ZA854901B - Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives - Google Patents

Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives

Info

Publication number
ZA854901B
ZA854901B ZA854901A ZA854901A ZA854901B ZA 854901 B ZA854901 B ZA 854901B ZA 854901 A ZA854901 A ZA 854901A ZA 854901 A ZA854901 A ZA 854901A ZA 854901 B ZA854901 B ZA 854901B
Authority
ZA
South Africa
Prior art keywords
thia
azabicyclo
hept
oxo
antibacterial
Prior art date
Application number
ZA854901A
Other languages
English (en)
Inventor
Barry Clive Ross
Andrew John Barker
Nicholas Iain Carruthers
Michael David Cooke
Original Assignee
Hoechst Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Uk Ltd filed Critical Hoechst Uk Ltd
Publication of ZA854901B publication Critical patent/ZA854901B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/90Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl and carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896Compounds having one or more Si-O-acyl linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA854901A 1984-06-29 1985-06-28 Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives ZA854901B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848416565A GB8416565D0 (en) 1984-06-29 1984-06-29 Antibacterial derivatives

Publications (1)

Publication Number Publication Date
ZA854901B true ZA854901B (en) 1986-02-26

Family

ID=10563160

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA854901A ZA854901B (en) 1984-06-29 1985-06-28 Antibacterial 7-oxo-4-thia-1-azabicyclo(3,2,0)hept-2-ene derivatives

Country Status (17)

Country Link
US (1) US4795748A (es)
EP (1) EP0170028A1 (es)
JP (1) JPS6118760A (es)
KR (1) KR860000300A (es)
AU (1) AU583521B2 (es)
DK (1) DK296085A (es)
ES (11) ES8707963A1 (es)
FI (1) FI852554L (es)
GB (2) GB8416565D0 (es)
GR (1) GR851584B (es)
HU (3) HU196748B (es)
IL (1) IL75675A0 (es)
NO (3) NO852356L (es)
NZ (1) NZ212572A (es)
PH (1) PH22117A (es)
PT (1) PT80736B (es)
ZA (1) ZA854901B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2195627A (en) * 1986-08-12 1988-04-13 Hoechst Uk Ltd Penem derivatives
ES2058328T3 (es) * 1987-02-11 1994-11-01 Ciba Geigy Ag Acidos beta-lactama carboxilicos biciclicos.
AT392903B (de) * 1987-10-08 1991-07-10 Hoechst Ag Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum
SE535691C2 (sv) 2011-03-08 2012-11-13 Kat2Biz Ab Reduktion av C-O-bindningar via katalytisk transfer hydrogenolys
CA2887296C (en) * 2012-10-12 2018-12-04 Eli Lilly And Company Chemical engines and methods for their use, especially in the injection of highly viscous fluids
WO2018152018A1 (en) 2017-02-17 2018-08-23 Eli Lilly And Company Processes and devices for delivery of fluid by chemical reaction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
ES8305366A1 (es) * 1981-07-08 1983-04-01 Hoechst Uk Ltd "procedimiento para la preparacion de derivados de penem".
DE3274982D1 (en) * 1981-07-08 1987-02-12 Hoechst Uk Ltd Antibacterial penem derivatives
GR78890B (es) * 1982-07-08 1984-10-02 Hoechst Uk Ltd
GB2164334B (en) * 1984-09-10 1988-08-03 Hoechst Uk Ltd Antibacterial 7-oxo-4-thia-1-azabicyclo 3,2,0 hept-2-ene derivativess

Also Published As

Publication number Publication date
DK296085D0 (da) 1985-06-28
ES557535A0 (es) 1988-02-16
HU196748B (en) 1989-01-30
ES551562A0 (es) 1988-02-16
ES8707496A1 (es) 1987-08-01
ES8707963A1 (es) 1987-09-01
ES8707539A1 (es) 1987-08-01
ES557091A0 (es) 1987-08-01
ES557088A0 (es) 1987-08-01
ES557086A0 (es) 1987-08-01
NO852356L (no) 1985-12-30
JPS6118760A (ja) 1986-01-27
HUT37942A (en) 1986-03-28
ES557092A0 (es) 1987-12-01
GB2161161A (en) 1986-01-08
ES8707498A1 (es) 1987-08-01
ES8801660A1 (es) 1988-02-16
AU583521B2 (en) 1989-05-04
GB8416565D0 (en) 1984-08-01
ES8707497A1 (es) 1987-08-01
FI852554A0 (fi) 1985-06-27
NO860974L (no) 1985-12-30
AU4440885A (en) 1986-01-02
ES8800898A1 (es) 1987-12-01
GB2161161B (en) 1989-05-24
US4795748A (en) 1989-01-03
ES8801661A1 (es) 1988-02-16
IL75675A0 (en) 1985-10-31
FI852554L (fi) 1985-12-30
HU196809B (en) 1989-01-30
ES544625A0 (es) 1987-09-01
ES557089A0 (es) 1987-08-01
GB8516493D0 (en) 1985-07-31
ES8707540A1 (es) 1987-08-01
EP0170028A1 (en) 1986-02-05
DK296085A (da) 1985-12-30
PT80736A (en) 1985-10-01
GR851584B (es) 1985-11-25
NO860975L (no) 1985-12-30
PH22117A (en) 1988-06-01
ES557090A0 (es) 1987-08-01
ES9000004A1 (es) 1988-12-16
HU194890B (en) 1988-03-28
ES8707495A1 (es) 1987-08-01
ES551561A0 (es) 1988-12-16
NZ212572A (en) 1989-02-24
PT80736B (en) 1987-03-17
KR860000300A (ko) 1986-01-27
ES557087A0 (es) 1987-08-01

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