ZA85910B - A novel anhydrous,stable,crystalline o-form of prazosin hydrochloride and a novel process for the preparation of said crystalline o-form - Google Patents
A novel anhydrous,stable,crystalline o-form of prazosin hydrochloride and a novel process for the preparation of said crystalline o-formInfo
- Publication number
- ZA85910B ZA85910B ZA85910A ZA85910A ZA85910B ZA 85910 B ZA85910 B ZA 85910B ZA 85910 A ZA85910 A ZA 85910A ZA 85910 A ZA85910 A ZA 85910A ZA 85910 B ZA85910 B ZA 85910B
- Authority
- ZA
- South Africa
- Prior art keywords
- crystalline
- novel
- stable
- preparation
- prazosin hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI842544A FI79107C (fi) | 1984-06-25 | 1984-06-25 | Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA85910B true ZA85910B (en) | 1985-09-25 |
Family
ID=8519293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA85910A ZA85910B (en) | 1984-06-25 | 1985-02-06 | A novel anhydrous,stable,crystalline o-form of prazosin hydrochloride and a novel process for the preparation of said crystalline o-form |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4739055A (show.php) |
| JP (1) | JPS6115881A (show.php) |
| AT (1) | AT389117B (show.php) |
| AU (1) | AU566814B2 (show.php) |
| BE (1) | BE900925A (show.php) |
| CH (1) | CH661045A5 (show.php) |
| DE (1) | DE3429415A1 (show.php) |
| FI (1) | FI79107C (show.php) |
| FR (1) | FR2567124B1 (show.php) |
| GB (1) | GB2160861B (show.php) |
| IL (1) | IL73267A (show.php) |
| IT (1) | IT1224142B (show.php) |
| LU (1) | LU85616A1 (show.php) |
| NL (1) | NL8403250A (show.php) |
| NZ (1) | NZ209962A (show.php) |
| PT (1) | PT79411B (show.php) |
| ZA (1) | ZA85910B (show.php) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE72244T1 (de) * | 1986-03-21 | 1992-02-15 | Heumann Pharma Gmbh & Co | Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung. |
| JP2756846B2 (ja) * | 1989-12-28 | 1998-05-25 | 住化ファインケム株式会社 | 無水のε型結晶体２―〔４―（２―フロイル）ピペラジン―１―イル〕―４―アミノ―６，７―ジメトキシキナゾリン塩酸塩及びその製造方法 |
| JPH07206857A (ja) * | 1993-12-28 | 1995-08-08 | Synthelabo Sa | アルフゾシン塩酸塩の二水和物 |
| EP1757606B1 (de) * | 2001-02-24 | 2009-05-06 | Boehringer Ingelheim Pharma GmbH & Co. KG | Xanthinderivate Verwendung als Arzneimittel sowie deren Verfahren zur deren Herstellung |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US7501426B2 (en) * | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| AU2007247190A1 (en) * | 2006-05-04 | 2007-11-15 | Boehringer Ingelheim International Gmbh | Polymorphs |
| PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| JP5769966B2 (ja) * | 2007-08-17 | 2015-08-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｆａｂ関連疾患治療用プリン誘導体 |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| PE20100156A1 (es) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
| KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| EA031225B1 (ru) * | 2008-08-15 | 2018-12-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Ингибиторы дпп-4 для заживления ран |
| KR20110067096A (ko) | 2008-09-10 | 2011-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 및 관련 상태를 치료하기 위한 병용 요법 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| TWI508965B (zh) | 2008-12-23 | 2015-11-21 | Boehringer Ingelheim Int | 有機化合物的鹽形式 |
| TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
| EA034869B1 (ru) | 2009-11-27 | 2020-03-31 | Бёрингер Ингельхайм Интернациональ Гмбх | Лечение генотипированных пациентов с диабетом ингибиторами дпп-4, такими как линаглиптин |
