ZA863824B - New derivatives of bicyclic amino acids,a process for their preparation,agents containing them and their use - Google Patents

New derivatives of bicyclic amino acids,a process for their preparation,agents containing them and their use

Info

Publication number
ZA863824B
ZA863824B ZA863824A ZA863824A ZA863824B ZA 863824 B ZA863824 B ZA 863824B ZA 863824 A ZA863824 A ZA 863824A ZA 863824 A ZA863824 A ZA 863824A ZA 863824 B ZA863824 B ZA 863824B
Authority
ZA
South Africa
Prior art keywords
preparation
amino acids
agents containing
new derivatives
bicyclic amino
Prior art date
Application number
ZA863824A
Other languages
English (en)
Inventor
Hansjoerg Urbach
Rainer Henning
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA863824B publication Critical patent/ZA863824B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA863824A 1985-05-23 1986-05-22 New derivatives of bicyclic amino acids,a process for their preparation,agents containing them and their use ZA863824B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853518514 DE3518514A1 (de) 1985-05-23 1985-05-23 Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung

Publications (1)

Publication Number Publication Date
ZA863824B true ZA863824B (en) 1986-12-30

Family

ID=6271426

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA863824A ZA863824B (en) 1985-05-23 1986-05-22 New derivatives of bicyclic amino acids,a process for their preparation,agents containing them and their use

Country Status (21)

Country Link
US (1) US4920144A (fr)
EP (1) EP0203450B1 (fr)
JP (2) JPH0819152B2 (fr)
KR (1) KR930008630B1 (fr)
AR (1) AR246954A1 (fr)
AT (1) ATE74366T1 (fr)
AU (1) AU592565B2 (fr)
CA (1) CA1310794C (fr)
DE (2) DE3518514A1 (fr)
DK (1) DK171893B1 (fr)
ES (3) ES8800151A1 (fr)
FI (1) FI83523C (fr)
GR (1) GR861316B (fr)
HU (1) HU200784B (fr)
IE (1) IE59185B1 (fr)
IL (1) IL78865A (fr)
NO (1) NO172940C (fr)
NZ (1) NZ216246A (fr)
PH (2) PH24307A (fr)
PT (1) PT82631B (fr)
ZA (1) ZA863824B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
CN108191969B (zh) * 2018-01-19 2021-01-01 渤海大学 两种来源于大西洋鳟鱼胶原蛋白的ace抑制肽

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
WO1986000896A1 (fr) * 1984-07-30 1986-02-13 Schering Corporation PROCEDE ORIGINAL POUR LA PREPARATION DE CIS, ENDO-OCTAHYDROCYCLOPENTA ADb BDPYRROLE-2-CARBOXYLATE

Also Published As

Publication number Publication date
ATE74366T1 (de) 1992-04-15
DK238786A (da) 1986-11-24
ES8800151A1 (es) 1987-10-16
US4920144A (en) 1990-04-24
HU200784B (en) 1990-08-28
NZ216246A (en) 1989-08-29
FI862136A (fi) 1986-11-24
NO172940C (no) 1993-09-29
DE3684636D1 (de) 1992-05-07
DK171893B1 (da) 1997-08-04
FI862136A0 (fi) 1986-05-21
EP0203450B1 (fr) 1992-04-01
JPH0819152B2 (ja) 1996-02-28
AR246954A1 (es) 1994-10-31
AU5780486A (en) 1986-11-27
EP0203450A2 (fr) 1986-12-03
IE59185B1 (en) 1994-01-26
ES8802424A1 (es) 1988-06-01
PH24277A (en) 1990-05-29
FI83523C (fi) 1991-07-25
ES8801629A1 (es) 1988-02-16
ES555169A0 (es) 1987-10-16
ES557520A0 (es) 1988-06-01
PT82631B (pt) 1988-08-17
IL78865A (en) 1991-07-18
DE3518514A1 (de) 1986-11-27
DK238786D0 (da) 1986-05-22
NO862043L (no) 1986-11-24
IE861361L (en) 1986-11-23
AU592565B2 (en) 1990-01-18
HUT42506A (en) 1987-07-28
JPH0848668A (ja) 1996-02-20
JPS61271299A (ja) 1986-12-01
EP0203450A3 (en) 1989-07-26
PH24307A (en) 1990-05-29
IL78865A0 (en) 1986-09-30
ES557519A0 (es) 1988-02-16
GR861316B (en) 1986-09-19
KR930008630B1 (ko) 1993-09-11
CA1310794C (fr) 1992-11-24
KR860008974A (ko) 1986-12-19
NO172940B (no) 1993-06-21
PT82631A (de) 1986-06-01
JP2579744B2 (ja) 1997-02-12
FI83523B (fi) 1991-04-15

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