ZA816516B - 7-oxoprostacyclin derivatives and process for the preparation thereof - Google Patents
7-oxoprostacyclin derivatives and process for the preparation thereofInfo
- Publication number
- ZA816516B ZA816516B ZA816516A ZA816516A ZA816516B ZA 816516 B ZA816516 B ZA 816516B ZA 816516 A ZA816516 A ZA 816516A ZA 816516 A ZA816516 A ZA 816516A ZA 816516 B ZA816516 B ZA 816516B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- oxoprostacyclin
- derivatives
- oxoprostacyclin derivatives
- Prior art date
Links
- ZHIHHYNLWRXTTN-GJUFTPBXSA-N (5z)-5-[(3ar,4r,5r,6as)-5-hydroxy-4-[(e,3s)-3-hydroxyoct-1-enyl]-3-oxo-4,5,6,6a-tetrahydro-3ah-cyclopenta[b]furan-2-ylidene]pentanoic acid Chemical class O1\C(=C/CCCC(O)=O)C(=O)[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 ZHIHHYNLWRXTTN-GJUFTPBXSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/07—Preparation of halogenated hydrocarbons by addition of hydrogen halides
- C07C17/08—Preparation of halogenated hydrocarbons by addition of hydrogen halides to unsaturated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4015—Esters of acyclic unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
- C07F9/5352—Phosphoranes containing the structure P=C-
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803035454 DE3035454A1 (de) | 1980-09-18 | 1980-09-18 | 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA816516B true ZA816516B (en) | 1982-09-29 |
Family
ID=6112413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA816516A ZA816516B (en) | 1980-09-18 | 1981-09-18 | 7-oxoprostacyclin derivatives and process for the preparation thereof |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4466969A (es) |
| EP (1) | EP0059756B1 (es) |
| JP (1) | JPH0314031B2 (es) |
| AU (1) | AU557398B2 (es) |
| BE (1) | BE890390A (es) |
| CA (1) | CA1220470A (es) |
| CS (1) | CS226440B2 (es) |
| DE (2) | DE3035454A1 (es) |
| DK (1) | DK220982A (es) |
| ES (1) | ES8205787A1 (es) |
| FI (1) | FI66367C (es) |
| GR (1) | GR75350B (es) |
| HU (1) | HU200601B (es) |
| IE (1) | IE51792B1 (es) |
| IT (1) | IT1167504B (es) |
| WO (1) | WO1982001002A1 (es) |
| ZA (1) | ZA816516B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3340988A1 (de) * | 1983-11-10 | 1985-05-23 | Schering AG, 1000 Berlin und 4709 Bergkamen | 20-alkyl-7-oxoprostacyclinderivate und verfahren zu ihrer herstellung |
| US5190973A (en) * | 1983-11-10 | 1993-03-02 | Schering Aktiengesellschaft | 20-alkyl-7-oxoprostacyclin derivatives useful as pharmaceuticals |
| HU191264B (en) * | 1984-01-13 | 1987-01-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect |
| HU197733B (en) * | 1985-05-29 | 1989-05-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing ephedrin-salts of 7-oxo-prosta-cyclin derivatives |
| DE3610556A1 (de) * | 1986-03-26 | 1987-10-01 | Schering Ag | 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4330553A (en) * | 1979-11-12 | 1982-05-18 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same |
| HU182012B (en) * | 1979-11-12 | 1983-12-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing 6-substituted-7-oxo-pgi down 1 derivatives |
-
1980
- 1980-09-18 DE DE19803035454 patent/DE3035454A1/de not_active Withdrawn
-
1981
- 1981-09-16 CA CA000386074A patent/CA1220470A/en not_active Expired
- 1981-09-16 GR GR66067A patent/GR75350B/el unknown
- 1981-09-17 JP JP56503683A patent/JPH0314031B2/ja not_active Expired - Lifetime
- 1981-09-17 DE DE8181903255T patent/DE3172032D1/de not_active Expired
- 1981-09-17 AU AU78091/81A patent/AU557398B2/en not_active Ceased
- 1981-09-17 US US06/385,414 patent/US4466969A/en not_active Expired - Fee Related
- 1981-09-17 EP EP81903255A patent/EP0059756B1/en not_active Expired
- 1981-09-17 CS CS816866A patent/CS226440B2/cs unknown
- 1981-09-17 ES ES505576A patent/ES8205787A1/es not_active Expired
- 1981-09-17 IE IE2163/81A patent/IE51792B1/en unknown
- 1981-09-17 BE BE0/205991A patent/BE890390A/fr not_active IP Right Cessation
- 1981-09-17 HU HU813835A patent/HU200601B/hu not_active IP Right Cessation
- 1981-09-17 WO PCT/EP1981/000148 patent/WO1982001002A1/en active IP Right Grant
- 1981-09-18 IT IT24030/81A patent/IT1167504B/it active
- 1981-09-18 ZA ZA816516A patent/ZA816516B/xx unknown
-
1982
- 1982-05-14 FI FI821707A patent/FI66367C/fi not_active IP Right Cessation
- 1982-05-17 DK DK220982A patent/DK220982A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0314031B2 (es) | 1991-02-25 |
| GR75350B (es) | 1984-07-13 |
| FI821707A0 (fi) | 1982-05-14 |
| IT1167504B (it) | 1987-05-13 |
| CA1220470A (en) | 1987-04-14 |
| IE812163L (en) | 1982-03-18 |
| IT8124030A0 (it) | 1981-09-18 |
| ES505576A0 (es) | 1982-08-16 |
| EP0059756B1 (en) | 1985-08-28 |
| DE3035454A1 (de) | 1982-04-22 |
| JPS57501482A (es) | 1982-08-19 |
| ES8205787A1 (es) | 1982-08-16 |
| AU557398B2 (en) | 1986-12-18 |
| FI821707A (fi) | 1982-05-14 |
| FI66367C (fi) | 1984-10-10 |
| AU7809181A (en) | 1982-04-14 |
| BE890390A (fr) | 1982-03-17 |
| IE51792B1 (en) | 1987-04-01 |
| DK220982A (da) | 1982-05-17 |
| WO1982001002A1 (en) | 1982-04-01 |
| CS226440B2 (en) | 1984-03-19 |
| FI66367B (fi) | 1984-06-29 |
| HU200601B (en) | 1990-07-28 |
| DE3172032D1 (en) | 1985-10-03 |
| US4466969A (en) | 1984-08-21 |
| EP0059756A1 (en) | 1982-09-15 |
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