ZA814845B - Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor - Google Patents

Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor

Info

Publication number
ZA814845B
ZA814845B ZA814845A ZA814845A ZA814845B ZA 814845 B ZA814845 B ZA 814845B ZA 814845 A ZA814845 A ZA 814845A ZA 814845 A ZA814845 A ZA 814845A ZA 814845 B ZA814845 B ZA 814845B
Authority
ZA
South Africa
Prior art keywords
group
compounds
salts
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA814845A
Other languages
English (en)
Inventor
G Phillipps
C Williamson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA814845B publication Critical patent/ZA814845B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA814845A 1980-07-15 1981-07-15 Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor ZA814845B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8023063 1980-07-15

Publications (1)

Publication Number Publication Date
ZA814845B true ZA814845B (en) 1983-02-23

Family

ID=10514771

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA814845A ZA814845B (en) 1980-07-15 1981-07-15 Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor

Country Status (12)

Country Link
US (1) US4636509A (fr)
EP (1) EP0044704B1 (fr)
JP (1) JPS5740471A (fr)
AT (1) ATE19627T1 (fr)
AU (1) AU7300381A (fr)
CA (1) CA1160226A (fr)
DE (1) DE3174554D1 (fr)
DK (1) DK315281A (fr)
ES (2) ES8301473A1 (fr)
NO (1) NO812431L (fr)
NZ (1) NZ197714A (fr)
ZA (1) ZA814845B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8403879A1 (es) * 1982-02-24 1984-04-01 Nyegaard & Co As Un procedimiento para la preparacion de pirimidin-2-onas sustituidas.
GB2135992B (en) * 1983-01-11 1986-09-24 Nyegaard & Co As Substituted pyrimidines and processes for their preparation
GB8420610D0 (en) * 1984-08-14 1984-09-19 Glaxo Group Ltd Chemical compounds
US4853388A (en) * 1987-05-15 1989-08-01 Pearlman Dale L Method for treating psoriasis with cytotoxic agents
US4849426A (en) * 1987-05-15 1989-07-18 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents
US4820711A (en) * 1987-05-15 1989-04-11 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents
US4855466A (en) * 1987-12-28 1989-08-08 E. R. Squibb & Sons, Inc. Purinyl cyclobutanes
AU707748B2 (en) * 1994-03-25 1999-07-22 Isotechnika Inc. Enhancement of the efficacy of drugs by deuteration
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
EP1752452A4 (fr) * 2004-06-04 2010-07-14 Astellas Pharma Inc Dérivé de propane-1,de 3-dione ou son sel
KR101046039B1 (ko) * 2005-03-31 2011-07-01 아스텔라스세이야쿠 가부시키가이샤 프로판-1,3-디온 유도체 또는 그의 염

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
ES8205399A1 (es) * 1980-01-07 1982-06-01 Nyegaard & Co As Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
GB2080301B (en) * 1980-07-15 1984-04-18 Glaxo Group Ltd Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them
GB2080300B (en) * 1980-07-15 1984-04-26 Glaxo Group Ltd Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DK315281A (da) 1982-01-16
AU7300381A (en) 1982-01-21
JPS5740471A (en) 1982-03-06
ES513177A0 (es) 1983-07-01
NO812431L (no) 1982-01-18
DE3174554D1 (en) 1986-06-12
ES503984A0 (es) 1982-12-01
CA1160226A (fr) 1984-01-10
ES8307758A1 (es) 1983-07-01
EP0044704B1 (fr) 1986-05-07
ES8301473A1 (es) 1982-12-01
NZ197714A (en) 1984-11-09
EP0044704A1 (fr) 1982-01-27
ATE19627T1 (de) 1986-05-15
US4636509A (en) 1987-01-13

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