ZA815043B - Diazepine derivatives,process for their preparation,and pharmaceutical compositions thereof - Google Patents

Diazepine derivatives,process for their preparation,and pharmaceutical compositions thereof

Info

Publication number
ZA815043B
ZA815043B ZA815043A ZA815043A ZA815043B ZA 815043 B ZA815043 B ZA 815043B ZA 815043 A ZA815043 A ZA 815043A ZA 815043 A ZA815043 A ZA 815043A ZA 815043 B ZA815043 B ZA 815043B
Authority
ZA
South Africa
Prior art keywords
piperidino
preparation
pharmaceutical compositions
hydrogen
diazepine derivatives
Prior art date
Application number
ZA815043A
Other languages
English (en)
Inventor
Guenther Schmidt
Mario Bergamaschi
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA815043B publication Critical patent/ZA815043B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Hydrogenated Pyridines (AREA)
  • Photoreceptors In Electrophotography (AREA)
ZA815043A 1980-07-24 1981-07-23 Diazepine derivatives,process for their preparation,and pharmaceutical compositions thereof ZA815043B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803028001 DE3028001A1 (de) 1980-07-24 1980-07-24 Neue, in 5-stellung substituierte 5,10-dihydro-11h-dibenzo (b,e)(1,4) diazepin-11-one, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA815043B true ZA815043B (en) 1983-03-30

Family

ID=6107969

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA815043A ZA815043B (en) 1980-07-24 1981-07-23 Diazepine derivatives,process for their preparation,and pharmaceutical compositions thereof

Country Status (21)

Country Link
US (1) US4377576A (el)
EP (1) EP0044989B1 (el)
JP (1) JPS5756470A (el)
AT (1) ATE3548T1 (el)
AU (1) AU543677B2 (el)
CA (1) CA1154763A (el)
DD (1) DD202023A5 (el)
DE (2) DE3028001A1 (el)
DK (1) DK326481A (el)
ES (1) ES504206A0 (el)
FI (1) FI67697C (el)
GB (1) GB2081264B (el)
GR (1) GR75281B (el)
HU (1) HU187340B (el)
IL (1) IL63381A0 (el)
NO (1) NO812529L (el)
NZ (1) NZ197809A (el)
PH (1) PH16815A (el)
PT (1) PT73402B (el)
YU (1) YU182581A (el)
ZA (1) ZA815043B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3204157A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte dibenzodiazepinone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3204158A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach "substituierte dibenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel"
DE3204403A1 (de) 1982-02-09 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
IT1212743B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
DD236731B3 (de) * 1983-10-19 1992-12-10 Dresden Arzneimittel Verfahren zur herstellung von neuen in 5-stellung substituierten 5,10-dihydro-11h-dibenzo|b,e¨|1,4¨diazepin-11-onen
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3531682A1 (de) * 1985-09-05 1987-03-12 Thomae Gmbh Dr K (+)-6-chlor-5,10-dihydro-5-((1-methyl-4- piperidinyl)acetyl)-11h-dibenzo(b,e)(1,4) diazepin-11-on, seine isolierung und verwendung als arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DD293582A5 (de) * 1989-07-31 1991-09-05 Arzneimittelwerk Dresden,De Neue 5-(omega-aminoacyl)-5,10-dihydro-11h-dibenzo/b,e//1,4/-diazepin-11-one, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US6297027B1 (en) 1996-07-31 2001-10-02 Purina Mills, Inc. Bovine leptin protein, nucleic acid sequences coding therefor and uses thereof
US6277592B1 (en) 1996-07-31 2001-08-21 Purina Mills, Inc. Porcine leptin protein, nucleic acid sequences coding therefor and uses thereof
WO2007056388A2 (en) * 2005-11-07 2007-05-18 The General Hospital Corporation Compositions and methods for modulating poly (adp-ribose) polymerase activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1931487C3 (de) * 1969-06-20 1975-12-18 Dr. Karl Thomae Gmbh, 7950 Biberach In 5-Stellung substituierte 5,10-Dihydro-11H-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11 -one und Verfahren zu ihrer Herstellung
DE1795176C3 (de) * 1968-08-20 1974-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung
FI49509C (fi) * 1968-08-20 1975-07-10 Thomae Gmbh Dr K Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi.

Also Published As

Publication number Publication date
ES8301224A1 (es) 1982-11-16
NO812529L (no) 1982-01-25
PH16815A (en) 1984-03-06
US4377576A (en) 1983-03-22
FI812321L (fi) 1982-01-25
DD202023A5 (de) 1983-08-24
DE3028001A1 (de) 1982-02-18
ATE3548T1 (de) 1983-06-15
HU187340B (en) 1985-12-28
IL63381A0 (en) 1981-10-30
GB2081264B (en) 1984-01-25
NZ197809A (en) 1983-06-14
PT73402B (de) 1983-06-15
ES504206A0 (es) 1982-11-16
FI67697C (fi) 1985-05-10
DK326481A (da) 1982-01-25
DE3160360D1 (en) 1983-07-07
CA1154763A (en) 1983-10-04
FI67697B (fi) 1985-01-31
GB2081264A (en) 1982-02-17
AU7337081A (en) 1982-01-28
AU543677B2 (en) 1985-04-26
PT73402A (de) 1981-08-01
GR75281B (el) 1984-07-13
EP0044989B1 (de) 1983-05-25
YU182581A (en) 1984-02-29
EP0044989A1 (de) 1982-02-03
JPS5756470A (en) 1982-04-05

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