ZA858416B - A therapeutically useful compound - Google Patents

A therapeutically useful compound

Info

Publication number
ZA858416B
ZA858416B ZA858416A ZA858416A ZA858416B ZA 858416 B ZA858416 B ZA 858416B ZA 858416 A ZA858416 A ZA 858416A ZA 858416 A ZA858416 A ZA 858416A ZA 858416 B ZA858416 B ZA 858416B
Authority
ZA
South Africa
Prior art keywords
therapeutically useful
useful compound
imidazole
benzyl
dimethyl
Prior art date
Application number
ZA858416A
Other languages
English (en)
Inventor
Raimo Einari Virtanen
Arto Johannes Karjalainen
Kauko Oiva Antero Kurkela
Antti Tapani Vaehae-Vahe
Outi Maritta Vainio-Kivinen
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of ZA858416B publication Critical patent/ZA858416B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Stringed Musical Instruments (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA858416A 1984-12-04 1985-11-01 A therapeutically useful compound ZA858416B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI844786A FI844786A0 (fi) 1984-12-04 1984-12-04 Terapeutiskt utnyttjbar foerening.

Publications (1)

Publication Number Publication Date
ZA858416B true ZA858416B (en) 1986-07-30

Family

ID=8520010

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA858416A ZA858416B (en) 1984-12-04 1985-11-01 A therapeutically useful compound

Country Status (11)

Country Link
US (1) US4670455A (enExample)
EP (1) EP0187471B1 (enExample)
JP (1) JPS61134314A (enExample)
AT (1) ATE65694T1 (enExample)
AU (1) AU572364B2 (enExample)
DE (1) DE3583670D1 (enExample)
DK (1) DK163960C (enExample)
FI (1) FI844786A0 (enExample)
IE (1) IE58269B1 (enExample)
NZ (1) NZ213604A (enExample)
ZA (1) ZA858416B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI864570A0 (fi) * 1986-11-11 1986-11-11 Farmos Oy Terapeutiskt anvaendbar foerening.
GB2206880B (en) 1987-07-16 1991-04-24 Farmos Oy Optical isomers of an imidazole derivative
GB2215206B (en) 1988-02-29 1991-07-03 Farmos Oy 4-substituted imidazole derivatives useful in perioperative care
US5344840A (en) * 1988-02-29 1994-09-06 Orion-Yhtyma Oy 4-substituted imidazole derivatives useful in perioperative care
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
FI20041425A0 (fi) * 2004-11-05 2004-11-05 Orion Corp Transmukosaalinen veterinäärinen koostumus
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
US20100196286A1 (en) * 2008-12-01 2010-08-05 Armer Thomas A Inhalation delivery methods and devices
WO2010074753A1 (en) 2008-12-23 2010-07-01 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
WO2013069025A1 (en) 2011-11-11 2013-05-16 Neon Laboratories Ltd. "process for the preparation of dexmedetomidine"
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
EP3054930B1 (en) 2013-10-07 2020-12-02 Teikoku Pharma USA, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
TWI645866B (zh) 2013-10-07 2019-01-01 美商帝國製藥美國股份有限公司 右美托咪啶經皮輸送裝置及使用其之方法
EP3054935B1 (en) 2013-10-07 2020-12-09 Teikoku Pharma USA, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
US9717796B1 (en) 2016-04-20 2017-08-01 Slypharma, Llc Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container
PL3562486T3 (pl) 2016-12-31 2024-09-16 Bioxcel Therapeutics, Inc. Zastosowanie podjęzykowo deksmedetomidyny w leczeniu pobudzenia
CN112888431B (zh) 2018-06-27 2022-06-03 比奥克斯塞尔医疗股份有限公司 含右美托咪定的膜制剂及其制造方法
US11160791B2 (en) 2018-11-01 2021-11-02 Medefil, Inc. Dexmedetomidine injection premix formulation in ready to use (RTU) bags
CN114375191A (zh) 2019-07-19 2022-04-19 比奥克斯塞尔医疗股份有限公司 非镇静的右美托咪定治疗方案
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use
GB2096987B (en) * 1981-04-22 1984-04-04 Farmos Oy Substituted imidazole and imidazole derivatives and their preparation and use
GB2101114B (en) * 1981-07-10 1985-05-22 Farmos Group Ltd Substituted imidazole derivatives and their preparation and use
NZ205247A (en) * 1982-08-14 1987-03-31 Wellcome Found Imidazoles and pharmaceutical compositions

Also Published As

Publication number Publication date
DE3583670D1 (de) 1991-09-05
AU572364B2 (en) 1988-05-05
EP0187471A2 (en) 1986-07-16
ATE65694T1 (de) 1991-08-15
JPS61134314A (ja) 1986-06-21
DK163960C (da) 1992-09-21
DK508985D0 (da) 1985-11-05
IE58269B1 (en) 1993-08-25
IE853024L (en) 1986-06-04
EP0187471B1 (en) 1991-07-31
DK163960B (da) 1992-04-27
DK508985A (da) 1986-06-05
FI844786A0 (fi) 1984-12-04
US4670455A (en) 1987-06-02
EP0187471A3 (en) 1988-09-14
JPH0465050B2 (enExample) 1992-10-16
AU4997185A (en) 1986-06-12
NZ213604A (en) 1988-09-29

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