ZA806501B - 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents - Google Patents

4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents

Info

Publication number
ZA806501B
ZA806501B ZA00806501A ZA806501A ZA806501B ZA 806501 B ZA806501 B ZA 806501B ZA 00806501 A ZA00806501 A ZA 00806501A ZA 806501 A ZA806501 A ZA 806501A ZA 806501 B ZA806501 B ZA 806501B
Authority
ZA
South Africa
Prior art keywords
aroyl
piperidino
alkyl
antipsychotic agents
butyrophenone
Prior art date
Application number
ZA00806501A
Other languages
English (en)
Inventor
A Carr
R Farr
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of ZA806501B publication Critical patent/ZA806501B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA00806501A 1979-10-27 1980-10-22 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents ZA806501B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8894279A 1979-10-27 1979-10-27

Publications (1)

Publication Number Publication Date
ZA806501B true ZA806501B (en) 1981-10-28

Family

ID=22214421

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00806501A ZA806501B (en) 1979-10-27 1980-10-22 4-(4-alkyl-aroyl-1-piperidino)butyrophenone antipsychotic agents

Country Status (12)

Country Link
JP (1) JPS5673061A (fr)
AU (1) AU6369480A (fr)
BE (1) BE885894A (fr)
CA (1) CA1148162A (fr)
DE (1) DE3039974A1 (fr)
ES (1) ES8201550A1 (fr)
FR (1) FR2468592A1 (fr)
GB (1) GB2061937A (fr)
IL (1) IL61340A0 (fr)
IT (1) IT1146198B (fr)
NL (1) NL8005890A (fr)
ZA (1) ZA806501B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ577114A (en) * 2006-12-19 2011-12-22 Hoffmann La Roche Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE713746C (de) * 1939-03-31 1941-11-18 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von 4-Arylpiperidyl-4-ketonen
US3080372A (en) * 1960-03-25 1963-03-05 Res Lab Dr C Janssen 1-aroylalkyl-4-arylpiperidine derivatives
CH492708A (de) * 1968-01-11 1970-06-30 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
CH498836A (de) * 1968-12-20 1970-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3852455A (en) * 1970-11-27 1974-12-03 Richardson Merrell Inc 4-{8 4({60 hydroxybenzyl)piperidino{9 -4-fluorobutyrophenone derivatives as tranquilizers
ZA717147B (en) * 1970-11-27 1972-07-26 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives
US3888867A (en) * 1972-05-03 1975-06-10 Richardson Merrell Inc 4-(4-(alpha-hydroxybenzyl)piperidino)4'-fluorobutyrophenone derivatives
US4101662A (en) * 1973-05-03 1978-07-18 A. H. Robins Company, Incorporated Method for inhibiting emesis and compositions therefor
SE7409245L (fr) * 1973-07-19 1975-01-20 Robins Co Inc A H
GB1535791A (en) * 1975-05-07 1978-12-13 Ferrosan Ab Derivatives of 4-piperidinol
CH602642A5 (fr) * 1975-11-14 1978-07-31 Orgamol Sa
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use

Also Published As

Publication number Publication date
BE885894A (fr) 1981-02-16
IL61340A0 (en) 1980-12-31
FR2468592A1 (fr) 1981-05-08
ES496204A0 (es) 1981-12-01
JPS5673061A (en) 1981-06-17
DE3039974A1 (de) 1981-05-07
ES8201550A1 (es) 1981-12-01
FR2468592B1 (fr) 1983-08-05
AU6369480A (en) 1981-04-30
NL8005890A (nl) 1981-04-29
IT1146198B (it) 1986-11-12
CA1148162A (fr) 1983-06-14
GB2061937A (en) 1981-05-20
IT8049998A0 (it) 1980-10-24

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