ZA842240B - A procedure for the photometric determination of the activated partial thromboplastin time and a reagent for this purpose - Google Patents
A procedure for the photometric determination of the activated partial thromboplastin time and a reagent for this purposeInfo
- Publication number
 - ZA842240B ZA842240B ZA842240A ZA842240A ZA842240B ZA 842240 B ZA842240 B ZA 842240B ZA 842240 A ZA842240 A ZA 842240A ZA 842240 A ZA842240 A ZA 842240A ZA 842240 B ZA842240 B ZA 842240B
 - Authority
 - ZA
 - South Africa
 - Prior art keywords
 - reagent
 - procedure
 - partial thromboplastin
 - thromboplastin time
 - activated partial
 - Prior art date
 
Links
- PGOHTUIFYSHAQG-LJSDBVFPSA-N (2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]-5-oxopentanoyl]amino]hexanoic acid Chemical compound CSCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(O)=O PGOHTUIFYSHAQG-LJSDBVFPSA-N 0.000 title 1
 - 102000002262 Thromboplastin Human genes 0.000 title 1
 - 108010000499 Thromboplastin Proteins 0.000 title 1
 - 239000003153 chemical reaction reagent Substances 0.000 title 1
 - 239000003593 chromogenic compound Substances 0.000 abstract 1
 
Classifications
- 
        
- G—PHYSICS
 - G01—MEASURING; TESTING
 - G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
 - G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
 - G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
 - G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
 - G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
 
 - 
        
- C—CHEMISTRY; METALLURGY
 - C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
 - C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
 - C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
 - C12Q2337/10—Anilides
 - C12Q2337/12—Para-Nitroanilides p-NA
 
 
Landscapes
- Health & Medical Sciences (AREA)
 - Life Sciences & Earth Sciences (AREA)
 - Hematology (AREA)
 - Engineering & Computer Science (AREA)
 - Molecular Biology (AREA)
 - Biomedical Technology (AREA)
 - Chemical & Material Sciences (AREA)
 - Immunology (AREA)
 - Urology & Nephrology (AREA)
 - Physics & Mathematics (AREA)
 - General Physics & Mathematics (AREA)
 - Cell Biology (AREA)
 - Food Science & Technology (AREA)
 - Medicinal Chemistry (AREA)
 - Biotechnology (AREA)
 - Analytical Chemistry (AREA)
 - Biochemistry (AREA)
 - General Health & Medical Sciences (AREA)
 - Microbiology (AREA)
 - Pathology (AREA)
 - Investigating Or Analysing Biological Materials (AREA)
 - Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
 - Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
 - Automatic Analysis And Handling Materials Therefor (AREA)
 - Peptides Or Proteins (AREA)
 - Cephalosporin Compounds (AREA)
 - Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
 - Medicines Containing Material From Animals Or Micro-Organisms (AREA)
 
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| DE19833311287 DE3311287A1 (de) | 1983-03-28 | 1983-03-28 | Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu | 
Publications (1)
| Publication Number | Publication Date | 
|---|---|
| ZA842240B true ZA842240B (en) | 1984-10-31 | 
Family
ID=6194903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| ZA842240A ZA842240B (en) | 1983-03-28 | 1984-03-27 | A procedure for the photometric determination of the activated partial thromboplastin time and a reagent for this purpose | 
Country Status (14)
| Country | Link | 
|---|---|
| EP (1) | EP0123883B1 (enEXAMPLES) | 
| JP (1) | JPS59187800A (enEXAMPLES) | 
| AT (1) | ATE67520T1 (enEXAMPLES) | 
| AU (1) | AU582534B2 (enEXAMPLES) | 
| CA (1) | CA1250213A (enEXAMPLES) | 
| DE (2) | DE3311287A1 (enEXAMPLES) | 
| DK (1) | DK162179C (enEXAMPLES) | 
| ES (1) | ES8505115A1 (enEXAMPLES) | 
| GR (1) | GR81852B (enEXAMPLES) | 
| IE (1) | IE58463B1 (enEXAMPLES) | 
| IL (1) | IL71370A (enEXAMPLES) | 
| NO (1) | NO164443C (enEXAMPLES) | 
| NZ (1) | NZ207626A (enEXAMPLES) | 
| ZA (1) | ZA842240B (enEXAMPLES) | 
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| AU4158785A (en) * | 1984-03-26 | 1985-11-01 | International Health Services | A method of determining the clotting time of blood and particulate reagents therefor | 
| GB8426004D0 (en) * | 1984-10-15 | 1984-11-21 | Ortho Diagnostic Systems Inc | Coagulation monitoring | 
| DE3504405A1 (de) * | 1985-02-08 | 1986-08-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Bestimmung von prokallikrein | 
| SE8702556D0 (sv) * | 1987-06-18 | 1987-06-18 | Kabivitrum Ab | Bestemning av vid proteolys aktiva komponenter | 
| US4865984A (en) * | 1988-02-08 | 1989-09-12 | Mount Sinai School Of Medicine Of The City University Of New York | Dynamic continuous flow enzyme reactor | 
| DE4006634A1 (de) * | 1990-03-03 | 1991-09-05 | Behringwerke Ag | Funktioneller test zur bestimmung der protein s-aktivitaet | 
| JP3180824B2 (ja) * | 1991-08-30 | 2001-06-25 | シスメックス株式会社 | 血液凝固試薬 | 
| DK0570356T3 (da) * | 1992-05-15 | 1999-09-20 | Immuno Ag | Reagens til bestemmelse af den aktiverede partielle thromboplastintid (APTT) | 
| AT402074B (de) * | 1993-04-30 | 1997-01-27 | Immuno Ag | Reagens zur bestimmung der aptt | 
| AT398983B (de) * | 1992-05-15 | 1995-02-27 | Immuno Ag | Reagens zur bestimmung der aptt | 
| ATE177536T1 (de) * | 1993-06-30 | 1999-03-15 | Diagnostische Forsch Stiftung | Messung des aktivierten partiellen thromboplastinzeit (aptt) in einer einstufen- reaktion | 
| US5780255A (en) * | 1995-06-09 | 1998-07-14 | Instrumentation Laboratory, S.P.A. | Protein C pathway screening test | 
| US6699718B1 (en) | 1999-09-03 | 2004-03-02 | Roche Diagnostics Corporation | Method, reagent and test cartridge for determining clotting time | 
| US6448024B1 (en) | 2000-10-03 | 2002-09-10 | Roche Diagnostics Corporation | Method, reagent, cartridge, and device for determining fibrinogen | 
| DE60227163D1 (de) | 2001-05-09 | 2008-07-31 | Axis Shield Asa | Testvorrichtung | 
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| US3486981A (en) * | 1965-03-15 | 1969-12-30 | Roy E Speck | Substances relating to testing of blood-coagulation | 
| DE2915310A1 (de) * | 1979-04-14 | 1980-10-30 | Behringwerke Ag | Neues partielles thromboplastin und dessen verwendung | 
| CA1161432A (en) * | 1980-02-12 | 1984-01-31 | Lars G. Svendsen | Tripeptide derivatives and their application in assaying enzymes | 
| DE3244030A1 (de) * | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung | 
| US4487060A (en) * | 1983-05-18 | 1984-12-11 | Glenayre Electronis, Ltd. | Railway brake pressure monitor | 
- 
        1983
        
