ZA814216B - Porous inorganic support material coated with an organic stationary phase for use in chromatography and process for its preparation - Google Patents

Porous inorganic support material coated with an organic stationary phase for use in chromatography and process for its preparation

Info

Publication number
ZA814216B
ZA814216B ZA814216A ZA814216A ZA814216B ZA 814216 B ZA814216 B ZA 814216B ZA 814216 A ZA814216 A ZA 814216A ZA 814216 A ZA814216 A ZA 814216A ZA 814216 B ZA814216 B ZA 814216B
Authority
ZA
South Africa
Prior art keywords
chromatography
stationary phase
support material
preparation
material coated
Prior art date
Application number
ZA814216A
Other languages
English (en)
Inventor
J Schutijser
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA814216B publication Critical patent/ZA814216B/xx

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B01J20/267—Cross-linked polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28057—Surface area, e.g. B.E.T specific surface area
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/3092—Packing of a container, e.g. packing a cartridge or column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • B01J20/3263—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. an heterocyclic or heteroaromatic structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3276—Copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F292/00—Macromolecular compounds obtained by polymerising monomers on to inorganic materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995—Silane, siloxane or silicone coating
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31652—Of asbestos
    • Y10T428/31663—As siloxane, silicone or silane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Graft Or Block Polymers (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Polymerisation Methods In General (AREA)
  • Ceramic Products (AREA)
  • Laminated Bodies (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
ZA814216A 1980-06-27 1981-06-22 Porous inorganic support material coated with an organic stationary phase for use in chromatography and process for its preparation ZA814216B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8003727 1980-06-27

Publications (1)

Publication Number Publication Date
ZA814216B true ZA814216B (en) 1982-07-28

Family

ID=19835525

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA814216A ZA814216B (en) 1980-06-27 1981-06-22 Porous inorganic support material coated with an organic stationary phase for use in chromatography and process for its preparation

Country Status (13)

