ZA817696B - N-substituted omega-(2-oxo-4-imidazolin-1-yl)alcanoic acids,salts and esters thereof,process for producing the same and these active agents containing pharmaceutical compounds - Google Patents

N-substituted omega-(2-oxo-4-imidazolin-1-yl)alcanoic acids,salts and esters thereof,process for producing the same and these active agents containing pharmaceutical compounds

Info

Publication number
ZA817696B
ZA817696B ZA817696A ZA817696A ZA817696B ZA 817696 B ZA817696 B ZA 817696B ZA 817696 A ZA817696 A ZA 817696A ZA 817696 A ZA817696 A ZA 817696A ZA 817696 B ZA817696 B ZA 817696B
Authority
ZA
South Africa
Prior art keywords
imidazolin
oxo
esters
salts
producing
Prior art date
Application number
ZA817696A
Other languages
English (en)
Inventor
Hans Heiner Lautenschlaeger
Hans Betzing
Brigitte Stoll
Manfred Probst
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of ZA817696B publication Critical patent/ZA817696B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA817696A 1980-11-11 1981-11-06 N-substituted omega-(2-oxo-4-imidazolin-1-yl)alcanoic acids,salts and esters thereof,process for producing the same and these active agents containing pharmaceutical compounds ZA817696B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803042466 DE3042466A1 (de) 1980-11-11 1980-11-11 N-substituierte (omega) -(2-oxo-4-imidazolin-l-yl)-alkansaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
ZA817696B true ZA817696B (en) 1982-10-27

Family

ID=6116469

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA817696A ZA817696B (en) 1980-11-11 1981-11-06 N-substituted omega-(2-oxo-4-imidazolin-1-yl)alcanoic acids,salts and esters thereof,process for producing the same and these active agents containing pharmaceutical compounds

Country Status (9)

Country Link
US (1) US4349684A (fr)
EP (1) EP0051829B1 (fr)
JP (1) JPS57108073A (fr)
AT (1) ATE10626T1 (fr)
DE (1) DE3042466A1 (fr)
DK (1) DK495781A (fr)
GR (1) GR74703B (fr)
IE (1) IE52079B1 (fr)
ZA (1) ZA817696B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3228271A1 (de) * 1982-07-29 1984-02-02 A. Nattermann & Cie GmbH, 5000 Köln Triphenylimidazolyloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3323870A1 (de) * 1983-07-02 1985-01-03 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazol-2-ylthioalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4598149A (en) * 1984-03-02 1986-07-01 Merck & Co., Inc. 3-amino-2-hydroxypropyl of pyrimidin-4-one useful as antihypertensive, cardioprotective, antiarrythmic, and antianginal agents
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.
CA2014537A1 (fr) * 1989-04-26 1990-10-26 Yoshio Hayashi Derives de 4-imidazoline
GB9019839D0 (en) * 1990-09-11 1990-10-24 Smith Kline French Lab Compounds
GB9019840D0 (en) * 1990-09-11 1990-10-24 Smith Kline French Lab Compounds
CA2085844A1 (fr) * 1991-12-27 1993-06-28 Nobuyuki Hamanaka Derives fusionnes de l'acide benzeneoxyacetique
WO1995029163A1 (fr) * 1994-04-27 1995-11-02 Nippon Soda Co., Ltd. Derive d'imidazole et procede de production de ce derive
US6017926A (en) * 1997-12-17 2000-01-25 Merck & Co., Inc. Integrin receptor antagonists
ES2243016T3 (es) * 1997-12-17 2005-11-16 MERCK & CO., INC. Antagonistas de receptores de integrinas.
JP2003510360A (ja) * 1999-10-04 2003-03-18 メルク エンド カムパニー インコーポレーテッド インテグリン受容体拮抗薬
SE0100569D0 (sv) * 2001-02-20 2001-02-20 Astrazeneca Ab New compounds
CA2618724A1 (fr) 2005-08-18 2007-02-22 Synta Pharmaceuticals Corp. Derives d'imidazole modulant l'activite de hsp90
DE102006024024A1 (de) 2006-05-23 2007-11-29 Bayer Healthcare Aktiengesellschaft Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung
DE102008060967A1 (de) 2008-12-06 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Substituierte Phenylsulfonyltriazolone und ihre Verwendung
DE102010001064A1 (de) 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
RS56312B1 (sr) 2010-02-27 2017-12-29 Bayer Ip Gmbh Ariltriazoloni spojeni sa bis-arilom i njihova upotreba
DE102010040187A1 (de) 2010-09-02 2012-03-08 Bayer Schering Pharma Aktiengesellschaft Substituierte N-Phenethyl-triazolonacetamide und ihre Verwendung
DE102010040924A1 (de) 2010-09-16 2012-03-22 Bayer Schering Pharma Aktiengesellschaft Substituierte Phenylacet- und Phenylpropanamide und ihre Verwendung
SG11201703199UA (en) 2014-11-03 2017-05-30 Bayer Pharma AG Hydroxyalkyl-substituted phenyltriazole derivatives and uses thereof
US9988367B2 (en) 2016-05-03 2018-06-05 Bayer Pharma Aktiengesellschaft Amide-substituted pyridinyltriazole derivatives and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2194369B1 (fr) * 1972-08-04 1980-04-25 Roussel Uclaf
DE2713431A1 (de) * 1977-03-26 1978-09-28 Bayer Ag Verfahren zur herstellung von diacylierten 4-imidazolinonen-2 und deren verwendung fuer cycloadditionen
DE2934746A1 (de) 1979-08-28 1981-03-19 A. Nattermann & Cie GmbH, 5000 Köln Oxoimidazolinalkansaeuren, deren salze und ester sowie verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2950478A1 (de) 1979-12-14 1981-06-19 A. Nattermann & Cie GmbH, 5000 Köln 4,5-diaryl-4-imidazolin-2-on-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
JPS57108073A (en) 1982-07-05
GR74703B (fr) 1984-07-05
DE3042466A1 (de) 1982-06-16
EP0051829A1 (fr) 1982-05-19
EP0051829B1 (fr) 1984-12-05
DK495781A (da) 1982-05-12
US4349684A (en) 1982-09-14
ATE10626T1 (de) 1984-12-15
IE52079B1 (en) 1987-06-10
IE812565L (en) 1982-05-11

