ZA838435B - 2-piperazinyl-quinazoline derivatives,their production and pharmaceutical compositions containing them - Google Patents

2-piperazinyl-quinazoline derivatives,their production and pharmaceutical compositions containing them

Info

Publication number
ZA838435B
ZA838435B ZA838435A ZA838435A ZA838435B ZA 838435 B ZA838435 B ZA 838435B ZA 838435 A ZA838435 A ZA 838435A ZA 838435 A ZA838435 A ZA 838435A ZA 838435 B ZA838435 B ZA 838435B
Authority
ZA
South Africa
Prior art keywords
piperazinyl
production
pharmaceutical compositions
compositions containing
quinazoline derivatives
Prior art date
Application number
ZA838435A
Other languages
English (en)
Inventor
Peter Neumann
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA838435B publication Critical patent/ZA838435B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA838435A 1982-11-12 1983-11-11 2-piperazinyl-quinazoline derivatives,their production and pharmaceutical compositions containing them ZA838435B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH6614/82A CH651027A5 (de) 1982-11-12 1982-11-12 Heterocyclische verbindungen, ihre herstellung und verwendung.

Publications (1)

Publication Number Publication Date
ZA838435B true ZA838435B (en) 1985-06-26

Family

ID=4312330

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838435A ZA838435B (en) 1982-11-12 1983-11-11 2-piperazinyl-quinazoline derivatives,their production and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US4588725A (xx)
JP (1) JPS59101470A (xx)
AU (1) AU576739B2 (xx)
BE (1) BE898151A (xx)
CA (1) CA1209994A (xx)
CH (1) CH651027A5 (xx)
DE (1) DE3339943A1 (xx)
DK (1) DK158514C (xx)
ES (1) ES8504774A1 (xx)
FI (1) FI79303C (xx)
FR (1) FR2536072B1 (xx)
GB (1) GB2130207B (xx)
HU (1) HU193188B (xx)
IE (1) IE56229B1 (xx)
IL (1) IL70189A (xx)
IT (1) IT1170578B (xx)
NL (1) NL8303821A (xx)
NZ (1) NZ206224A (xx)
PH (1) PH21835A (xx)
PT (1) PT77638B (xx)
SE (1) SE460668B (xx)
ZA (1) ZA838435B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0647540B2 (ja) * 1985-07-16 1994-06-22 エーザイ株式会社 虚血性心疾患・不整脈治療・予防剤
JP2561689B2 (ja) * 1986-02-24 1996-12-11 三井石油化学工業株式会社 神経疾患用治療薬
DE3752141T2 (de) * 1986-02-24 1998-03-26 Mitsui Petrochemical Ind Mittel zur behandlung von neuropathie
US4877790A (en) * 1987-12-15 1989-10-31 Kanebo Limited Quinazoline derivative, processes for its production, and cerebral dysfunction remedying agent comprising it as active ingredient
US4994460A (en) * 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
EP0538693A3 (en) * 1991-10-23 1994-08-17 Squibb & Sons Inc Stereoselective preparation of halophenyl alcohols
TW334434B (en) * 1995-05-16 1998-06-21 Kanebo Ltd Novel quinazoline compound and anti-tumor agent
CA2543710A1 (en) * 2003-11-03 2005-05-12 Warner-Lambert Company Llc Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129219C (xx) * 1965-12-16
GB1199768A (en) * 1966-10-31 1970-07-22 Pfizer & Co C Nitrogen Heterocycles and process for their preparation
US3517005A (en) * 1967-10-26 1970-06-23 Pfizer & Co C Certain 2- and 4-substituted quinazolines
GB1187680A (en) * 1967-11-15 1970-04-15 Science Union & Cie New Heterocyclic Substituted Piperazines
GB1369379A (en) * 1972-04-07 1974-10-09 Science Union & Cie Benzodioxole derivatives and processes for preparing them
GB1553436A (en) * 1976-09-17 1979-09-26 Bellon R Lab Derivatives of pipemidic acid
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
FI70411C (fi) * 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat

Also Published As

Publication number Publication date
GB2130207B (en) 1986-02-26
IT1170578B (it) 1987-06-03
FR2536072B1 (fr) 1986-10-10
FI834061A (fi) 1984-05-13
ES527164A0 (es) 1985-05-01
GB2130207A (en) 1984-05-31
NL8303821A (nl) 1984-06-01
DK514283D0 (da) 1983-11-10
FI79303C (fi) 1989-12-11
BE898151A (fr) 1984-05-04
HU193188B (en) 1987-08-28
CA1209994A (en) 1986-08-19
AU2114783A (en) 1984-05-17
AU576739B2 (en) 1988-09-08
FR2536072A1 (fr) 1984-05-18
SE460668B (sv) 1989-11-06
ES8504774A1 (es) 1985-05-01
PT77638A (en) 1983-12-01
SE8306225L (sv) 1984-05-13
PT77638B (en) 1986-03-21
IE832626L (en) 1984-05-12
IE56229B1 (en) 1991-05-22
DK514283A (da) 1984-05-13
SE8306225D0 (sv) 1983-11-11
DE3339943A1 (de) 1984-05-17
HUT34018A (en) 1985-01-28
US4588725A (en) 1986-05-13
DK158514B (da) 1990-05-28
GB8330016D0 (en) 1983-12-14
NZ206224A (en) 1986-09-10
JPS59101470A (ja) 1984-06-12
IL70189A (en) 1987-01-30
FI834061A0 (fi) 1983-11-04
PH21835A (en) 1988-03-17
FI79303B (fi) 1989-08-31
IT8349298A0 (it) 1983-11-08
CH651027A5 (de) 1985-08-30
DK158514C (da) 1990-11-05
IL70189A0 (en) 1984-02-29

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