Country Link
US (1) US4415631A (xx)
EP (1) EP0043159B1 (xx)
JP (1) JPS5738937A (xx)
AT (1) ATE15378T1 (xx)
AU (1) AU548877B2 (xx)
CA (1) CA1170643A (xx)
DE (1) DE3172131D1 (xx)
DK (1) DK153406C (xx)
ES (1) ES8303463A1 (xx)
FI (1) FI68636C (xx)
GR (1) GR74357B (xx)
IE (1) IE51337B1 (xx)
ZA (1) ZA814216B (xx)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58202043A (ja) * 1982-05-19 1983-11-25 Sumitomo Chem Co Ltd グラフトしたクロマトグラフ充填剤およびそれを用いる鏡像体混合物の分析法
US4560704A (en) * 1982-11-12 1985-12-24 Purdue Research Foundation Polyamine based bonded phase chromatography
JPS59193141A (ja) * 1983-04-18 1984-11-01 Asahi Chem Ind Co Ltd 新規複合体とその製法
DE3328348A1 (de) * 1983-08-05 1985-02-14 Degussa Ag, 6000 Frankfurt Verfahren zur duennschichtchromatographischen trennung von enantiomeren
EP0143369B2 (en) * 1983-11-25 1997-09-24 Asahi Kasei Kogyo Kabushiki Kaisha A porous adsorbent for adsorbing low density lipoproteins
US4724207A (en) * 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
CA1253129A (en) * 1984-02-09 1989-04-25 Thomas R. Jones Porous inorganic materials
US4523997A (en) * 1984-03-02 1985-06-18 J. T. Baker Chemical Company Affinity chromatography matrix with built-in reaction indicator
US4782040A (en) * 1984-04-09 1988-11-01 Dow Corning Corporation Porous materials having a dual surface
US4600646A (en) * 1984-08-15 1986-07-15 E. I. Du Pont De Nemours And Company Metal oxide stabilized chromatography packings
JPS61210956A (ja) * 1985-03-15 1986-09-19 Cosmo Co Ltd クロマトグラフイ−用薄層棒
JPS6210005A (ja) * 1985-07-08 1987-01-19 Nippon Shiken Kogyo Kk 抗歯髄等組織刺激性及び抗為害性組成物
US4793920A (en) * 1985-12-11 1988-12-27 Lee Scientific, Inc. Chromatography columns with cast porous plugs and methods of fabricating same
US4927749A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Reagent for cell separation
US4927750A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Cell separation process
DE3619303A1 (de) * 1986-06-07 1987-12-10 Merck Patent Gmbh Optisch aktive adsorbentien
JP2504005B2 (ja) * 1986-11-17 1996-06-05 東ソー株式会社 充填剤およびその製法
US5000848A (en) * 1987-01-28 1991-03-19 Membrex, Inc. Rotary filtration device with hyperphilic membrane
US4906379A (en) * 1987-01-28 1990-03-06 Membrex, Inc. Hydrophilic article and method of producing same
CA1339812C (en) * 1988-02-19 1998-04-14 Tamami Koyama Filler for measuring enzyme activity, column packed with the filler, andmethod of measuring enzyme activity by using the column
US4919804A (en) * 1988-03-01 1990-04-24 University Of Florida Ultrasound driven synthesis of reversed and normal phase stationary phases for liquid chromatography
DE3811042A1 (de) * 1988-03-31 1989-10-19 Merck Patent Gmbh Ionenaustauscher
IL87004A (en) * 1988-07-06 1992-08-18 Technion Res & Dev Foundation Method and apparatus for bioaffinity separation
CA1327023C (en) * 1988-07-27 1994-02-15 Leonard T. Hodgins Rotary filtration device with hyperphilic membrane
US4957620A (en) * 1988-11-15 1990-09-18 Hoechst Celanese Corporation Liquid chromatography using microporous hollow fibers
US5645717A (en) * 1989-01-13 1997-07-08 Bio-Rad Laboratories, Inc. Hydrophobic polymers from water-soluble monomers and their use as chromatography media
JPH0678347B2 (ja) * 1989-01-13 1994-10-05 信越化学工業株式会社 有機けい素化合物
US5770416A (en) * 1989-05-26 1998-06-23 Upfront Chromatography A/S Permeable hollow particles having an outer shell of mechanically rigid porous material
DK259789D0 (da) * 1989-05-26 1989-05-26 Kem En Tec Ltd Aps Partikulaert materiale
US5053133A (en) * 1990-02-09 1991-10-01 Elias Klein Affinity separation with activated polyamide microporous membranes
US5211993A (en) * 1990-12-10 1993-05-18 Advanced Surface Technology, Inc. Method of making novel separation media
US5445732A (en) * 1992-06-19 1995-08-29 Sepracor Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5268097A (en) * 1992-06-19 1993-12-07 Sepracor Inc. Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same
US5906734A (en) * 1992-06-19 1999-05-25 Biosepra Inc. Passivated porous polymer supports and methods for the preparation and use of same
US5470463A (en) * 1992-06-19 1995-11-28 Sepracor Inc. Passivated porous supports and methods for the preparation and use of same
JP3583429B2 (ja) * 1993-07-16 2004-11-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 疎水クロマトグラフィーのための分離剤
DE4333674A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Nukleotidhaltiges Sorbens für die Affinitätschromatographie
DE4333821A1 (de) * 1993-10-04 1995-04-06 Merck Patent Gmbh Ionenaustauscher
DE4334353A1 (de) * 1993-10-08 1995-04-13 Merck Patent Gmbh Verfahren und Träger für die Gelpermeationschromatographie
US5374339A (en) * 1993-10-14 1994-12-20 Guillet; James E. Production of hydrogen peroxide
US5547760A (en) * 1994-04-26 1996-08-20 Ibc Advanced Technologies, Inc. Compositions and processes for separating and concentrating certain ions from mixed ion solutions using ion-binding ligands bonded to membranes
US5633085A (en) * 1994-06-10 1997-05-27 Potters Industries Inc. Durable composite particle and method of making same
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
JP2862509B2 (ja) * 1996-05-28 1999-03-03 東洋電化工業株式会社 リパーゼ固定化用担体及び固定化リパーゼ
US5935429A (en) * 1997-01-03 1999-08-10 Bio-Rad Laboratories, Inc. Chromatography columns with continuous beds formed in situ from aqueous solutions
SE9700769D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
