ZA867616B - Tetrahydro-beta-carbolines,process for their production and their use as drugs - Google Patents

Tetrahydro-beta-carbolines,process for their production and their use as drugs

Info

Publication number
ZA867616B
ZA867616B ZA867616A ZA867616A ZA867616B ZA 867616 B ZA867616 B ZA 867616B ZA 867616 A ZA867616 A ZA 867616A ZA 867616 A ZA867616 A ZA 867616A ZA 867616 B ZA867616 B ZA 867616B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
hydrogen
carbolines
tetrahydro
beta
Prior art date
Application number
ZA867616A
Other languages
English (en)
Inventor
Helmut Biere
Mogens Engelstoft
Andreas Huth
Dieter Rahtz
Ralph Schmiechen
Dieter Seidelmann
David Norman Stephens
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA867616B publication Critical patent/ZA867616B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Eyeglasses (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA867616A 1985-10-04 1986-10-06 Tetrahydro-beta-carbolines,process for their production and their use as drugs ZA867616B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853535928 DE3535928A1 (de) 1985-10-04 1985-10-04 Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA867616B true ZA867616B (en) 1987-05-27

Family

ID=6283083

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA867616A ZA867616B (en) 1985-10-04 1986-10-06 Tetrahydro-beta-carbolines,process for their production and their use as drugs

Country Status (16)

Country Link
US (1) US4855295A (ja)
EP (1) EP0217737B1 (ja)
JP (1) JPH0759580B2 (ja)
AT (1) ATE66226T1 (ja)
AU (1) AU593024B2 (ja)
CA (1) CA1269981A (ja)
DE (2) DE3535928A1 (ja)
DK (1) DK169581B1 (ja)
ES (1) ES2039360T3 (ja)
FI (1) FI864018A (ja)
GR (1) GR3002944T3 (ja)
HU (1) HU195814B (ja)
IE (1) IE58896B1 (ja)
IL (1) IL80215A0 (ja)
NO (1) NO164354C (ja)
ZA (1) ZA867616B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU652968B2 (en) * 1990-10-09 1994-09-15 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new class of gaba brain receptor ligands
FR2677024B1 (fr) * 1991-05-29 1995-03-03 Centre Nat Rech Scient Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant.
US5367077A (en) * 1992-04-08 1994-11-22 Neurogen Corporation Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands
AU664912B2 (en) * 1992-09-02 1995-12-07 Dainippon Pharmaceutical Co. Ltd. Novel 3-oxadiazolyl-1,6-naphthyridine derivatives
DE4308788A1 (de) * 1993-03-18 1994-09-22 Bayer Ag Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate
CA2140722A1 (en) * 1994-01-24 1995-07-25 Joseph A. Jakubowski Beta-carboline thromboxane synthase inhibitors
US5550118A (en) * 1994-01-31 1996-08-27 Eli Lilly And Company Polyhydronorharman synthase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES273769A1 (es) * 1961-01-18 1962-06-01 Geigy Ag J R Procedimiento para la preparaciën de nuevos derivados de amidas de acido beta-carbolin-carboxilico
NZ194747A (en) * 1979-08-29 1988-11-29 Schering Ag 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives
DE3240513A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DK149270C (da) * 1983-05-27 1986-08-25 Schering Ag Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives

Also Published As

Publication number Publication date
ATE66226T1 (de) 1991-08-15
HUT42091A (en) 1987-06-29
IE862629L (en) 1987-04-04
IL80215A0 (en) 1987-01-30
JPH0759580B2 (ja) 1995-06-28
FI864018A0 (fi) 1986-10-03
NO863962L (no) 1987-04-06
FI864018A (fi) 1987-04-05
ES2039360T3 (es) 1993-10-01
IE58896B1 (en) 1993-12-01
GR3002944T3 (en) 1993-01-25
NO164354B (no) 1990-06-18
AU6366286A (en) 1987-04-09
CA1269981A (en) 1990-06-05
DK471686A (da) 1987-04-05
EP0217737A3 (en) 1988-06-01
DK169581B1 (da) 1994-12-12
JPS62181278A (ja) 1987-08-08
NO164354C (no) 1990-09-26
NO863962D0 (no) 1986-10-03
US4855295A (en) 1989-08-08
DE3535928A1 (de) 1987-04-09
AU593024B2 (en) 1990-02-01
HU195814B (en) 1988-07-28
DK471686D0 (da) 1986-10-02
EP0217737A2 (de) 1987-04-08
DE3680850D1 (de) 1991-09-19
EP0217737B1 (de) 1991-08-14

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