- 1983-03-28 DE DE19833311287 patent/DE3311287A1/de not_active Withdrawn
 
 - 
        1984
        
- 1984-02-27 DK DK109084A patent/DK162179C/da active
 - 1984-03-22 DE DE8484103163T patent/DE3485067D1/de not_active Expired - Lifetime
 - 1984-03-22 AT AT84103163T patent/ATE67520T1/de not_active IP Right Cessation
 - 1984-03-22 EP EP84103163A patent/EP0123883B1/de not_active Expired - Lifetime
 - 1984-03-26 NZ NZ207626A patent/NZ207626A/en unknown
 - 1984-03-26 GR GR74205A patent/GR81852B/el unknown
 - 1984-03-26 ES ES530983A patent/ES8505115A1/es not_active Expired
 - 1984-03-27 ZA ZA842240A patent/ZA842240B/xx unknown
 - 1984-03-27 AU AU26211/84A patent/AU582534B2/en not_active Ceased
 - 1984-03-27 JP JP59057507A patent/JPS59187800A/ja active Granted
 - 1984-03-27 IL IL71370A patent/IL71370A/xx not_active IP Right Cessation
 - 1984-03-27 IE IE74384A patent/IE58463B1/en not_active IP Right Cessation
 - 1984-03-27 CA CA000450594A patent/CA1250213A/en not_active Expired
 - 1984-03-28 NO NO841231A patent/NO164443C/no unknown
 
 
Also Published As
| Publication number | Publication date | 
|---|---|
| IL71370A (en) | 1989-06-30 | 
| JPS59187800A (ja) | 1984-10-24 | 
| EP0123883B1 (de) | 1991-09-18 | 
| DK162179B (da) | 1991-09-23 | 
| ES530983A0 (es) | 1985-05-01 | 
| DK109084A (da) | 1984-09-29 | 
| ES8505115A1 (es) | 1985-05-01 | 
| AU2621184A (en) | 1984-10-04 | 
| AU582534B2 (en) | 1989-04-06 | 
| DE3311287A1 (de) | 1984-10-04 | 
| DK162179C (da) | 1992-03-02 | 
| NO841231L (no) | 1984-10-01 | 
| GR81852B (enEXAMPLES) | 1984-12-12 | 
| JPH0365958B2 (enEXAMPLES) | 1991-10-15 | 
| IL71370A0 (en) | 1984-06-29 | 
| CA1250213A (en) | 1989-02-21 | 
| NZ207626A (en) | 1987-05-29 | 
| EP0123883A3 (en) | 1988-02-10 | 
| NO164443C (no) | 1990-10-03 | 
| EP0123883A2 (de) | 1984-11-07 | 
| IE58463B1 (en) | 1993-09-22 | 
| DE3485067D1 (de) | 1991-10-24 | 
| DK109084D0 (da) | 1984-02-27 | 
| ATE67520T1 (de) | 1991-10-15 | 
| IE840743L (en) | 1984-09-28 | 
| NO164443B (no) | 1990-06-25 | 
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