US6156431A (en) * 1999-01-04 2000-12-05 United Chemical Technologies, Inc. Extraction material comprising treated silica and method for determination of gamma-hydroxybutyrate
US6689715B1 (en) * 2000-02-09 2004-02-10 Hammen Corporation Tethered polymer ligands
WO2004002618A1 (en) * 2002-06-27 2004-01-08 Akzo Nobel N.V. Adsorbent material and method of preparing an adsorbent material
US6994791B2 (en) * 2002-06-27 2006-02-07 Akzo Nobel N.V. Adsorbent material and method of preparing an adsorbent material
JP4225972B2 (ja) * 2002-07-26 2009-02-18 アプレラ コーポレイション 過剰な希釈剤を有する精製カラムを備える微小流体デバイスおよび方法
US8137548B2 (en) * 2003-10-17 2012-03-20 Zirchrom Separations, Inc. Chelator-modified inorganic oxide particles
JP3922648B2 (ja) 2004-05-24 2007-05-30 株式会社資生堂 アフィニティー粒子及びアフィニティー分離方法
US7402243B2 (en) 2004-09-10 2008-07-22 Dionex Corporation Organosilanes and substrate bonded with same
US7468130B2 (en) * 2005-02-15 2008-12-23 Dionex Corporation Organosilanes and substrates covalently bonded with same and methods for synthesis and use same
FR2889078B1 (fr) * 2005-07-27 2007-11-02 Aventis Pharma Sa Nouvelle methode de chromatographie d'affinite d'antithrombine iii
US20070089604A1 (en) * 2005-10-20 2007-04-26 Wu Chen Novel chromatographic stationary phase
DE102006061327A1 (de) * 2006-12-22 2008-06-26 Basf Construction Polymers Gmbh Pfropf-Copolymer, Verfahren zu dessen Herstellung und seine Verwendung
US8580935B2 (en) * 2007-02-26 2013-11-12 Alltech Associates, Inc. Ultra-fast chromatography
EP2142486B1 (en) * 2007-04-16 2018-05-30 James Hardie Technology Limited A method of making a low density additive
US7557232B2 (en) * 2007-05-25 2009-07-07 Dionex Corporation Compositions useful as chromatography stationary phases
EP2258470A4 (en) * 2008-03-19 2012-10-31 Shiseido Co Ltd PROCESS FOR PRODUCING AFFINITY PARTICLES, AFFINITY PARTICLES AND CORRESPONDING SEPARATION METHOD
US20110118382A1 (en) * 2008-05-21 2011-05-19 Roland Reichenbach-Klinke Graft copolymers, method for the production thereof, and use thereof
EP2437882A4 (en) 2009-06-01 2016-11-23 Waters Technologies Corp HYBRID MATERIAL FOR CHROMATOGRAPHY SEPARATIONS
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
US9272260B2 (en) * 2009-08-14 2016-03-01 University Of Louisville Research Foundation, Inc. Methods of synthesis and purification by use of a solid support
EP2598441B1 (en) 2010-07-26 2021-01-06 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous core having narrow particle size distribution; process for the preparation thereof; and use thereof for chromatographic separations
WO2013067171A1 (en) 2011-11-01 2013-05-10 Purdue Research Foundation Protein chromatography matrices with hydrophilic copolymer coatings
US9669402B2 (en) * 2012-03-08 2017-06-06 Bio-Rad Laboratories, Inc. Anionic exchange-hydrophobic mixed mode
CN107754776B (zh) 2012-05-15 2021-09-21 沃特世科技公司 色谱材料
PL2812091T3 (pl) 2012-09-17 2021-07-19 W.R. Grace & Co. - Conn. Podłoża chromatograficzne i urządzenia
SG11201404684RA (en) * 2012-09-17 2014-10-30 Grace W R & Co Functionalized particulate support material and methods of making and using the same
US9610576B2 (en) * 2012-09-27 2017-04-04 Agilent Technologies, Inc. Hydrolytically stable ion-exchange stationary phases and uses thereof
CN104718450B (zh) * 2012-10-18 2018-12-14 捷恩智株式会社 抗体精制用阳离子交换色谱法载体及抗体医药的制程中生产的抗体单体与其聚合物的分离法
EP3936226A3 (en) 2013-06-11 2022-03-16 Waters Technologies Corporation Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
US9518960B2 (en) * 2013-10-02 2016-12-13 Waters Technologies Corporation System and method for rapid analysis of polycyclic aromatic hydrocarbons
US10308669B2 (en) * 2013-12-19 2019-06-04 3M Innovative Properties Company Laminated articles for microbial removal and low pressure drop filtration, methods of making, and methods of using same
US11229896B2 (en) 2014-01-16 2022-01-25 W.R. Grace & Co.—Conn. Affinity chromatography media and chromatography devices
WO2015133507A1 (ja) * 2014-03-05 2015-09-11 Jsr株式会社 固相担体、リガンド結合固相担体、標的物質の検出又は分離方法、固相担体の製造方法、及びリガンド結合固相担体の製造方法
PL3137209T3 (pl) 2014-05-02 2023-01-02 W.R. Grace & Co. - Conn. Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego
JP2018517559A (ja) 2015-06-05 2018-07-05 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 吸着性バイオプロセス清澄化剤並びにその製造及び使用方法
EP3426390A1 (en) 2016-03-06 2019-01-16 Waters Technologies Corporation Porous materials with controlled porosity; process for the preparation thereof; and use thereof for chromatographic separations
CN109414672B (zh) * 2016-07-14 2021-10-26 阿克苏诺贝尔化学品国际有限公司 可热膨胀热塑性微球及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2078974A5 (xx) * 1970-02-25 1971-11-05 Hoffmann La Roche
US3799799A (en) * 1971-04-01 1974-03-26 Fiberglas Canada Ltd Coating of mica reinforcement for composite materials
US3984349A (en) * 1971-07-26 1976-10-05 Societe Rhone-Progil Modified porous bodies
GB1456974A (en) * 1973-01-10 1976-12-01 Nat Res Dev Ion exchange materials
GB1456865A (en) * 1973-12-14 1976-12-01 Pye Ltd Method of bonding copolymers
US3983299A (en) * 1974-03-04 1976-09-28 Purdue Research Foundation Bonded carbohydrate stationary phases for chromatography
SE7712058L (sv) * 1976-11-12 1978-05-13 Ceskoslovenska Akademie Ved Tredimensionell berare av oorganiskt, porost material och en reaktiv polymer och ett forfarande for framstellning derav
JPS5383680A (en) * 1976-12-29 1978-07-24 Toray Silicone Co Filler for gas separation column
JPS54137398A (en) * 1978-04-18 1979-10-25 Sekisui Chemical Co Ltd Filled material for liquid chromatography

