ZA821449B - Novel fluoro prostacyclins - Google Patents

Novel fluoro prostacyclins

Info

Publication number
ZA821449B
ZA821449B ZA821449A ZA821449A ZA821449B ZA 821449 B ZA821449 B ZA 821449B ZA 821449 A ZA821449 A ZA 821449A ZA 821449 A ZA821449 A ZA 821449A ZA 821449 B ZA821449 B ZA 821449B
Authority
ZA
South Africa
Prior art keywords
prostacyclins
novel fluoro
fluoro
novel
fluoro prostacyclins
Prior art date
Application number
ZA821449A
Other languages
English (en)
Inventor
George William Holland
Hans Maag
Perry Rosen
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA821449B publication Critical patent/ZA821449B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA821449A 1981-03-11 1982-03-04 Novel fluoro prostacyclins ZA821449B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24281881A 1981-03-11 1981-03-11

Publications (1)

Publication Number Publication Date
ZA821449B true ZA821449B (en) 1983-01-26

Family

ID=22916307

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA821449A ZA821449B (en) 1981-03-11 1982-03-04 Novel fluoro prostacyclins

Country Status (5)

Country Link
JP (1) JPS57171988A (ko)
KR (1) KR860002049B1 (ko)
BE (1) BE892434A (ko)
GR (1) GR76075B (ko)
ZA (1) ZA821449B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation
EP0054795B1 (en) * 1980-12-09 1987-07-15 Teijin Limited Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
JPS57200378A (en) * 1981-06-02 1982-12-08 Teijin Ltd Halogenated pgi2 and its preparation
JPS58150583A (ja) * 1982-03-04 1983-09-07 Teijin Ltd 新規なハロゲン化プロスタサイクリン類、それらの製造法およびそれらを活性成分とする薬学的組成物
JPS59227888A (ja) * 1983-06-10 1984-12-21 Asahi Glass Co Ltd ７−フルオロプロスタグランジン類の製造方法
DE69531110T2 (de) * 1994-02-17 2004-05-19 Asahi Glass Co., Ltd. Difluoroprostacycline, Zwischenprodukte zu deren Herstellung und Herstellungsverfahren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU184917B (en) * 1980-10-27 1984-11-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 7-substituted pgi down 2 derivatives
JPS57165382A (en) * 1981-04-06 1982-10-12 Teijin Ltd Fluoro-pgi2 compound and its preparation

Also Published As

Publication number Publication date
KR830009079A (ko) 1983-12-17
JPS57171988A (en) 1982-10-22
BE892434A (fr) 1982-09-10
GR76075B (ko) 1984-08-03
KR860002049B1 (ko) 1986-11-20

Similar Documents

Publication Publication Date Title
GB2172287B (en) Fluoro desoxycarbohydrates
DE3276482D1 (en) Novel n-aryl-piperazinealkanamides
DE3280020D1 (en) Prostaglandins
GB2092686B (en) Transmissions
GB2093033B (en) 1a 25-dihydroxy-2 -fluorovitamin d3
GB2111504B (en) 23-dehydro-25-hydroxyvitamin d3
PH17410A (en) Novel fluoro prostacyclins
ZA821449B (en) Novel fluoro prostacyclins
DE3267651D1 (en) 5 fluoro pgi compounds
JPS57175903A (en) Object inspecter
YU166582A (en) Gearbox
ZA824428B (en) Novel n-aryl-piperazinealkanamides
GB2084991B (en) Prostacyclins
GB2092067B (en) Continuous staionery
ZA821347B (en) Novel aroylimidazole-2-ones
ZA821888B (en) Novel phenyl-piperidines
IL65605A0 (en) Halohydrins
GB2137624B (en) Novel dithiolaniminoxoimidazolidines
GB2103693B (en) Mine-roof supports
KR830000150Y1 (en) Double ballpen
ZA805862B (en) Prostacyclins
IE801964L (en) Prostacyclins
PH16125A (en) Prostacyclins
JPS57133474A (en) Encoder
CS754481A1 (en) Zpusob pripravy cis diammin dichloroplatnaneho komplexu