ES487818A0 - Procedimiento para la preparacion de nuevas sustancias analogas de prostaciclina - Google Patents
Procedimiento para la preparacion de nuevas sustancias analogas de prostaciclinaInfo
- Publication number
- ES487818A0 ES487818A0 ES487818A ES487818A ES487818A0 ES 487818 A0 ES487818 A0 ES 487818A0 ES 487818 A ES487818 A ES 487818A ES 487818 A ES487818 A ES 487818A ES 487818 A0 ES487818 A0 ES 487818A0
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- prostacicline
- procedure
- new analog
- action
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title 1
- KAQKFAOMNZTLHT-OZUDYXHBSA-N prostaglandin I2 Chemical compound O1\C(=C/CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-OZUDYXHBSA-N 0.000 abstract 2
- 101000862089 Clarkia lewisii Glucose-6-phosphate isomerase, cytosolic 1A Proteins 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000004351 coronary vessel Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960001123 epoprostenol Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 150000003815 prostacyclins Chemical class 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paints Or Removers (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792902809 DE2902809A1 (de) | 1979-01-25 | 1979-01-25 | Neue analoga von prostacyclin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8102563A1 ES8102563A1 (es) | 1981-01-16 |
| ES487818A0 true ES487818A0 (es) | 1981-01-16 |
Family
ID=6061363
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES487818A Granted ES487818A0 (es) | 1979-01-25 | 1980-01-18 | Procedimiento para la preparacion de nuevas sustancias analogas de prostaciclina |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4312882A (es) |
| EP (1) | EP0013955B1 (es) |
| JP (1) | JPS55100376A (es) |
| AT (1) | ATE3640T1 (es) |
| AU (1) | AU539763B2 (es) |
| CA (1) | CA1207761A (es) |
| DE (2) | DE2902809A1 (es) |
| ES (1) | ES487818A0 (es) |
| HU (1) | HU184767B (es) |
| IL (1) | IL59209A (es) |
| ZA (1) | ZA80441B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3029984C2 (de) * | 1980-08-08 | 1983-12-15 | Grünenthal GmbH, 5190 Stolberg | 2-Oxabicyclo [3.3.0] octanderivate und diese enthaltende Arzneimittel |
| DE3107100A1 (de) * | 1981-02-20 | 1982-09-09 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Azaprostacycline, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
| DE3147714A1 (de) * | 1981-11-27 | 1983-06-01 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacycline und verfahren zu ihrer herstellung |
| US5221689A (en) * | 1984-07-23 | 1993-06-22 | Ono Pharmaceutical Co., Ltd. | Prostaglandin analogues, processes for their preparation and pharmaceutical compositions containing them |
| JPS6130554A (ja) * | 1984-07-23 | 1986-02-12 | Ono Pharmaceut Co Ltd | プロスタグランジン類似化合物のある特定の立体配置を有する異性体及びそれらを有効成分として含有する治療剤 |
| CN107129495B (zh) * | 2017-05-18 | 2019-04-19 | 厦门大学 | 一种毒扁豆碱前体化合物的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2351112A1 (fr) * | 1975-10-21 | 1977-12-09 | Wellcome Found | Derive de prostaglandine et medicament contenant ce derive |
| US4158667A (en) * | 1976-02-04 | 1979-06-19 | The Upjohn Company | 6-Keto PGF analogs |
| JPS53103464A (en) * | 1977-02-21 | 1978-09-08 | Ono Pharmaceut Co Ltd | Prostaglandin x analogues and process for their preparation |
| JPS53116365A (en) * | 1977-03-22 | 1978-10-11 | Ono Pharmaceut Co Ltd | Prostaglandin x analogous compounds and process for their preparation |
| US4178367A (en) * | 1977-02-21 | 1979-12-11 | Ono Pharmaceutical Co. Ltd. | Prostaglandin I2 analogues |
| HU182583B (en) * | 1977-03-01 | 1984-02-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing prostacyclin and analogues thereof |
| AU524786B2 (en) * | 1977-03-07 | 1982-10-07 | The Upjohn Company | Prostacyclins |
| JPS53136513A (en) | 1977-05-06 | 1978-11-29 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin-x-related compounds |
| DE2753244A1 (de) * | 1977-11-25 | 1979-06-07 | Schering Ag | Neue prostacyclinderivate und verfahren zu ihrer herstellung |
| IT1088036B (it) * | 1977-11-25 | 1985-06-04 | Erba Carlo Spa | 15-epi-prostaciclina e prostaciclina analoghi |
| JPS54115367A (en) * | 1978-03-01 | 1979-09-07 | Ono Pharmaceut Co Ltd | Prostaglandin i2 analog, its preparation, and drug composition containing it as active constituent |
| JPS54115368A (en) * | 1978-03-01 | 1979-09-07 | Ono Pharmaceut Co Ltd | Prostaglandin i2 analog, its preparation, and drug composition containing it as active constituent |
-
1979
- 1979-01-25 DE DE19792902809 patent/DE2902809A1/de not_active Withdrawn
-
1980
- 1980-01-18 ES ES487818A patent/ES487818A0/es active Granted
- 1980-01-21 EP EP80100262A patent/EP0013955B1/de not_active Expired
- 1980-01-21 AT AT80100262T patent/ATE3640T1/de not_active IP Right Cessation
- 1980-01-21 DE DE8080100262T patent/DE3063556D1/de not_active Expired
- 1980-01-23 IL IL59209A patent/IL59209A/xx unknown
- 1980-01-23 US US06/114,684 patent/US4312882A/en not_active Expired - Lifetime
- 1980-01-24 CA CA000344316A patent/CA1207761A/en not_active Expired
- 1980-01-24 ZA ZA00800441A patent/ZA80441B/xx unknown
- 1980-01-24 AU AU54902/80A patent/AU539763B2/en not_active Ceased
- 1980-01-24 HU HU80146A patent/HU184767B/hu unknown
- 1980-01-25 JP JP769280A patent/JPS55100376A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU539763B2 (en) | 1984-10-18 |
| JPS55100376A (en) | 1980-07-31 |
| HU184767B (en) | 1984-10-29 |
| AU5490280A (en) | 1980-07-31 |
| CA1207761A (en) | 1986-07-15 |
| DE3063556D1 (en) | 1983-07-07 |
| DE2902809A1 (de) | 1980-08-07 |
| IL59209A0 (en) | 1980-05-30 |
| ES8102563A1 (es) | 1981-01-16 |
| EP0013955B1 (de) | 1983-06-01 |
| IL59209A (en) | 1987-10-30 |
| ATE3640T1 (de) | 1983-06-15 |
| US4312882A (en) | 1982-01-26 |
| EP0013955A1 (de) | 1980-08-06 |
| ZA80441B (en) | 1981-01-28 |
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