ZA816516B - 7-oxoprostacyclin derivatives and process for the preparation thereof - Google Patents

7-oxoprostacyclin derivatives and process for the preparation thereof

Info

Publication number
ZA816516B
ZA816516B ZA816516A ZA816516A ZA816516B ZA 816516 B ZA816516 B ZA 816516B ZA 816516 A ZA816516 A ZA 816516A ZA 816516 A ZA816516 A ZA 816516A ZA 816516 B ZA816516 B ZA 816516B
Authority
ZA
South Africa
Prior art keywords
preparation
oxoprostacyclin
derivatives
oxoprostacyclin derivatives
Prior art date
Application number
ZA816516A
Other languages
English (en)
Inventor
Robert C Nickolson
Helmut Vorbrueggen
Stenzel Jorge Casals
Gerda Mannesmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA816516B publication Critical patent/ZA816516B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/07Preparation of halogenated hydrocarbons by addition of hydrogen halides
    • C07C17/08Preparation of halogenated hydrocarbons by addition of hydrogen halides to unsaturated hydrocarbons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13Dicarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4015Esters of acyclic unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/535Organo-phosphoranes
    • C07F9/5352Phosphoranes containing the structure P=C-

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA816516A 1980-09-18 1981-09-18 7-oxoprostacyclin derivatives and process for the preparation thereof ZA816516B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803035454 DE3035454A1 (de) 1980-09-18 1980-09-18 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA816516B true ZA816516B (en) 1982-09-29

Family

ID=6112413

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA816516A ZA816516B (en) 1980-09-18 1981-09-18 7-oxoprostacyclin derivatives and process for the preparation thereof

Country Status (17)

Country Link
US (1) US4466969A (fr)
EP (1) EP0059756B1 (fr)
JP (1) JPH0314031B2 (fr)
AU (1) AU557398B2 (fr)
BE (1) BE890390A (fr)
CA (1) CA1220470A (fr)
CS (1) CS226440B2 (fr)
DE (2) DE3035454A1 (fr)
DK (1) DK220982A (fr)
ES (1) ES505576A0 (fr)
FI (1) FI66367C (fr)
GR (1) GR75350B (fr)
HU (1) HU200601B (fr)
IE (1) IE51792B1 (fr)
IT (1) IT1167504B (fr)
WO (1) WO1982001002A1 (fr)
ZA (1) ZA816516B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3340988A1 (de) * 1983-11-10 1985-05-23 Schering AG, 1000 Berlin und 4709 Bergkamen 20-alkyl-7-oxoprostacyclinderivate und verfahren zu ihrer herstellung
US5190973A (en) * 1983-11-10 1993-03-02 Schering Aktiengesellschaft 20-alkyl-7-oxoprostacyclin derivatives useful as pharmaceuticals
HU191264B (en) * 1984-01-13 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect
HU197733B (en) * 1985-05-29 1989-05-29 Chinoin Gyogyszer Es Vegyeszet Process for producing ephedrin-salts of 7-oxo-prosta-cyclin derivatives
DE3610556A1 (de) * 1986-03-26 1987-10-01 Schering Ag 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU182012B (en) * 1979-11-12 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6-substituted-7-oxo-pgi down 1 derivatives
US4330553A (en) * 1979-11-12 1982-05-18 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same

Also Published As

Publication number Publication date
CA1220470A (fr) 1987-04-14
IT8124030A0 (it) 1981-09-18
FI821707A (fi) 1982-05-14
ES8205787A1 (es) 1982-08-16
US4466969A (en) 1984-08-21
FI66367B (fi) 1984-06-29
HU200601B (en) 1990-07-28
ES505576A0 (es) 1982-08-16
DK220982A (da) 1982-05-17
CS226440B2 (en) 1984-03-19
JPH0314031B2 (fr) 1991-02-25
AU557398B2 (en) 1986-12-18
IT1167504B (it) 1987-05-13
FI66367C (fi) 1984-10-10
JPS57501482A (fr) 1982-08-19
EP0059756B1 (fr) 1985-08-28
BE890390A (fr) 1982-03-17
AU7809181A (en) 1982-04-14
DE3035454A1 (de) 1982-04-22
GR75350B (fr) 1984-07-13
FI821707A0 (fi) 1982-05-14
IE51792B1 (en) 1987-04-01
DE3172032D1 (en) 1985-10-03
IE812163L (en) 1982-03-18
WO1982001002A1 (fr) 1982-04-01
EP0059756A1 (fr) 1982-09-15

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