Also Published As

Publication number Publication date
FI68636C (fi) 1985-10-10
FI812002L (fi) 1981-12-28
EP0043159A1 (en) 1982-01-06
IE51337B1 (en) 1986-12-10
FI68636B (fi) 1985-06-28
DK153406B (da) 1988-07-11
AU7231681A (en) 1982-01-07
DE3172131D1 (en) 1985-10-10
JPS6216133B2 (xx) 1987-04-10
GR74357B (xx) 1984-06-27
ES503455A0 (es) 1982-12-16
ATE15378T1 (de) 1985-09-15
EP0043159B1 (en) 1985-09-04
IE811394L (en) 1981-12-27
US4415631A (en) 1983-11-15
CA1170643A (en) 1984-07-10
AU548877B2 (en) 1986-01-09
ES8303463A1 (es) 1983-02-16
DK153406C (da) 1988-11-28
DK282681A (da) 1981-12-28
JPS5738937A (en) 1982-03-03

Similar Documents

Publication Publication Date Title
DE3172131D1 (en) Porous inorganic support material coated with an organic stationary phase, for use in chromatography, and process for its preparation
Petro et al. Polymers immobilized on silica gels as stationary phases for liquid chromatography
EP0386926A3 (en) Silica gel supports suitable for chromatographic separations
SE8804073D0 (sv) Selektivt biomolekylinteragerande maetytor foer biosensoranvaendning
ATE199654T1 (de) Beschichtete media für chromatographie
ATE58304T1 (de) Verfahren zur umhuellung von granulaten.
DE69113872D1 (de) Biologisch aktive Reagenzien aus Carboxylgruppenhaltigen Polymerisaten, analytisches Element und Verfahren zur Verwendung.
ES8405281A1 (es) Procedimiento de preparacion de un soporte en particulas para la fabricacion de adsorbentes para cromatografia de afinidad en columna
EP0496473A3 (en) Method of preparing biologically active reagents from succinimide-containing polymers, analytical element and methods of use
US4582875A (en) Method of activating hydroxyl groups of a polymeric carrier using 2-fluoro-1-methylpyridinium toluene-4-sulfonate
US5211993A (en) Method of making novel separation media
JPS6345558A (ja) 逆相充▲てん▼材料
NoMURA et al. Acylation of aminopropyl-bonded silica gel for liquid chromatography
JPS57197034A (en) Preparation of immobilized nucleic acid
EP0113452A3 (en) Magnetic particles as supports for organic synthesis
US5186838A (en) Chromatographic packing material having functionalized polymeric coating on a substrate
Kurganov et al. Ion-exchange high-performance liquid chromatography of nucleotides and polypeptides on new types of ion-exchange sorbents, based on polystyrene-coated silicas
CS962184A1 (en) Zpusob vyroby vysoce aktivnich biologicky ucinnych sloucenin imobilisovanych na nosici
Ivanov et al. Inorganic supports coated with N‐substituted polyacrylamides: Application to biospecific chromatography of proteins
ATE13192T1 (de) Perlpolymerisat und dessen verwendung zur immobilisierung von enzymen.
Schrum The synthesis and characterization of polyacrylate anion-exchange stationary phases for protein separations in liquid chromatography
SU857860A1 (ru) Способ получени сорбента дл хроматографии
Ivanov et al. Structures of grafted polymer phases and features of protein separation on composite anion-exchangers
Mattlasson et al. Affinity Chromatographic Purification of Proteins Using Immobilized Cells
Ratnayake Studies on the synthesis and behavior of acrylate polymer stationary phases for cation exchange chromatography of proteins