ZA812039B - S-acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics - Google Patents

S-acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics

Info

Publication number
ZA812039B
ZA812039B ZA00812039A ZA812039A ZA812039B ZA 812039 B ZA812039 B ZA 812039B ZA 00812039 A ZA00812039 A ZA 00812039A ZA 812039 A ZA812039 A ZA 812039A ZA 812039 B ZA812039 B ZA 812039B
Authority
ZA
South Africa
Prior art keywords
amino acids
carboxyl group
group containing
acylation products
mercaptoacyl amino
Prior art date
Application number
ZA00812039A
Other languages
English (en)
Inventor
M Ondetti
D Ryono
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ZA812039B publication Critical patent/ZA812039B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA00812039A 1980-04-03 1981-03-26 S-acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics ZA812039B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/136,842 US4482725A (en) 1980-04-03 1980-04-03 S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics

Publications (1)

Publication Number Publication Date
ZA812039B true ZA812039B (en) 1982-04-28

Family

ID=22474610

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00812039A ZA812039B (en) 1980-04-03 1981-03-26 S-acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics

Country Status (12)

Country Link
US (1) US4482725A (ja)
JP (1) JPS56156215A (ja)
AU (1) AU546352B2 (ja)
BE (1) BE888247A (ja)
CA (1) CA1197853A (ja)
CH (1) CH653017A5 (ja)
DE (1) DE3113610A1 (ja)
FR (1) FR2479827B1 (ja)
GB (1) GB2073187B (ja)
IT (1) IT1137521B (ja)
NL (1) NL8101641A (ja)
ZA (1) ZA812039B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431644A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
US4431645A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
US4661515A (en) * 1982-07-21 1987-04-28 Usv Pharmaceutical Corporation Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity
US4468396A (en) * 1982-12-20 1984-08-28 Schering Corporation Antihypertensive benzothiadiazines
US4576941A (en) * 1984-02-29 1986-03-18 Usv Pharmaceutical Corp. Compounds for treating hypertension
US4696939A (en) * 1984-02-29 1987-09-29 Usv Pharmaceutical Corporation Benzothiadiazole compounds for treating hypertension
DE3532036A1 (de) * 1985-09-09 1987-03-26 Hoechst Ag Pharmazeutische zubereitung zur behandlung des bluthochdrucks

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058882A (en) * 1959-12-28 1962-10-16 Hoechst Ag N'-substituted-3-carboxy-6-halo-sulfanilamide and derivatives thereof
US3255241A (en) * 1961-01-19 1966-06-07 Merck & Co Inc (2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension
US4140797A (en) * 1976-05-10 1979-02-20 E. R. Squibb & Sons, Inc. Method for alleviating angiotensin related hypertension
ZA777062B (en) * 1976-12-03 1979-02-28 Squibb & Sons Inc Derivatives of thiazolidinecarboxylic acids and related acids
FR2412537A1 (fr) * 1977-12-22 1979-07-20 Science Union & Cie Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique
CA1120400A (en) * 1977-12-27 1982-03-23 Zola P. Horovitz Method of treating hypertension and medicaments therefor
JPS584711B2 (ja) * 1978-08-02 1983-01-27 参天製薬株式会社 ピロリジン誘導体
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives

Also Published As

Publication number Publication date
FR2479827B1 (ja) 1983-03-18
IT8120888A0 (it) 1981-04-02
NL8101641A (nl) 1981-11-02
AU546352B2 (en) 1985-08-29
CH653017A5 (fr) 1985-12-13
GB2073187A (en) 1981-10-14
CA1197853A (en) 1985-12-10
AU6879181A (en) 1981-10-08
FR2479827A1 (ja) 1981-10-09
DE3113610A1 (de) 1982-04-22
IT1137521B (it) 1986-09-10
GB2073187B (en) 1983-09-07
JPH0125751B2 (ja) 1989-05-19
JPS56156215A (en) 1981-12-02
US4482725A (en) 1984-11-13
BE888247A (fr) 1981-10-02

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