FR2677024B1 - Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant. - Google Patents

Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant.

Info

Publication number
FR2677024B1
FR2677024B1 FR9106453A FR9106453A FR2677024B1 FR 2677024 B1 FR2677024 B1 FR 2677024B1 FR 9106453 A FR9106453 A FR 9106453A FR 9106453 A FR9106453 A FR 9106453A FR 2677024 B1 FR2677024 B1 FR 2677024B1
Authority
FR
France
Prior art keywords
indoles
aza
receptor ligands
compounds derived
benzodiazepine receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9106453A
Other languages
English (en)
Other versions
FR2677024A1 (fr
Inventor
Robert H Dodd
Pierre Potier
Xavier Doisy
Jean Rossier
Lia Prado De Carvalho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9106453A priority Critical patent/FR2677024B1/fr
Priority to CA002110299A priority patent/CA2110299A1/fr
Priority to EP92912278A priority patent/EP0586526A1/fr
Priority to JP4511067A priority patent/JPH06508120A/ja
Priority to PCT/FR1992/000480 priority patent/WO1992021680A1/fr
Priority to US08/142,489 priority patent/US5484793A/en
Publication of FR2677024A1 publication Critical patent/FR2677024A1/fr
Application granted granted Critical
Publication of FR2677024B1 publication Critical patent/FR2677024B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9106453A 1991-05-29 1991-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant. Expired - Lifetime FR2677024B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9106453A FR2677024B1 (fr) 1991-05-29 1991-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant.
CA002110299A CA2110299A1 (fr) 1991-05-29 1992-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments le contenant
EP92912278A EP0586526A1 (fr) 1991-05-29 1992-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments le contenant
JP4511067A JPH06508120A (ja) 1991-05-29 1992-05-29 ベンゾジアゼピンレセプターのリガンドとして６−アザインドール類から誘導された化合物とそれらを含有した薬剤
PCT/FR1992/000480 WO1992021680A1 (fr) 1991-05-29 1992-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments le contenant
US08/142,489 US5484793A (en) 1991-05-29 1992-05-29 Compounds derived from 6-azaindoles as ligands of the benzodiazepine receptor and medicaments containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9106453A FR2677024B1 (fr) 1991-05-29 1991-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant.

Publications (2)

Publication Number Publication Date
FR2677024A1 FR2677024A1 (fr) 1992-12-04
FR2677024B1 true FR2677024B1 (fr) 1995-03-03

Family

ID=9413230

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9106453A Expired - Lifetime FR2677024B1 (fr) 1991-05-29 1991-05-29 Composes derives des aza-6-indoles, ligands du recepteur des benzodiazepines et medicaments les contenant.

Country Status (6)

Country Link
US (1) US5484793A (fr)
EP (1) EP0586526A1 (fr)
JP (1) JPH06508120A (fr)
CA (1) CA2110299A1 (fr)
FR (1) FR2677024B1 (fr)
WO (1) WO1992021680A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9625398D0 (en) * 1996-12-06 1997-01-22 Merck Sharp & Dohme Method of treatment,manufacture,compositions and compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3535928A1 (de) * 1985-10-04 1987-04-09 Schering Ag Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
US5484793A (en) 1996-01-16
WO1992021680A1 (fr) 1992-12-10
JPH06508120A (ja) 1994-09-14
CA2110299A1 (fr) 1992-12-10
FR2677024A1 (fr) 1992-12-04
EP0586526A1 (fr) 1994-03-16

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