ZA826796B - Process for the preparation of 5'ribonucleotides - Google Patents

Process for the preparation of 5'ribonucleotides

Info

Publication number
ZA826796B
ZA826796B ZA826796A ZA826796A ZA826796B ZA 826796 B ZA826796 B ZA 826796B ZA 826796 A ZA826796 A ZA 826796A ZA 826796 A ZA826796 A ZA 826796A ZA 826796 B ZA826796 B ZA 826796B
Authority
ZA
South Africa
Prior art keywords
mixture
crude
ribonucleotides
phosphodiesterase
methacrylamide
Prior art date
Application number
ZA826796A
Other languages
English (en)
Inventor
Reinhold Keller
Merten Schlingmann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA826796B publication Critical patent/ZA826796B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087Acrylic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C12N11/12Cellulose or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
ZA826796A 1981-09-17 1982-09-16 Process for the preparation of 5'ribonucleotides ZA826796B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813136940 DE3136940A1 (de) 1981-09-17 1981-09-17 "verfahren zur herstellung von 5'-ribonucleotiden"

Publications (1)

Publication Number Publication Date
ZA826796B true ZA826796B (en) 1983-07-27

Family

ID=6141916

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA826796A ZA826796B (en) 1981-09-17 1982-09-16 Process for the preparation of 5'ribonucleotides

Country Status (12)

Country Link
US (1) US4649111A (ro)
EP (1) EP0075262B1 (ro)
JP (1) JPS5867192A (ro)
KR (1) KR840001593A (ro)
AT (1) ATE24019T1 (ro)
AU (1) AU551838B2 (ro)
CA (1) CA1191102A (ro)
DE (2) DE3136940A1 (ro)
ES (1) ES8306163A1 (ro)
RO (1) RO84708B (ro)
SU (1) SU1435158A3 (ro)
ZA (1) ZA826796B (ro)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90600A0 (en) * 1988-06-16 1990-01-18 Du Pont Polynucleotide phosphorylase immobilized on epoxy-activated beads
WO1991000346A1 (en) * 1989-07-03 1991-01-10 E.I. Du Pont De Nemours And Company Polynucleotide phosphorylase immobilized on tris(hydroxymethyl)methylacrylamide polymer beads
US6277562B1 (en) * 1993-01-26 2001-08-21 Robert-A. Ollar Method for paraffinophilic isolation and identification from a body specimen
ATE431848T1 (de) * 1999-03-05 2009-06-15 Mitsubishi Rayon Co Microarray mit einer biologischen substanz
DK1587947T3 (da) * 2003-01-27 2010-05-10 Dsm Ip Assets Bv Fremstilling af 5'-ribonucleotider
WO2004078342A1 (ja) 2003-03-04 2004-09-16 Manac Inc. アニオン性置換基を有する物質の捕捉剤
AU2003902303A0 (en) * 2003-05-14 2003-05-29 Protech Research Pty Ltd Extracting and purifying enzymes
WO2008128209A1 (en) * 2007-04-12 2008-10-23 Designer Molecules, Inc. Polyfunctional epoxy oligomers
ITUA20161550A1 (it) * 2016-03-10 2017-09-10 Prosol S P A Procedimento per la produzione di RNA
EP4166665A1 (en) * 2021-10-12 2023-04-19 Prosol S.p.A. Process for the production of rna and 5'-ribonucleotides with a high degree of purity

