ZA856944B - 7-(2-aminoethyl)-1,3-benzthia-or oxa-zol-2(3h)-ones - Google Patents

7-(2-aminoethyl)-1,3-benzthia-or oxa-zol-2(3h)-ones

Info

Publication number
ZA856944B
ZA856944B ZA856944A ZA856944A ZA856944B ZA 856944 B ZA856944 B ZA 856944B ZA 856944 A ZA856944 A ZA 856944A ZA 856944 A ZA856944 A ZA 856944A ZA 856944 B ZA856944 B ZA 856944B
Authority
ZA
South Africa
Prior art keywords
benzthia
zol
oxa
aminoethyl
ones
Prior art date
Application number
ZA856944A
Other languages
English (en)
Inventor
Orum David Stringer
Joseph Weinstock
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of ZA856944B publication Critical patent/ZA856944B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA856944A 1984-09-12 1985-09-11 7-(2-aminoethyl)-1,3-benzthia-or oxa-zol-2(3h)-ones ZA856944B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/649,466 US4554284A (en) 1984-09-12 1984-09-12 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones

Publications (1)

Publication Number Publication Date
ZA856944B true ZA856944B (en) 1986-06-25

Family

ID=24604912

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA856944A ZA856944B (en) 1984-09-12 1985-09-11 7-(2-aminoethyl)-1,3-benzthia-or oxa-zol-2(3h)-ones

Country Status (10)

