DK238786A - Bicycliske aminosyrer eller fysiologiske uskadelige salte deraf, deres fremstilling og anvendelse som laegemidler samt mellemprodukter til fremstillingen og disses fremstilling - Google Patents

Bicycliske aminosyrer eller fysiologiske uskadelige salte deraf, deres fremstilling og anvendelse som laegemidler samt mellemprodukter til fremstillingen og disses fremstilling Download PDF

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Publication number
DK238786A
DK238786A DK238786A DK238786A DK238786A DK 238786 A DK238786 A DK 238786A DK 238786 A DK238786 A DK 238786A DK 238786 A DK238786 A DK 238786A DK 238786 A DK238786 A DK 238786A
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DK
Denmark
Prior art keywords
preparation
products
amino acids
bicyclic amino
intermediate products
Prior art date
Application number
DK238786A
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English (en)
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DK238786D0 (da
DK171893B1 (da
Inventor
Hansjoerg Urbach
Rainer Henning
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK238786D0 publication Critical patent/DK238786D0/da
Publication of DK238786A publication Critical patent/DK238786A/da
Application granted granted Critical
Publication of DK171893B1 publication Critical patent/DK171893B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK238786A 1985-05-23 1986-05-22 Azabicyclooctenderivater eller fysiologisk acceptable salte deraf, deres fremstilling og anvendelse, lægemidler samt mellemprodukter til fremstilling af azabicyclooctenderivaterne DK171893B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19853518514 DE3518514A1 (de) 1985-05-23 1985-05-23 Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3518514 1985-05-23

Publications (3)

Publication Number Publication Date
DK238786D0 DK238786D0 (da) 1986-05-22
DK238786A true DK238786A (da) 1986-11-24
DK171893B1 DK171893B1 (da) 1997-08-04

Family

ID=6271426

Family Applications (1)

Application Number Title Priority Date Filing Date
DK238786A DK171893B1 (da) 1985-05-23 1986-05-22 Azabicyclooctenderivater eller fysiologisk acceptable salte deraf, deres fremstilling og anvendelse, lægemidler samt mellemprodukter til fremstilling af azabicyclooctenderivaterne

Country Status (21)

Country Link
US (1) US4920144A (da)
EP (1) EP0203450B1 (da)
JP (2) JPH0819152B2 (da)
KR (1) KR930008630B1 (da)
AR (1) AR246954A1 (da)
AT (1) ATE74366T1 (da)
AU (1) AU592565B2 (da)
CA (1) CA1310794C (da)
DE (2) DE3518514A1 (da)
DK (1) DK171893B1 (da)
ES (3) ES8800151A1 (da)
FI (1) FI83523C (da)
GR (1) GR861316B (da)
HU (1) HU200784B (da)
IE (1) IE59185B1 (da)
IL (1) IL78865A (da)
NO (1) NO172940C (da)
NZ (1) NZ216246A (da)
PH (2) PH24307A (da)
PT (1) PT82631B (da)
ZA (1) ZA863824B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
CN108191969B (zh) * 2018-01-19 2021-01-01 渤海大学 两种来源于大西洋鳟鱼胶原蛋白的ace抑制肽

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
CA1244041A (en) * 1984-07-30 1988-11-01 Elijah H. Gold Process for the preparation of cis, endo- octahydrocyclopenta¬b|pyrrole-2-carboxylate

Also Published As

Publication number Publication date
FI83523C (fi) 1991-07-25
DK238786D0 (da) 1986-05-22
NO172940C (no) 1993-09-29
AR246954A1 (es) 1994-10-31
GR861316B (en) 1986-09-19
HU200784B (en) 1990-08-28
NO172940B (no) 1993-06-21
PH24307A (en) 1990-05-29
IL78865A0 (en) 1986-09-30
FI862136A0 (fi) 1986-05-21
ZA863824B (en) 1986-12-30
IE861361L (en) 1986-11-23
CA1310794C (en) 1992-11-24
DE3518514A1 (de) 1986-11-27
ATE74366T1 (de) 1992-04-15
NZ216246A (en) 1989-08-29
KR860008974A (ko) 1986-12-19
JPS61271299A (ja) 1986-12-01
FI862136A (fi) 1986-11-24
ES8801629A1 (es) 1988-02-16
IE59185B1 (en) 1994-01-26
ES557519A0 (es) 1988-02-16
DE3684636D1 (de) 1992-05-07
EP0203450A3 (en) 1989-07-26
EP0203450A2 (de) 1986-12-03
EP0203450B1 (de) 1992-04-01
PH24277A (en) 1990-05-29
NO862043L (no) 1986-11-24
AU5780486A (en) 1986-11-27
ES555169A0 (es) 1987-10-16
US4920144A (en) 1990-04-24
ES8800151A1 (es) 1987-10-16
KR930008630B1 (ko) 1993-09-11
PT82631A (de) 1986-06-01
HUT42506A (en) 1987-07-28
ES557520A0 (es) 1988-06-01
PT82631B (pt) 1988-08-17
JPH0819152B2 (ja) 1996-02-28
JP2579744B2 (ja) 1997-02-12
FI83523B (fi) 1991-04-15
IL78865A (en) 1991-07-18
DK171893B1 (da) 1997-08-04
JPH0848668A (ja) 1996-02-20
ES8802424A1 (es) 1988-06-01
AU592565B2 (en) 1990-01-18

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired