ZA847440B - Insulin derivatives modified in the b30 position,processes for their preparation and their use,and pharmaceutical agents for the treatment of diabetes mellitus - Google Patents
Insulin derivatives modified in the b30 position,processes for their preparation and their use,and pharmaceutical agents for the treatment of diabetes mellitusInfo
- Publication number
- ZA847440B ZA847440B ZA847440A ZA847440A ZA847440B ZA 847440 B ZA847440 B ZA 847440B ZA 847440 A ZA847440 A ZA 847440A ZA 847440 A ZA847440 A ZA 847440A ZA 847440 B ZA847440 B ZA 847440B
- Authority
- ZA
- South Africa
- Prior art keywords
- des
- group
- human insulin
- phe
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833334407 DE3334407A1 (de) | 1983-09-23 | 1983-09-23 | In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA847440B true ZA847440B (en) | 1985-05-29 |
Family
ID=6209839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA847440A ZA847440B (en) | 1983-09-23 | 1984-09-21 | Insulin derivatives modified in the b30 position,processes for their preparation and their use,and pharmaceutical agents for the treatment of diabetes mellitus |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0137361B1 (xx) |
| JP (1) | JPS6094999A (xx) |
| KR (1) | KR850002287A (xx) |
| AT (1) | ATE52791T1 (xx) |
| AU (1) | AU573624B2 (xx) |
| CA (1) | CA1247545A (xx) |
| DE (2) | DE3334407A1 (xx) |
| DK (1) | DK172632B1 (xx) |
| ES (1) | ES8505647A1 (xx) |
| FI (1) | FI843695L (xx) |
| GR (1) | GR80441B (xx) |
| HU (1) | HUT36843A (xx) |
| IE (1) | IE57669B1 (xx) |
| IL (1) | IL73021A (xx) |
| NO (1) | NO843799L (xx) |
| NZ (1) | NZ209620A (xx) |
| PT (1) | PT79249A (xx) |
| ZA (1) | ZA847440B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3326472A1 (de) * | 1983-07-22 | 1985-02-14 | Hoechst Ag, 6230 Frankfurt | Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus |
| DE3327928A1 (de) * | 1983-08-03 | 1985-02-21 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von insulin-derivaten |
| DE3333640A1 (de) * | 1983-09-17 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung |
| DE3827533A1 (de) * | 1988-08-13 | 1990-02-15 | Hoechst Ag | Pharmazeutische zubereitung zur behandlung des diabetes mellitus |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2069502A (en) * | 1936-04-21 | 1937-02-02 | American Floor Surfacing Mach | Sanderplane |
| US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| DE2433883C2 (de) * | 1973-07-20 | 1986-03-27 | Research Corp., New York, N.Y. | Verwendung von physiologisch aktiven Polypeptiden |
| DK147437A (en) * | 1980-02-11 | 1900-01-01 | Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof | |
| JPS5767548A (en) * | 1980-10-14 | 1982-04-24 | Shionogi & Co Ltd | Insulin analog and its preparation |
| DE3101382A1 (de) * | 1981-01-17 | 1982-09-02 | Hoechst Ag, 6000 Frankfurt | "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten" |
| DE3333640A1 (de) * | 1983-09-17 | 1985-04-25 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung |
-
1983
- 1983-09-23 DE DE19833334407 patent/DE3334407A1/de not_active Withdrawn
-
1984
- 1984-09-17 HU HU843491A patent/HUT36843A/hu unknown
- 1984-09-17 AT AT84111058T patent/ATE52791T1/de not_active IP Right Cessation
- 1984-09-17 DE DE8484111058T patent/DE3482265D1/de not_active Expired - Fee Related
- 1984-09-17 EP EP84111058A patent/EP0137361B1/de not_active Expired - Lifetime
- 1984-09-20 FI FI843695A patent/FI843695L/fi not_active Application Discontinuation
- 1984-09-21 IE IE2415/84A patent/IE57669B1/en not_active IP Right Cessation
- 1984-09-21 ES ES536115A patent/ES8505647A1/es not_active Expired
- 1984-09-21 ZA ZA847440A patent/ZA847440B/xx unknown
- 1984-09-21 DK DK198404530A patent/DK172632B1/da not_active IP Right Cessation
- 1984-09-21 AU AU33419/84A patent/AU573624B2/en not_active Ceased
- 1984-09-21 GR GR80441A patent/GR80441B/el unknown
- 1984-09-21 JP JP59196962A patent/JPS6094999A/ja active Pending
- 1984-09-21 NZ NZ209620A patent/NZ209620A/en unknown
- 1984-09-21 IL IL73021A patent/IL73021A/xx not_active IP Right Cessation
- 1984-09-21 NO NO843799A patent/NO843799L/no unknown
- 1984-09-21 CA CA000463810A patent/CA1247545A/en not_active Expired
- 1984-09-21 KR KR1019840005799A patent/KR850002287A/ko not_active Application Discontinuation
- 1984-09-21 PT PT79249A patent/PT79249A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU573624B2 (en) | 1988-06-16 |
| EP0137361A2 (de) | 1985-04-17 |
| ES536115A0 (es) | 1985-06-01 |
| DK453084D0 (da) | 1984-09-21 |
| GR80441B (en) | 1985-01-21 |
| CA1247545A (en) | 1988-12-28 |
| ES8505647A1 (es) | 1985-06-01 |
| EP0137361B1 (de) | 1990-05-16 |
| DK453084A (da) | 1985-03-24 |
| IE842415L (en) | 1985-03-23 |
| ATE52791T1 (de) | 1990-06-15 |
| DK172632B1 (da) | 1999-03-22 |
| FI843695A0 (fi) | 1984-09-20 |
| NZ209620A (en) | 1988-03-30 |
| IE57669B1 (en) | 1993-02-24 |
| NO843799L (no) | 1985-03-25 |
| EP0137361A3 (en) | 1987-05-06 |
| DE3334407A1 (de) | 1985-04-04 |
| DE3482265D1 (de) | 1990-06-21 |
| PT79249A (de) | 1984-10-01 |
| FI843695L (fi) | 1985-03-24 |
| AU3341984A (en) | 1985-03-28 |
| IL73021A0 (en) | 1984-12-31 |
| KR850002287A (ko) | 1985-05-10 |
| HUT36843A (en) | 1985-10-28 |
| IL73021A (en) | 1989-09-10 |
| JPS6094999A (ja) | 1985-05-28 |
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