| NZ602921A (en) | 2010-05-05 | 2016-01-29 | Boehringer Ingelheim Int | Combination therapy comprising the administration of a glp-1 receptor agonist and a ddp-4 inhibitor |
| KR20220025926A (ko) | 2010-06-24 | 2022-03-03 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
| AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
| CA2841552C (en) | 2011-07-15 | 2020-06-23 | Boehringer Ingelheim International Gmbh | Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| WO2013171167A1 (en) | 2012-05-14 | 2013-11-21 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
| EP2849754B1 (en) | 2012-05-14 | 2022-09-14 | Boehringer Ingelheim International GmbH | Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| US9526728B2 (en) | 2014-02-28 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Medical use of a DPP-4 inhibitor |
| CN109310697A (zh) | 2016-06-10 | 2019-02-05 | 勃林格殷格翰国际有限公司 | 利格列汀和二甲双胍的组合 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2969375A (en) * | 1961-01-24 | Certification of correction | ||
| DE156532C (show.php) * | ||||
| NL54420C (show.php) * | 1937-05-25 | |||
| GB1156973A (en) * | 1965-07-06 | 1969-07-02 | Quinazoline Derivatives | |
| US3433788A (en) * | 1966-04-27 | 1969-03-18 | Union Carbide Corp | Process for recovery of amines from aqueous solutions by solvent treatment and distillation |
| US3421983A (en) * | 1967-03-07 | 1969-01-14 | Lummus Co | Azeotropic distillation of aqueous toluene diamine |
| US3511836A (en) * | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
| US3743672A (en) * | 1970-05-27 | 1973-07-03 | Halcon International Inc | Separation of water in alkylene glycol mono and diester purification by azeotropic distillation |
| GB1308718A (en) * | 1970-07-01 | 1973-03-07 | Sir Soc Italiana Resine Spa | Method of separating vinyl acetate from liquid mixtures |
| IT956765B (it) * | 1972-06-22 | 1973-10-10 | Montedison Spa | Procedimento per la purificazione di 1 3 diossolano |
| US3935213A (en) * | 1973-12-05 | 1976-01-27 | Pfizer Inc. | Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives |
| US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
| US4001237A (en) * | 1976-02-18 | 1977-01-04 | Bristol-Myers Company | Oxazole, isoxazole, thiazole and isothiazole amides |
| US4092315A (en) * | 1976-03-01 | 1978-05-30 | Pfizer Inc. | Novel crystalline forms of prazosin hydrochloride |
| FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
| FI64367C (fi) * | 1980-02-26 | 1986-08-05 | Orion Yhtymae Oy | Foerfarande foer framstaellning av alfa-form av prazosinhydroklorid |
-
1984
- 1984-06-25 FI FI842544A patent/FI79107C/fi not_active IP Right Cessation
- 1984-08-09 DE DE19843429415 patent/DE3429415A1/de active Granted
- 1984-10-03 GB GB08424999A patent/GB2160861B/en not_active Expired
- 1984-10-15 US US06/660,871 patent/US4739055A/en not_active Expired - Lifetime
- 1984-10-19 IL IL73267A patent/IL73267A/xx not_active IP Right Cessation
- 1984-10-19 AU AU34510/84A patent/AU566814B2/en not_active Ceased
- 1984-10-23 NZ NZ209962A patent/NZ209962A/en unknown
- 1984-10-24 IT IT23292/84A patent/IT1224142B/it active
- 1984-10-25 NL NL8403250A patent/NL8403250A/nl not_active Application Discontinuation
- 1984-10-26 PT PT79411A patent/PT79411B/pt not_active IP Right Cessation
- 1984-10-26 CH CH5142/84A patent/CH661045A5/de not_active IP Right Cessation
- 1984-10-26 FR FR8416401A patent/FR2567124B1/fr not_active Expired - Lifetime
- 1984-10-29 LU LU85616A patent/LU85616A1/fr unknown
