IL70772A0 - Pyrrolidinone derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents

Pyrrolidinone derivatives,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL70772A0
IL70772A0 IL70772A IL7077284A IL70772A0 IL 70772 A0 IL70772 A0 IL 70772A0 IL 70772 A IL70772 A IL 70772A IL 7077284 A IL7077284 A IL 7077284A IL 70772 A0 IL70772 A0 IL 70772A0
Authority
IL
Israel
Prior art keywords
manufacture
pharmaceutical compositions
compositions containing
pyrrolidinone derivatives
pyrrolidinone
Prior art date
Application number
IL70772A
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL70772A0 publication Critical patent/IL70772A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL70772A 1983-01-27 1984-01-25 Pyrrolidinone derivatives,their manufacture and pharmaceutical compositions containing them IL70772A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH45383 1983-01-27

Publications (1)

Publication Number Publication Date
IL70772A0 true IL70772A0 (en) 1984-04-30

Family

ID=4187370

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70772A IL70772A0 (en) 1983-01-27 1984-01-25 Pyrrolidinone derivatives,their manufacture and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0115472A3 (en)
JP (1) JPS59141559A (en)
KR (1) KR840007571A (en)
AU (1) AU2383884A (en)
DD (1) DD216005A5 (en)
DK (1) DK35884A (en)
FI (1) FI840260A (en)
GR (1) GR81746B (en)
IL (1) IL70772A0 (en)
NO (1) NO840310L (en)
PT (1) PT78007B (en)
ZA (1) ZA84560B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE943625C (en) * 1943-06-28 1956-05-24 Ferguson Harry Inc Side control device for an agricultural tractor attachment
JPH0696574B2 (en) * 1987-09-16 1994-11-30 三菱化成株式会社 4-piperidine carboxamide derivative
JPH0696575B2 (en) * 1987-09-17 1994-11-30 三菱化成株式会社 4-Aminopyridine derivative and acid addition salt thereof
JP2997488B2 (en) * 1989-12-25 2000-01-11 興研株式会社 Tumor cell growth inhibitor
JPH09504277A (en) * 1993-09-30 1997-04-28 メルク エンド カンパニー インコーポレーテッド Farnesyl-protein transferase inhibitors
WO2000051998A1 (en) 1999-03-02 2000-09-08 Boehringer Ingelheim Pharmaceuticals, Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
US6825229B2 (en) 2002-03-07 2004-11-30 Blanchette Rockefeller Neurosciences Institute Methods for Alzheimer's Disease treatment and cognitive enhancement
US20050065205A1 (en) 2002-03-07 2005-03-24 Daniel Alkon Methods for Alzheimer's disease treatment and cognitive enhance
TW201207390A (en) 2004-05-18 2012-02-16 Brni Neurosciences Inst Method for screening agent for antidepressant activity
WO2007016202A1 (en) 2005-07-29 2007-02-08 Blanchette Rockefeller Neurosciences Institute Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory
CN101848726A (en) 2007-02-09 2010-09-29 布朗歇特洛克菲勒神经科学研究所 The memory impairment that bryostatin, bryostatin analog and other related substances cause head trauma and the curative effect of brain injury

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT360980B (en) * 1976-01-14 1981-02-10 Pliva Pharm & Chem Works METHOD FOR PRODUCING N-ALKYLAMIDES OF 2-OXO-1-PYRROLIDINE
GB1539817A (en) * 1976-10-22 1979-02-07 Ucb Sa N-substituted lactams

Also Published As

Publication number Publication date
FI840260A (en) 1984-07-28
FI840260A0 (en) 1984-01-23
JPS59141559A (en) 1984-08-14
EP0115472A3 (en) 1985-10-02
PT78007B (en) 1986-06-18
ZA84560B (en) 1984-09-26
DK35884A (en) 1984-07-28
NO840310L (en) 1984-07-30
GR81746B (en) 1984-12-12
KR840007571A (en) 1984-12-08
EP0115472A2 (en) 1984-08-08
DK35884D0 (en) 1984-01-26
PT78007A (en) 1984-02-01
DD216005A5 (en) 1984-11-28
AU2383884A (en) 1984-08-02

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