ZA828104B - N-substituted ergoline-and 9,10 didehydroergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical compositions - Google Patents

N-substituted ergoline-and 9,10 didehydroergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical compositions

Info

Publication number
ZA828104B
ZA828104B ZA828104A ZA828104A ZA828104B ZA 828104 B ZA828104 B ZA 828104B ZA 828104 A ZA828104 A ZA 828104A ZA 828104 A ZA828104 A ZA 828104A ZA 828104 B ZA828104 B ZA 828104B
Authority
ZA
South Africa
Prior art keywords
didehydroergoline
carboxamide
production
pharmaceutical compositions
aminomethyl derivatives
Prior art date
Application number
ZA828104A
Other languages
English (en)
Inventor
Rene Ziegler
Peter Stuetz
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA828104B publication Critical patent/ZA828104B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
ZA828104A 1981-11-04 1982-11-04 N-substituted ergoline-and 9,10 didehydroergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical compositions ZA828104B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH7056/81A CH653333A5 (de) 1981-11-04 1981-11-04 N-substituierte ergolin- und 9,10-didehydroergolinderivate, ihre herstellung und sie enthaltende arzneimittel.

Publications (1)

Publication Number Publication Date
ZA828104B true ZA828104B (en) 1984-06-27

Family

ID=4319237

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA828104A ZA828104B (en) 1981-11-04 1982-11-04 N-substituted ergoline-and 9,10 didehydroergoline-8-carboxamide-and-8-aminomethyl derivatives,their production and their pharmaceutical compositions

Country Status (27)

Country Link
US (1) US4783464A (sv)
JP (1) JPS5885885A (sv)
AT (1) AT382374B (sv)
AU (1) AU561250B2 (sv)
BE (1) BE894844A (sv)
CA (1) CA1193249A (sv)
CH (1) CH653333A5 (sv)
CY (1) CY1421A (sv)
DE (1) DE3239788A1 (sv)
DK (1) DK486582A (sv)
ES (1) ES8403898A1 (sv)
FI (1) FI71735C (sv)
FR (1) FR2516084A1 (sv)
GB (1) GB2108502B (sv)
HK (1) HK37188A (sv)
HU (1) HU187798B (sv)
IE (1) IE54122B1 (sv)
IL (1) IL67156A (sv)
IT (1) IT1189409B (sv)
KE (1) KE3797A (sv)
MY (1) MY8600310A (sv)
NL (1) NL8204213A (sv)
NZ (1) NZ202363A (sv)
PH (1) PH20595A (sv)
PT (1) PT75773A (sv)
SE (1) SE450122B (sv)
ZA (1) ZA828104B (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3957785A (en) * 1971-12-02 1976-05-18 Societa' Farmaceutici Italia S.P.A. Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
BE792515A (fr) * 1971-12-10 1973-06-08 Sandoz Sa Nouveaux derives de l'acide lysergique, leur preparation et leur application comme medicaments
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
GB1555751A (en) * 1977-02-02 1979-11-14 Farmaceutici Italia Ergoline deritatives
FI76085C (sv) * 1981-07-21 1988-09-09 Erba Farmitalia Förfarande för framställning av ergolinderivat

Also Published As

Publication number Publication date
US4783464A (en) 1988-11-08
GB2108502B (en) 1985-07-10
FR2516084B1 (sv) 1985-01-11
SE8206217D0 (sv) 1982-11-02
IT1189409B (it) 1988-02-04
AT382374B (de) 1987-02-25
IL67156A0 (en) 1983-03-31
IE822627L (en) 1983-05-04
IL67156A (en) 1985-05-31
AU561250B2 (en) 1987-05-07
FI823694A0 (fi) 1982-10-28
CA1193249A (en) 1985-09-10
NZ202363A (en) 1985-12-13
FI823694L (fi) 1983-05-05
IT8249418A0 (it) 1982-11-03
FR2516084A1 (fr) 1983-05-13
GB2108502A (en) 1983-05-18
JPH0366306B2 (sv) 1991-10-16
NL8204213A (nl) 1983-06-01
FI71735B (fi) 1986-10-31
ES517082A0 (es) 1984-04-01
DE3239788A1 (de) 1983-05-11
SE450122B (sv) 1987-06-09
ES8403898A1 (es) 1984-04-01
ATA400482A (de) 1986-07-15
MY8600310A (en) 1986-12-31
JPS5885885A (ja) 1983-05-23
PT75773A (en) 1982-12-01
BE894844A (fr) 1983-04-28
HK37188A (en) 1988-05-27
AU9010782A (en) 1983-05-12
PH20595A (en) 1987-02-24
IE54122B1 (en) 1989-06-21
CY1421A (en) 1988-09-02
FI71735C (sv) 1987-02-09
DK486582A (da) 1983-05-05
HU187798B (en) 1986-02-28
CH653333A5 (de) 1985-12-31
KE3797A (en) 1988-03-11
SE8206217L (sv) 1983-05-05

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