Country Link
US (1) US4554284A (da)
EP (1) EP0174811A3 (da)
JP (1) JPS6168476A (da)
AU (1) AU581020B2 (da)
CA (1) CA1248115A (da)
DK (1) DK413585A (da)
ES (1) ES8700663A1 (da)
GR (1) GR852175B (da)
PT (1) PT81110B (da)
ZA (1) ZA856944B (da)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1183453B (it) * 1985-03-01 1987-10-22 Minnesota Mining & Mfg Copulanti 2-equivalenti formatori di colorante cian 5-idrossi-6-acilammino-benzossazol-2-one, elementi fotografici agli alogenuri d'argento e procedimentiche li impiegano
US4720297A (en) * 1985-09-27 1988-01-19 Sumitomo Chemical Company, Limited Benzothiazolones, and their production and use as herbicides
JPS62277347A (ja) * 1986-02-25 1987-12-02 Microbial Chem Res Found 新規生理活性物質ア−ブスタチン類縁化合物
MX173362B (es) * 1987-03-02 1994-02-23 Pfizer Compuestos de piperazinil heterociclicos y procedimiento para su preparacion
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5268381A (en) * 1990-09-26 1993-12-07 Adir Et Compagnie Aminoalkyl-benzothiazolinone and -benzoxazolinone compounds having a high 5-HT1A affinity
US5234924A (en) * 1990-09-26 1993-08-10 Adir Et Compagnie Benzothiazine and benzothiazole compounds useful as analgesics
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
GB9211172D0 (en) * 1992-05-27 1992-07-08 Fisons Plc Compounds
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2717810B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
TW356468B (en) * 1995-09-15 1999-04-21 Astra Pharma Prod Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same
GB9526511D0 (en) * 1995-12-23 1996-02-28 Astra Pharma Prod Pharmaceutically active compounds
US7122019B1 (en) 2000-11-28 2006-10-17 Flowmedica Inc. Intra-aortic renal drug delivery catheter
US6749598B1 (en) 1999-01-11 2004-06-15 Flowmedica, Inc. Apparatus and methods for treating congestive heart disease
US7329236B2 (en) 1999-01-11 2008-02-12 Flowmedica, Inc. Intra-aortic renal drug delivery catheter
US7481803B2 (en) 2000-11-28 2009-01-27 Flowmedica, Inc. Intra-aortic renal drug delivery catheter
US7780628B1 (en) 1999-01-11 2010-08-24 Angiodynamics, Inc. Apparatus and methods for treating congestive heart disease
US7993325B2 (en) 2002-09-20 2011-08-09 Angio Dynamics, Inc. Renal infusion systems and methods
JP2006508776A (ja) 2002-09-20 2006-03-16 フローメディカ，インコーポレイテッド 腎臓内カテーテルを介する選択的物質送達のための方法および装置
WO2004034767A2 (en) 2002-09-20 2004-04-29 Flowmedica, Inc. Catheter system for renal therapy
AU2003294226A1 (en) 2002-09-20 2004-04-23 Flowmedica, Inc. Method and apparatus for intra aortic substance delivery to a branch vessel
US20050197624A1 (en) 2004-03-04 2005-09-08 Flowmedica, Inc. Sheath for use in peripheral interventions
US7063679B2 (en) 2002-09-20 2006-06-20 Flowmedica, Inc. Intra-aortic renal delivery catheter
EP1635736A2 (en) 2003-06-05 2006-03-22 FlowMedica, Inc. Systems and methods for performing bi-lateral interventions or diagnosis in branched body lumens
EP1750506A4 (en) 2004-05-14 2010-03-17 Flowmedica Inc BILATERAL LOCAL RENAL DELIVERY FOR THE TREATMENT OF CONGESTIVE HEART FAILURE AND BNP THERAPY
TW200738658A (en) 2005-08-09 2007-10-16 Astrazeneca Ab Novel compounds
TW200745067A (en) 2006-03-14 2007-12-16 Astrazeneca Ab Novel compounds
US7771401B2 (en) 2006-06-08 2010-08-10 Angiodynamics, Inc. Selective renal cannulation and infusion systems and methods
TW200833670A (en) 2006-12-20 2008-08-16 Astrazeneca Ab Novel compounds 569
RU2455295C2 (ru) * 2006-12-20 2012-07-10 АстраЗенека AБ 4-ГИДРОКСИ-2-ОКСО-2,3-ДИГИДРО-1,3-БЕНЗОТИАЗОЛ-7-ИЛЬНЫЕ СОЕДИНЕНИЯ ДЛЯ МОДУЛЯЦИИ β2-АДРЕНОРЕЦЕПТОРНОЙ АКТИВНОСТИ
GB0702458D0 (en) 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
WO2009154557A1 (en) 2008-06-18 2009-12-23 Astrazeneca Ab Benzoxazinone derivatives acting as beta2-adrenoreceptor agonist for the treatment of respiratory disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927352A1 (de) * 1979-07-06 1981-02-05 Thomae Gmbh Dr K In 6-stellung substituierte benzothiazol-2(3h)-one enthaltende arzneimittel
US4474965A (en) * 1980-01-25 1984-10-02 Monsanto Company 3-Substituted aminoalkyl-2-benzothiazolinones
US4314944A (en) * 1980-08-22 1982-02-09 Smithkline Corporation 4-Aminoalkyl-7-hydroxy-2(3H)-indolones
FR2491471A1 (fr) * 1980-10-03 1982-04-09 Cerm Cent Europ Rech Mauvernay Benzoxazolinones substituees, leur preparation et leur application en therapeutique
DE3134590A1 (de) * 1981-09-01 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue benzo-heterocyclen
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
FR2536749A1 (fr) * 1982-11-25 1984-06-01 Cerm Cent Europ Rech Mauvernay (amino-2 ethyl)-6 benzoxazolinones substituees, leur preparation et leurs applications en therapeutique
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones

Also Published As

Publication number Publication date
EP0174811A3 (en) 1987-09-02
ES8700663A1 (es) 1986-10-16
AU4714385A (en) 1986-03-20
US4554284A (en) 1985-11-19
CA1248115A (en) 1989-01-03
PT81110A (en) 1985-10-01
PT81110B (en) 1987-07-06
DK413585D0 (da) 1985-09-11
DK413585A (da) 1986-03-13
EP0174811A2 (en) 1986-03-19
JPS6168476A (ja) 1986-04-08
ES546886A0 (es) 1986-10-16
GR852175B (da) 1986-01-10
AU581020B2 (en) 1989-02-09

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