ZA80441B - New analogs of prostacyclin,intermediate products thereof,processes for their preparation and their use as medicaments - Google Patents

New analogs of prostacyclin,intermediate products thereof,processes for their preparation and their use as medicaments

Info

Publication number
ZA80441B
ZA80441B ZA00800441A ZA80441A ZA80441B ZA 80441 B ZA80441 B ZA 80441B ZA 00800441 A ZA00800441 A ZA 00800441A ZA 80441 A ZA80441 A ZA 80441A ZA 80441 B ZA80441 B ZA 80441B
Authority
ZA
South Africa
Prior art keywords
preparation
prostacyclin
medicaments
intermediate products
processes
Prior art date
Application number
ZA00800441A
Other languages
English (en)
Inventor
B Schoelkens
E Konz
W Bartmann
U Lerch
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA80441B publication Critical patent/ZA80441B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
  • Paints Or Removers (AREA)
ZA00800441A 1979-01-25 1980-01-24 New analogs of prostacyclin,intermediate products thereof,processes for their preparation and their use as medicaments ZA80441B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792902809 DE2902809A1 (de) 1979-01-25 1979-01-25 Neue analoga von prostacyclin

Publications (1)

Publication Number Publication Date
ZA80441B true ZA80441B (en) 1981-01-28

Family

ID=6061363

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00800441A ZA80441B (en) 1979-01-25 1980-01-24 New analogs of prostacyclin,intermediate products thereof,processes for their preparation and their use as medicaments

Country Status (11)

Country Link
US (1) US4312882A (fr)
EP (1) EP0013955B1 (fr)
JP (1) JPS55100376A (fr)
AT (1) ATE3640T1 (fr)
AU (1) AU539763B2 (fr)
CA (1) CA1207761A (fr)
DE (2) DE2902809A1 (fr)
ES (1) ES487818A0 (fr)
HU (1) HU184767B (fr)
IL (1) IL59209A (fr)
ZA (1) ZA80441B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3029984C2 (de) * 1980-08-08 1983-12-15 Grünenthal GmbH, 5190 Stolberg 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel
DE3107100A1 (de) * 1981-02-20 1982-09-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Azaprostacycline, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
DE3147714A1 (de) * 1981-11-27 1983-06-01 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue prostacycline und verfahren zu ihrer herstellung
JPS6130554A (ja) * 1984-07-23 1986-02-12 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤
US5221689A (en) * 1984-07-23 1993-06-22 Ono Pharmaceutical Co., Ltd. Prostaglandin analogues, processes for their preparation and pharmaceutical compositions containing them
CN107129495B (zh) * 2017-05-18 2019-04-19 厦门大学 一种毒扁豆碱前体化合物的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2351112A1 (fr) * 1975-10-21 1977-12-09 Wellcome Found Derive de prostaglandine et medicament contenant ce derive
US4158667A (en) * 1976-02-04 1979-06-19 The Upjohn Company 6-Keto PGF analogs
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
JPS53116365A (en) * 1977-03-22 1978-10-11 Ono Pharmaceut Co Ltd Prostaglandin x analogous compounds and process for their preparation
JPS53103464A (en) * 1977-02-21 1978-09-08 Ono Pharmaceut Co Ltd Prostaglandin x analogues and process for their preparation
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
JPS53136513A (en) 1977-05-06 1978-11-29 Ono Pharmaceut Co Ltd Stabilization of prostaglandin-x-related compounds
DE2753244A1 (de) * 1977-11-25 1979-06-07 Schering Ag Neue prostacyclinderivate und verfahren zu ihrer herstellung
IT1088036B (it) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
JPS54115368A (en) * 1978-03-01 1979-09-07 Ono Pharmaceut Co Ltd Prostaglandin i2 analog, its preparation, and drug composition containing it as active constituent
JPS54115367A (en) * 1978-03-01 1979-09-07 Ono Pharmaceut Co Ltd Prostaglandin i2 analog, its preparation, and drug composition containing it as active constituent

Also Published As

Publication number Publication date
AU5490280A (en) 1980-07-31
IL59209A (en) 1987-10-30
AU539763B2 (en) 1984-10-18
CA1207761A (fr) 1986-07-15
DE2902809A1 (de) 1980-08-07
EP0013955A1 (fr) 1980-08-06
US4312882A (en) 1982-01-26
HU184767B (en) 1984-10-29
IL59209A0 (en) 1980-05-30
JPS55100376A (en) 1980-07-31
DE3063556D1 (en) 1983-07-07
ES8102563A1 (es) 1981-01-16
ATE3640T1 (de) 1983-06-15
ES487818A0 (es) 1981-01-16
EP0013955B1 (fr) 1983-06-01

Similar Documents

Publication Publication Date Title
IE822648L (en) 7-oxabicycloheptane and 7-oxabicycloheptene compounds.
ES8502987A1 (es) Procedimiento para preparar nuevos benzo (b) tiofenos
DE2966406D1 (en) Esters of stilbene derivatives, process for their preparation, stilbene-alcohols as intermediate products, use of the esters as insecticides
ZA80441B (en) New analogs of prostacyclin,intermediate products thereof,processes for their preparation and their use as medicaments
IL52227A (en) Process for the preparation of 10,19-dihydro-vitamin d derivatives and some novel 10,19-dihydro-1alpha-hydroxy and 1 alpha,25-dihydroxy-vitamin d3 compounds and pharmaceutical compositions containing them
DE3064109D1 (en) Pseudotrisaccharides, their preparation and use as medicaments
ES478530A1 (es) Procedimiento para la preparacion de nuevos compuestos ana- logos de prostaciclina.
JPS51111896A (en) Hollow articles for medical equipment
CA1268468C (fr) Analogues des prostaglandines avec groupement thiabicycloheptane substitue
IL59768A (en) Prostaglandin derivatives of the 6-keto-pge1 series,process for their preparation and pharmaceutical compositions containing them
YU225375A (en) Process for obtaining derivatives of 5-endo-(3-indocarbonyloxy)-n-aminoalkyl-(bicyclo)(2.2.1)heptane-2,3-diendo-carboxylic acid
ATE25517T1 (de) Delta-1-pyrrolin-thiolactimaether und verfahren zu ihrer herstellung.
CH613966A5 (en) Process for the preparation of novel 5-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazoles
IL51140A (en) Process for the preparation of 1-carbamoyl-3-(3,5-dichlorophenyl)-hydantoins
DE3160933D1 (en) Imidazolyl-indene-thiophenes, process for their preparation and their use as medicaments
JPS5265300A (en) Synthesis of 2-thioadenosines
ATE24718T1 (de) Alkylcycloalkyl-imidazolylmethyl-ketone und verfahren zu ihrer herstellung.
JPS51138698A (en) Process preparing 2-cycloalkylthioadenine s
DE3461926D1 (en) Cycloaliphatic aminosulphonic-acid derivatives, process for their production and pharmaceutical preparations for combating heart and vascular diseases
JPS51136643A (en) Process for preparation of aromatic ester derivatives
JPS5219654A (en) Preparation of ng-substituted-n2- substituted-alginamides and acid add ition salts thereof
JPS51141858A (en) Process for preparing novel 1alpha,2alpha-epoxycholest-5-ene-3-one.
JPS51131874A (en) Process for preparation of 7-14- diazadispiro(5.1.5.2)-pentadecane-15- on
JPS5265256A (en) Synthesis of 6,7-exo-trimethylene-bicyclo 3,2,1 -oct-2-ene
JPS5242850A (en) Process for preparation of novel allenediol and its derivatives