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3139385A (en) * 1960-12-20 1964-06-30 Takeda Chemical Industries Ltd Method for the production of 5'-nucleotides
GB940660A (en) * 1961-02-04 1963-10-30 Waldhof Zellstoff Fab Improvements in and relating to the production of 5-nucleotides
DE2215539C2 (de) * 1972-03-30 1984-08-02 Bayer Ag, 5090 Leverkusen Neue wasserunlösliche Enzym-, insbesondere Penicillinacylase-oder Enzyminhibitor-Präparate
US4044196A (en) * 1972-03-30 1977-08-23 Bayer Aktiengesellschaft Crosslinked copolymers of α,β-olefinically unsaturated dicarboxylic anhydrides
FR2308636A1 (fr) * 1975-04-23 1976-11-19 Choay Sa Matrices portant simultanement plusieurs fonctions enzymatiques differentes, leur procede de production, et procede de preparation d'oligonucleotides et de polynucleotides a terminaisons specifiques, a l'aide desdites matrices
JPS5218892A (en) * 1975-08-04 1977-02-12 Kyowa Hakko Kogyo Co Ltd Process for preparing 5'-ribonucleotides
US4206243A (en) * 1976-07-27 1980-06-03 Hoechst Aktiengesellschaft Process for reducing the contents of lipids and nucleic acid in microbial cell masses
US4208309A (en) * 1977-05-20 1980-06-17 Rohm Gmbh Pearl polymer containing hollow pearls
DE2722751C2 (de) * 1977-05-20 1990-06-21 Röhm GmbH, 6100 Darmstadt Perlpolymerisat mit einem Teilchendurchmesser von 5 bis 1000 μm und innerem Hohlraum
US4342833A (en) * 1977-05-31 1982-08-03 Bethesda Research Laboratory Immobilized restriction endonucleases
DE2732301C3 (de) * 1977-07-16 1980-12-11 Roehm Gmbh, 6100 Darmstadt Verfahren zur Herstellung von stabilisierten trägergebundenen Proteinen
JPS5592672A (en) * 1979-01-05 1980-07-14 Ajinomoto Co Inc Preparation of yeast extract

Also Published As

Publication number Publication date
ES515775A0 (es) 1983-05-01
EP0075262A2 (de) 1983-03-30
KR840001593A (ko) 1984-05-07
ES8306163A1 (es) 1983-05-01
EP0075262A3 (en) 1984-10-10
SU1435158A3 (ru) 1988-10-30
AU551838B2 (en) 1986-05-15
AU8844782A (en) 1983-03-24
EP0075262B1 (de) 1986-12-03
DE3274560D1 (en) 1987-01-15
JPS5867192A (ja) 1983-04-21
RO84708A (ro) 1984-07-17
DE3136940A1 (de) 1983-03-31
ATE24019T1 (de) 1986-12-15
RO84708B (ro) 1984-09-30
CA1191102A (en) 1985-07-30
US4649111A (en) 1987-03-10

Similar Documents

Publication Publication Date Title
US4248968A (en) Process for producing acrylamide or methacrylamide utilizing microorganisms
JPS57115186A (en) Preparation of l-lysine by fermentation
ZA826796B (en) Process for the preparation of 5'ribonucleotides
JPS6221519B2 (ro)
EP0071023A3 (en) Method for producing l-isoleucine by fermentation
DE59106289D1 (de) Verfahren zur Herstellung von Salzen des L-Ornithins.
JPS55144889A (en) Continuous preparation of acrylamide or methacrylamide by microorganism
ES8206620A1 (es) Procedimiento para la produccion de proteinas y celulas con reducido contenido de acido nucleico
JPS561888A (en) Preparation of concentrated aqueous solution of acrylamide with microorganism
EP0272026A2 (en) Process for the decomposition of acrylamide
DE3576522D1 (de) Verfahren zur enzymatischen hydrolyse von d-alpha-aminosaeureamiden.
Keller et al. Process for the preparation of 5-ribonucleotides.
ATE35826T1 (de) Verfahren zur herstellung von l-alphaaminos|uren.
Chibata et al. Continuous enzyme reactions by immobilized microbial cells
JPS55108294A (en) Production of purine nucleoside through fermentation process
Camien et al. Utilization of L-, D-and DL-Forms of Asparagine and Aspartic Acid by Leuconostoc mesenteroides P-60.
FR2313394A1 (fr) Procede de preparation d'un produit doue d'activite enzymatique
JPS57163487A (en) Production of l-arginine through fermentation process
US3898127A (en) Process for preparing urocanic acid
JPS57115185A (en) Preparation of l-lysine by fermentation
GB1209711A (en) A process for production of inosine and 5'-guanylic acid nucleotides
JP2670130B2 (ja) ロドコッカス属細菌の培養方法及び該微生物を用いた2―ケト酪酸の製造方法
JPS5664796A (en) Preparation of 6-aminopenicillanic acid and 6- aminopenicillanic acid s-oxide
Razzell [32] Preparation of oligoribonucleotides with RNase I
JPS5768793A (en) Preparation of l-threonine by fermentation