Similar Documents

Publication Publication Date Title
ZA817696B (en) N-substituted omega-(2-oxo-4-imidazolin-1-yl)alcanoic acids,salts and esters thereof,process for producing the same and these active agents containing pharmaceutical compounds
GB2037745B (en) Diphenylbutyl - piperazinecarboxamides
AU565908B2 (en) 7-oxabicyclo 2.2.1 hept-2-yl-5 alkyl/alkenyl carboxylic acids
ES477695A1 (es) Un procedimiento para preparar derivados de deshidrociclici-minoacidos.
PT77125A (en) Process for preparing triphenylimidazolyloxy-alkanoic acids and their derivatives and of pharmaceutical compositions containing these compounds
ES517637A0 (es) Un procedimiento de preparacion de los acidos(oxo-4-4h-(1)-benzopiran-8-il)-alcanoicos.
ZW14482A1 (en) Pyrrolidine derivates
IE830607L (en) Imidazolylphenylpyridazinones
GR861169B (en) Method for preparing n-(quinolyl) glycinamide derivatives and their application as psychotropes
ZA817698B (en) N-benzoyl-omega-anilino alkane carboxylic acids,salts and esters thereof,process for producing the same and pharmaceutical preparations containing the same
SE8005712L (sv) Polyprenylkarboxylsyraamider, forfarande for deras framstellning samt farmaceutiska kompositioner innehallande dessa foreningar
DE3270446D1 (en) Diamides of substituted hydroxymalonic acids, process for their preparation and their use as pesticides
GR3003656T3 (fr)
DE3463143D1 (en) 1-0-alkyl-3-amino-propan-1.2-diol-2-0-phospholipids, process for producing the same and pharmaceutical preparations containing the same
ES8407021A1 (es) Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico.
SE7906681L (sv) Ftalazonderivat
PT77285B (en) Process for preparing substituted benzenosulphonates and pharmaceutical compositions containing the same
ES2062214T3 (es) Derivados de aminooligohidroxi inhibidores de renina.
DE3469527D1 (en) Nortropine derivative, process for its preparation and its use
IN170286B (fr)
SE8204791D0 (sv) Process for preparing alkoxy-vincaminic acid esters and alkoxy-apovincaminic acid esters
IL71430A (en) 2-imino-n-phenylsulfonyl-imidazolidine derivatives,process for the manufacture thereof and pharmaceutical preparations containing such compounds
SE7907656L (sv) 3,4-dihydroxikanelaldehydderivat