IT1137521B - Prodotti di s-acilazione di mercaptoacil ammino acidi e diuoretici contenenti gruppo carbossile - Google Patents

Prodotti di s-acilazione di mercaptoacil ammino acidi e diuoretici contenenti gruppo carbossile

Info

Publication number
IT1137521B
IT1137521B IT8120888A IT2088881A IT1137521B IT 1137521 B IT1137521 B IT 1137521B IT 8120888 A IT8120888 A IT 8120888A IT 2088881 A IT2088881 A IT 2088881A IT 1137521 B IT1137521 B IT 1137521B
Authority
IT
Italy
Prior art keywords
mercaptoacil
diuoretics
acilation
amino acids
carboxy group
Prior art date
Application number
IT8120888A
Other languages
English (en)
Other versions
IT8120888A0 (it
Inventor
Miguel A Ondetti
Denis E Ryono
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8120888A0 publication Critical patent/IT8120888A0/it
Application granted granted Critical
Publication of IT1137521B publication Critical patent/IT1137521B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT8120888A 1980-04-03 1981-04-02 Prodotti di s-acilazione di mercaptoacil ammino acidi e diuoretici contenenti gruppo carbossile IT1137521B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/136,842 US4482725A (en) 1980-04-03 1980-04-03 S-Acylation products of mercaptoacyl amino acids and carboxyl group containing diuretics

Publications (2)

Publication Number Publication Date
IT8120888A0 IT8120888A0 (it) 1981-04-02
IT1137521B true IT1137521B (it) 1986-09-10

Family

ID=22474610

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8120888A IT1137521B (it) 1980-04-03 1981-04-02 Prodotti di s-acilazione di mercaptoacil ammino acidi e diuoretici contenenti gruppo carbossile

Country Status (12)

Country Link
US (1) US4482725A (it)
JP (1) JPS56156215A (it)
AU (1) AU546352B2 (it)
BE (1) BE888247A (it)
CA (1) CA1197853A (it)
CH (1) CH653017A5 (it)
DE (1) DE3113610A1 (it)
FR (1) FR2479827B1 (it)
GB (1) GB2073187B (it)
IT (1) IT1137521B (it)
NL (1) NL8101641A (it)
ZA (1) ZA812039B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431644A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
US4431645A (en) * 1982-03-08 1984-02-14 Schering Corporation Antihypertensive agents
US4661515A (en) * 1982-07-21 1987-04-28 Usv Pharmaceutical Corporation Compounds having angiotensin converting enzyme inhibitory activity and diuretic activity
US4468396A (en) * 1982-12-20 1984-08-28 Schering Corporation Antihypertensive benzothiadiazines
US4696939A (en) * 1984-02-29 1987-09-29 Usv Pharmaceutical Corporation Benzothiadiazole compounds for treating hypertension
US4576941A (en) * 1984-02-29 1986-03-18 Usv Pharmaceutical Corp. Compounds for treating hypertension
DE3532036A1 (de) * 1985-09-09 1987-03-26 Hoechst Ag Pharmazeutische zubereitung zur behandlung des bluthochdrucks

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058882A (en) * 1959-12-28 1962-10-16 Hoechst Ag N'-substituted-3-carboxy-6-halo-sulfanilamide and derivatives thereof
US3255241A (en) * 1961-01-19 1966-06-07 Merck & Co Inc (2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4046889A (en) * 1976-02-13 1977-09-06 E. R. Squibb & Sons, Inc. Azetidine-2-carboxylic acid derivatives
US4140797A (en) * 1976-05-10 1979-02-20 E. R. Squibb & Sons, Inc. Method for alleviating angiotensin related hypertension
US4053651A (en) * 1976-05-10 1977-10-11 E. R. Squibb & Sons, Inc. Compounds and method for alleviating angiotensin related hypertension
ZA777062B (en) * 1976-12-03 1979-02-28 Squibb & Sons Inc Derivatives of thiazolidinecarboxylic acids and related acids
FR2412537A1 (fr) * 1977-12-22 1979-07-20 Science Union & Cie Nouveaux thiobutyramides substitues, leurs procedes d'obtention et leur application pharmaceutique
CA1120400A (en) * 1977-12-27 1982-03-23 Zola P. Horovitz Method of treating hypertension and medicaments therefor
JPS584711B2 (ja) * 1978-08-02 1983-01-27 参天製薬株式会社 ピロリジン誘導体
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives

Also Published As

Publication number Publication date
JPS56156215A (en) 1981-12-02
FR2479827B1 (it) 1983-03-18
US4482725A (en) 1984-11-13
GB2073187B (en) 1983-09-07
NL8101641A (nl) 1981-11-02
DE3113610A1 (de) 1982-04-22
FR2479827A1 (it) 1981-10-09
AU546352B2 (en) 1985-08-29
AU6879181A (en) 1981-10-08
CA1197853A (en) 1985-12-10
CH653017A5 (fr) 1985-12-13
BE888247A (fr) 1981-10-02
IT8120888A0 (it) 1981-04-02
GB2073187A (en) 1981-10-14
ZA812039B (en) 1982-04-28
JPH0125751B2 (it) 1989-05-19

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