- 1984-10-29 JP JP59227640A patent/JPS6115881A/ja active Granted
- 1984-10-29 BE BE0/213911A patent/BE900925A/fr not_active IP Right Cessation
- 1984-10-30 AT AT0344184A patent/AT389117B/de not_active IP Right Cessation
-
1985
- 1985-02-06 ZA ZA85910A patent/ZA85910B/xx unknown
-
1988
- 1988-02-08 US US07/153,780 patent/US4873330A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IT1224142B (it) | 1990-09-26 |
| FI79107B (fi) | 1989-07-31 |
| AU566814B2 (en) | 1987-10-29 |
| IL73267A0 (en) | 1985-01-31 |
| US4739055A (en) | 1988-04-19 |
| CH661045A5 (de) | 1987-06-30 |
| AT389117B (de) | 1989-10-25 |
| FI842544A0 (fi) | 1984-06-25 |
| AU3451084A (en) | 1986-01-02 |
| NZ209962A (en) | 1987-06-30 |
| FI79107C (fi) | 1989-11-10 |
| PT79411B (en) | 1986-09-15 |
| FR2567124B1 (fr) | 1990-09-21 |
| IT8423292A0 (it) | 1984-10-24 |
| GB2160861A (en) | 1986-01-02 |
| IL73267A (en) | 1988-06-30 |
| GB8424999D0 (en) | 1984-11-07 |
| NL8403250A (nl) | 1986-01-16 |
| DE3429415C2 (show.php) | 1990-05-03 |
| US4873330A (en) | 1989-10-10 |
| PT79411A (en) | 1984-11-01 |
| DE3429415A1 (de) | 1986-01-02 |
| ATA344184A (de) | 1989-03-15 |
| JPS6115881A (ja) | 1986-01-23 |
| JPH0481993B2 (show.php) | 1992-12-25 |
| GB2160861B (en) | 1987-11-18 |
| FI842544L (fi) | 1985-12-26 |
| LU85616A1 (fr) | 1985-06-04 |
| BE900925A (fr) | 1985-02-15 |
| FR2567124A1 (fr) | 1986-01-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA85910B (en) | A novel anhydrous,stable,crystalline o-form of prazosin hydrochloride and a novel process for the preparation of said crystalline o-form | |
| HUT44257A (en) | Process for preparing crystalline cefalosporinhydrate | |
| YU191188A (en) | Process for preparing new ammonia compounds | |
| PT79963A (en) | Process for the preparation of asymetric diesthers | |
| CY1565A (en) | Novel pleuromutilin derivatives,process for their production and their use | |
| ZA862929B (en) | Process for preparing(z)-1-phenyl-1-diethylaminocarbonyl-2-aminomethyl-cyclopropane hydrochloride | |
| PL256373A1 (en) | Process for preparing silibinin,free of isosilibin | |
| DE3571028D1 (en) | A process for the preparation of p-isononanoyloxybenzenenesulphonate | |
| YU228688A (en) | Process for preparing new ammonia compounds | |
| PT81522B (en) | Process for preparing basic v1-vasopressin antagonists | |
| ZW19887A1 (en) | Process for preparing urea | |
| DE3665875D1 (en) | Crystalline polyester-imides, process for production thereof, and use thereof | |
| CS690485A2 (en) | Process for preparing aminoalcohols | |
| PT81510A (en) | Process for preparing v1-vasopressin antagonists | |
| PT85372A (en) | Bisucaderin a process for producing this compound and its use as a medicament | |
| YU45030B (en) | Process for preparing crystalline cimetidine | |
| IL84403A (en) | Process for the preparation of a nitrobenzoylalkane-sulfonamide | |
| DE3561057D1 (en) | Process for preparing 1-naphthyl amine | |
| DE3564274D1 (en) | Novel ethyl benzylphosphinate derivatives, process for production thereof, and their use as calcium antagonist | |
| HUT46594A (en) | Process for producing ammonia | |
| YU5488A (en) | Process for producing herbicidal pyridinsulphonyl ureas | |
| EP0253360A3 (en) | Process for preparing nitriles | |
| EP0265931A3 (en) | Process for the preparation of alkylaniline using a friedel-crafts-catalysator | |
| YU44938B (en) | Process for preparing crystalline cimetidine | |
| PT81197B (en) | Process for preparing 5,6-dialkoxy-4-alkyl-2(1h)-quinazolinones |