ZA84560B - Pyrrolidinone derivatives and processes for the manufacture thereof - Google Patents

Pyrrolidinone derivatives and processes for the manufacture thereof

Info

Publication number
ZA84560B
ZA84560B ZA84560A ZA84560A ZA84560B ZA 84560 B ZA84560 B ZA 84560B ZA 84560 A ZA84560 A ZA 84560A ZA 84560 A ZA84560 A ZA 84560A ZA 84560 B ZA84560 B ZA 84560B
Authority
ZA
South Africa
Prior art keywords
manufacture
processes
pyrrolidinone derivatives
pyrrolidinone
derivatives
Prior art date
Application number
ZA84560A
Other languages
English (en)
Inventor
William Bencze
Bruno Kamber
Angelo Storni
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA84560B publication Critical patent/ZA84560B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA84560A 1983-01-27 1984-01-25 Pyrrolidinone derivatives and processes for the manufacture thereof ZA84560B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH45383 1983-01-27

Publications (1)

Publication Number Publication Date
ZA84560B true ZA84560B (en) 1984-09-26

Family

ID=4187370

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA84560A ZA84560B (en) 1983-01-27 1984-01-25 Pyrrolidinone derivatives and processes for the manufacture thereof

Country Status (12)

Country Link
EP (1) EP0115472A3 (enrdf_load_html_response)
JP (1) JPS59141559A (enrdf_load_html_response)
KR (1) KR840007571A (enrdf_load_html_response)
AU (1) AU2383884A (enrdf_load_html_response)
DD (1) DD216005A5 (enrdf_load_html_response)
DK (1) DK35884A (enrdf_load_html_response)
FI (1) FI840260L (enrdf_load_html_response)
GR (1) GR81746B (enrdf_load_html_response)
IL (1) IL70772A0 (enrdf_load_html_response)
NO (1) NO840310L (enrdf_load_html_response)
PT (1) PT78007B (enrdf_load_html_response)
ZA (1) ZA84560B (enrdf_load_html_response)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE943625C (de) * 1943-06-28 1956-05-24 Ferguson Harry Inc Seitensteuerungseinrichtung fuer ein landwirtschaftliches Schlepperanbaugeraet
JPH0696574B2 (ja) * 1987-09-16 1994-11-30 三菱化成株式会社 ４−ピペリジンカルボキサミド誘導体
JPH0696575B2 (ja) * 1987-09-17 1994-11-30 三菱化成株式会社 ４−アミノピリジン誘導体及びその酸付加塩
JP2997488B2 (ja) * 1989-12-25 2000-01-11 興研株式会社 腫瘍細胞増殖抑制剤
CA2172125A1 (en) * 1993-09-30 1995-04-06 S. Jane Desolms Inhibitors of farnesyl-protein transferase
WO2000051998A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
US20050065205A1 (en) 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
TW201206425A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Treatment of depressive disorders
JP5323481B2 (ja) 2005-07-29 2013-10-23 ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート 長期記憶を増強するための、ｐｋｃ賦活薬の単独またはｐｋｃ阻害剤と組み合わせての使用
EP2121000B1 (en) 2007-02-09 2015-09-23 Blanchette Rockefeller Neurosciences, Institute Therapeutic effects of bryostatins, bryologs, and other related substances on head trauma-induced memory impairment and brain injury

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT360980B (de) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-alkylamiden des 2-oxo-1-pyrrolidins
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams

Also Published As

Publication number Publication date
JPS59141559A (ja) 1984-08-14
DD216005A5 (de) 1984-11-28
FI840260A7 (fi) 1984-07-28
FI840260L (fi) 1984-07-28
PT78007B (en) 1986-06-18
EP0115472A3 (de) 1985-10-02
PT78007A (en) 1984-02-01
AU2383884A (en) 1984-08-02
KR840007571A (ko) 1984-12-08
DK35884A (da) 1984-07-28
IL70772A0 (en) 1984-04-30
GR81746B (enrdf_load_html_response) 1984-12-12
NO840310L (no) 1984-07-30
DK35884D0 (da) 1984-01-26
FI840260A0 (fi) 1984-01-23
EP0115472A2 (de) 1984-08-08

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