1 (en) * 2010-10-29 2012-05-02 Saltigo GmbH Copper-catalysed process for the production of substituted or unsubstituted trifluormethylated aryl and heteroaryl compounds

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3280117A (en) * 1964-04-20 1966-10-18 Sandoz Ag Tricyclic quinazolinones
US3772230A (en) * 1969-05-28 1973-11-13 Sandoz Ag Polyhydro-imidazo(1,5-a)pyrimidine-3(2h)-thione and pyrido(1,2-c)pyrimidine-1-thione
US3598823A (en) * 1969-05-28 1971-08-10 Sandoz Ag Tricyclic quinazolinones
US3631046A (en) * 1969-05-28 1971-12-28 Sandoz Ag Tetracyclic quinazolin-ones
US4000275A (en) * 1969-11-24 1976-12-28 Eli Lilly And Company Immunosuppressants
BE760013A (fr) * 1969-12-18 1971-06-08 Smith Kline French Lab Imidazo et pyrimido -(2,1-b)quinazolines, leurs procedes de preparationet compositions pharmaceutiques en contenant
US3868372A (en) * 1971-07-09 1975-02-25 Sandoz Ag Organomercapto-substituted polyhydro imidazo{8 1,5-a{9 pyridenes and pyride{8 1,2-c{9 pyrimidines
US3963720A (en) * 1972-10-27 1976-06-15 Sandoz, Inc. Tetracyclic imidazo [2,1-b] quinazolinone derivatives
PH17745A (en) * 1981-09-16 1984-11-27 Sandoz Ag Trifluoromethyl substituted tricyclic quinazolinones
FR2512674B1 (fr) * 1981-09-16 1986-01-10 Sandoz Sa Nouveaux derives tricycliques de la quinazolinone, leur preparation et medicaments contenant ces derives
PH19788A (en) * 1981-09-16 1986-07-02 Sandoz Ag 1-substituted tricyclic quinazolinones,pharmaceutical composition containing same and method of use thereof
US4452787A (en) * 1981-09-16 1984-06-05 Sandoz, Inc. 1-Substituted tricyclic quinazolinones having biological activity as tranquilizers

Also Published As

Publication number Publication date
GB8702938D0 (en) 1987-03-18
DK69787A (da) 1987-08-14
SE8700566L (sv) 1987-08-14
LU86769A1 (fr) 1987-09-15
GB2186574B (en) 1990-03-28
CH671019A5 (ja) 1989-07-31
DK69787D0 (da) 1987-02-11
BE1002099A3 (fr) 1990-07-03
AU597936B2 (en) 1990-06-14
IT1216790B (it) 1990-03-14
GR870232B (en) 1987-06-12
DE3702943A1 (de) 1987-08-20
NZ219242A (en) 1990-04-26
HUT43607A (en) 1987-11-30
JPS62223183A (ja) 1987-10-01
FR2601013A1 (fr) 1988-01-08
KR870007900A (ko) 1987-09-22
NL8700233A (nl) 1987-09-01
AU6869487A (en) 1987-08-20
IT8747634A0 (it) 1987-02-12
HU198932B (en) 1989-12-28
ATA29687A (de) 1989-08-15
GB2186574A (en) 1987-08-19
IL81536A0 (en) 1987-09-16
FI870510A0 (fi) 1987-02-09
US4760065A (en) 1988-07-26
FI870510A (fi) 1987-08-14
ES2004215A6 (es) 1988-12-16
SE8700566D0 (sv) 1987-02-12
AT390062B (de) 1990-03-12

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